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Rheumatology Harrison's > Rheumatoid Arthritis > Flashcards

Rheumatoid Arthritis Flashcards

1
Q

TRUE or FALSE: Symmetric arthritis

A

True

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2
Q

Biomarkers of prognostic signifance

A

RF, anti-CCPs

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3
Q

Morning joint stiffness for how long

A

1 hr or more

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4
Q

Most frequently affected joints

A

MCP, wrists, PIP

*Osteoarthritis: DIP

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5
Q

Frequent hallmark of RA

A

Flexor tendon tenosynovitis

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6
Q

Hyperextendion of PIP, flexion of DIP

A

Swan-neck deformity

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7
Q

Flexion of the PIP and hyperextension of the DIP

A

Buotonnière deformity

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8
Q

Subluxation of the First MCP joint + hyperextension of the first IP joint

A

Z-line deformity

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9
Q

Inflamed ulnar styloid + tenosynovitis of the extensor carpi ulnaris (sublixation of distal ulna) results in

A

Piano key movement

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10
Q

Spine involvment

A

Atlantoaxial involvement of the cervical spine

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11
Q

Spine rarely affected by RA

A

Thoracic and lumbar

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12
Q

Felty’s syndrome

A

Nodular RA
Splenomegaly
Neutropenia

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13
Q

Allele with greatest risk of RA

A

HLA DRB1

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14
Q

Pulmonary nodulosis

Pneumoconiosis following silica exposure

A

Caplan’s syndrome

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15
Q

Lung involvement

A

Interstitial lung disease

Restrictive

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16
Q

Type of leukemia that develops early in RA

A

T cell large granular lymphocytic leukemia

17
Q

Most common pulmo manifestation in RA

A

Pleuritis

18
Q

Type of pleural effusion in RA

A

Exudative with neutrophils and monocytes

19
Q

Most common valvular abnomality in RA

A

Mitral valve

20
Q

Painful, asymmetrical, asynchronous sensory and motor peripheral neuropathy involving isolated damage to at least 2 separate nerve areas

A

Mononeuritis multiplex

21
Q

Most common hema abnormality

A

Normo normo anemia

22
Q

Most common histopathologic type of lymphoma in RA

A

Diffuse large B cell lymphoma

23
Q

The most common cause of death in RA

A

Cardiovascular disease

24
Q

Thickened cellular membrane containing fibroblast-like synoviocytes and granulation-reactive fibrovascular tissue that invades the underlying cartilage and bone

A

Pannus

25
Q

Incidence dexreases after age

A

75

26
Q

Incidence increased risk in between ages

A

22-55

27
Q

How many percent are positive of RF in those with RA

A

70-80%

28
Q

EULAR CRITERIA SCORE OF RA

A

> /= 6

29
Q

Shoretining in life expectancy

A

Men 7 years

Women 3 years

Rheumatology Harrison's (12 decks)

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