Rheumatoid Arthritis Flashcards
TRUE or FALSE: Symmetric arthritis
True
Biomarkers of prognostic signifance
RF, anti-CCPs
Morning joint stiffness for how long
1 hr or more
Most frequently affected joints
MCP, wrists, PIP
*Osteoarthritis: DIP
Frequent hallmark of RA
Flexor tendon tenosynovitis
Hyperextendion of PIP, flexion of DIP
Swan-neck deformity
Flexion of the PIP and hyperextension of the DIP
Buotonnière deformity
Subluxation of the First MCP joint + hyperextension of the first IP joint
Z-line deformity
Inflamed ulnar styloid + tenosynovitis of the extensor carpi ulnaris (sublixation of distal ulna) results in
Piano key movement
Spine involvment
Atlantoaxial involvement of the cervical spine
Spine rarely affected by RA
Thoracic and lumbar
Felty’s syndrome
Nodular RA
Splenomegaly
Neutropenia
Allele with greatest risk of RA
HLA DRB1
Pulmonary nodulosis
Pneumoconiosis following silica exposure
Caplan’s syndrome
Lung involvement
Interstitial lung disease
Restrictive
Type of leukemia that develops early in RA
T cell large granular lymphocytic leukemia
Most common pulmo manifestation in RA
Pleuritis
Type of pleural effusion in RA
Exudative with neutrophils and monocytes
Most common valvular abnomality in RA
Mitral valve
Painful, asymmetrical, asynchronous sensory and motor peripheral neuropathy involving isolated damage to at least 2 separate nerve areas
Mononeuritis multiplex
Most common hema abnormality
Normo normo anemia
Most common histopathologic type of lymphoma in RA
Diffuse large B cell lymphoma
The most common cause of death in RA
Cardiovascular disease
Thickened cellular membrane containing fibroblast-like synoviocytes and granulation-reactive fibrovascular tissue that invades the underlying cartilage and bone
Pannus
Incidence dexreases after age
75
Incidence increased risk in between ages
22-55
How many percent are positive of RF in those with RA
70-80%
EULAR CRITERIA SCORE OF RA
> /= 6
Shoretining in life expectancy
Men 7 years
Women 3 years
