Rheumatology Flashcards

0
Q

Saddle nose deformity

A

Wegeners
Relapsing polychondritis
Syphilis

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1
Q

Diseases associated with anterior uveitis

A
Spondyloarthritis
Sarcoidosis
Behcet disease
JIA
Wegener's
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2
Q

Anti-CCP antibodies

A

Rheumatoid arthritis

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3
Q

Anti-Ro antibodies

A

Sjogren’s, Neonatal heart block

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4
Q

Anti-La antibodies

A

Sjogren’s, Neonatal SLE

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5
Q

p-ANCA

A

Churg-Strauss, microscopic polyangiitis

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6
Q

Anti-myeloperoxidase antibodies

A

Churg-Strauss, microscopic polyangiitis

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7
Q

Anti-proteinase-3 antibodies

A

Granulomatosis with polyangiitis (Wegener’s)

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8
Q

c-ANCA

A

Granulomatosis with polyangiitis (Wegener’s)

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9
Q

Anti-smooth muscle antibody

A

Autoimmune hepatitis

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10
Q

Anti-centromere pattern of ANA

A

CREST/Limited cutaneous systemic sclerosis

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11
Q

Anti-dsDNA

A

SLE

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13
Q

Anti-Jo 1 antibody

A

Polymyositis

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14
Q

Anti-RNP antibody

A

Mixed connective tissue disease

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15
Q

Anti-scl-70 antibody (Anti-topoisomerase)

A

Scleroderma/Diffuse cutaneous systemic sclerosis

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16
Q

Treatment for dermatomyositis

A

High-dose steroids

IF REFRACTORY: methotrexate, azathioprine, IVIg
For cutaneous manifestations: hydroxychloroquine

17
Q

Treatment of fibromyalgia

A

Pregabalin, SNRIs (duloxetine)

18
Q

Anti-cardiolipin antibody

A

Anti-phospholipid syndrome

19
Q

β2 glycoprotein I antibody assay

A

Anti-phospholipid syndrome

20
Q

dilute Russell viper venom time

A

Anti-phospholipid syndrome

21
Q

Flowing osteophytes along the anterolateral aspect of at least four contiguous vertebral bodies

A

Diffuse idiopathic skeletal hyperostosis

22
Q

Two types of cryoglobulinemia

A

Type 1: Monoclonal with paraproteins (e.g. Sjogren’s)

Type 2: Mixed/monoclonal - usually with active Hep C infection

23
Q

Causes of erythema nodosum

A
  • Pregnancy
  • Sarcoidosis
  • IBD
  • Collagen vascular disorders (dermatomyositis, SLE, scleroderma)
  • Malignancy
  • Sweet syndrome
  • Behcet disease
24
Q

TNF-alpha inhibitors

A

Etanercept, infliximab, adalimumab

Associated with drug-induced lupus

25
Q

Drug requiring annual ophtho follow-up; may cause corneal disorder/retinopathy

A

Hydroxychloroquine

26
Q

Anti-Smith antibodies

A

SLE (most specific)