Gout

Question 1

Heberden’s nodes

Answer 1

Heberden’s nodes are hard or bony swellings that can develop in the distal interphalangeal joints (DIP)

Question 2

Bouchard Nodes

Answer 2

These nodes are actually bony enlargements of the middle joints of the fingers, also known as the PIP joints or proximal interphalangeal joints.

Question 3

Aoncider purine overproduction at this level of uric acid urinary excretion

Answer 3

Greater than 800mg per 24H

Question 4

Most commonly involed joint

Answer 4

1st MTP

Question 5

Goal if with Tophi

Answer 5

UA less than 5

Question 6

Dosing of colchicine

Answer 6

0.6mg -1.2mg tablets Q6-8 for acute attack

Question 7

Duration of colchine

Answer 7

For 6 months with no attacks or as long as tophi are present

Question 8

Crystal in Gout

Answer 8

Monosodium urate

Question 9

Conditions associated with Calcium Pyrophosphate Dihydrate) crystal deposition disease

pseudogout

Answer 9

Hyperparathyroid
Hemochromatosis
Hypophoapatasia
Hypomagnesemia

Question 10

Most frequently involved joint in CPPD

Answer 10

Knee

Question 11

High likelihood of CPPD in radiographs

Answer 11

Punctwte and or linear radiodense deposits

Chondrocalcinosis

Question 12

CPPD on polarized might microscopy

Answer 12

Rhomboid, square, rod-like crystals with weak positive birefromgence

Question 13

Synovial fluid leukocyte counts in CADD

Answer 13

<2000

Question 14

Calcium oxalate deposition disease

Causes

Answer 14

Primary oxalosis: inc production and deposition: nephrocalcinosis, renal failure, death before 20 years old

Question 15

Avoid this vitamin in dialysis patients because it inc hyperoxalsosis

Answer 15

Ascorbic acid

Question 16

Caox crystals

Answer 16

Vari shaped variable birefringence

Bioyramidal strong birefringence
Stains with alizarin red S