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PT Across the LIFESPAN > Rheumatoid Disease > Flashcards

Rheumatoid Disease Flashcards

1
Q

Systemic auto-immune disease characterized by symmetrical inflammation the synovial Membrane in 5 or more joints.

A

Rheumatoid Arthritis

Most common of the inflammatory diseases

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2
Q

True or false, RA can affect blood vessels, heart, lungs etc

A

true

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3
Q

this type of RA consists on one episode which ends within 2-5 year of initial diagnosis. May be the result from early dx or aggressive treatment.

A

Monocyclic RA

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4
Q

this type of RA continues to increase in severity and is unremitting

A

Progressive RA

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5
Q

in this type of RA, The levels of disease activity fluctuate over the course of the condition.

A

Polyciclic RA

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6
Q

One natural history study found that 75% of people with RA experienced remission within ____years of diagnosis.

A

five

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7
Q

Peak age onset of RA is _____ of age

A

60 years

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8
Q

Primary pathological event in this disease takes place in the synovium, suggesting the offending agent is carried to the joint via the bloodstream

A

RA

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9
Q

an invasive granulation tissue that invades. and erodes subchondral bone and cartilage

A

pannus

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10
Q

In RA, Synovium hypertrophies and will produce
_________:

an invasive granulation tissue that invades
and erodes subchondral bone and cartilage

A

pannus

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11
Q

THE 2010 American College of Rheumatology CLASSIFICATION CRITERIA FOR RHEUMATOID ARTHRITIS

A

a score of ≥6/10 is needed for classification of a
patient as having definite RA

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12
Q

RA, differential diagnosis

A
  • systemic lupus erythematosus
  • psoriatic arthritis
  • gout
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13
Q

RA co-morbidities:

A
  • Cardiovascular disease: ischemic heart disease.
  • Infections
    • Tuberculosis, due to inmmunosuppresion.
  • Mental health conditions
    • Anxiety and depression due to decrease physical function.
  • Malignancies
    • increase incidence of lymphoproliferative malignancies (such as leukemia and
      multiple myeloma).
  • Systemic complications
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14
Q

Systemic Complications in RA:

A
  • Vasculitis: Inflammation of blood vessels
  • Peripheral neuropathies
  • Spinal cord compression
  • Pleuritis
  • Pulmonary nodules
  • Scleritis: Can lead to blindness
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15
Q

Acute RA:

A

Pain, swelling, redness about joints

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16
Q

RA clinical features:

A
  • Pain swelling, redness in joints.
  • Genrealized malaise (low fever)
  • Limited ROM
  • Deformities
  • Morning stiffness of at least 1 hour
  • Symmetric
  • (+) rheumatoid factor
  • radiographic changes
  • subcutaneous rheumatoid nodules.
17
Q

true or false, osteoporosis may be seen in RA

A

true

18
Q
  • Chronic synovial inflammation of unknown cause
  • before age 16
  • Symptoms last from 6 weeks to 3 months
  • One or more joints
  • Often accompanied by fever, rash, eye inflammation (uveitis)
A

Juvenile Rheumatoid Arthritis

Juvenile Idiopathic Arthritis

19
Q

RA, CHANGES IN CERVICAL SPINE

A
  • Affects cervical spine in over 50% patients within first 10 years.
  • Common findings: narrow facet joints
    and intervertebral joints
  • Subluxation of Atlanto-axial joint from laxity of transverse ligament
20
Q

______________________act by altering the underlying disease (RA) rather than treating symptoms. They’re not painkillers, but they’ll reduce pain, swelling and stiffness over a period of weeks or months by slowing down the disease and its effects on the joints.

A

Disease-modifying anti-rheumatic drugs (DMARDs)

There are two types: conventional DMARDs and biological therapies.

21
Q

side effects of corticosteroids tx fro RA include:

A

thinning of bones, weight gain

22
Q

Balancing a to reflect fatigue and energy levels is one of the most important coping mechanisms for people with ____and fatigue, according to a report in the May 2013 issue of the journal Clinical Rheumatology.

A

RA

23
Q

__________may ease pain and inflammation in people with rheumatoid arthritis. Some
suggest ___________capsules may be as effective for relieving pain and inflammation as nonsteroidal anti-inflammatory drugs

A

Fish oil

24
Q

American Rheumatism Association lists 4
criteria for diagnosis of JRA:

A
  1. Chronic synovial inflammation of unknown cause
  2. Onset in children younger than 16 y.o.a.
  3. Evidence of arthritis in 1 or more joints for 6 consecutive weeks
  4. Exclusion of other diseases
    • Lyme disease, Lupus, bone disorders, cancer
25
Q

categories of JRA:

A
  • PAUCIARTICULAR / OLIGOARTICULAR: 4 or fewer joints within first 6 months of symptoms
  • POLYARTICULAR: 5 or more joints
  • SYSTEMIC: illness begins with high spiking
    fevers likely complicated by pericarditis, pleural effusions, enlargement of liver, spleen, lymph nodes
  • PSORIATIC ARTHRITIS: Arthritis with
    psoriasis
26
Q

polyarticular JRA:

A

5 or more joints

27
Q

PAUCIARTICULAR / OLIGOARTICULAR juvenile RA:

A

4 or fewer joints within first 6 months of symptoms

28
Q

Oligoarticular juvenile idiopathic arthritis (formerly called pauciarthritis or pauciarticular-onset juvenile rheumatoid arthritis) is defined as juvenile idiopathic arthritis (JIA) involving fewer than_____joints

A

five

29
Q

Chronic progressive inflammatory arthritis characterized by joint sclerosis & ligamentous ossification moslty occuring in SI jts & spinal facet jts

A

ANKLYOSING SPONDYLITIS

30
Q

cause of anklyosing spondylitis

A

genetic factors

31
Q

onset of anklyosing spondylitis

A

Insidious onset: late adolescence/early adulthood

32
Q

patients describe insidious onset of LBP with stiffness in the morning. LBP/bilat SI jt pain; may have pain in
buttocks/hips – Pain relieved with activity, worsens
with rest/inactivity

A

ANKYLOSING SPONDYLITIS

33
Q
A

classic bamboo spine radiographic appearance of ANKLYOSING SPONDYLITIS

PT Across the LIFESPAN (13 decks)

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