Rheumatoid Arthritis Flashcards
There are two types of rheumatoid diseases (articular and non articular). What is each type composed of?
- Articular composes of inflammatory (rheumatoid arthritis, SPA, and other) and degenerative (hand, large joints and spine)
- Non-articular composes of generalised and local
RA always affects ___ joints +/- ____ joints. It is always sym_______
small
large
symmetrical
Rheumatoid arthritis usually has a ___ onset over ____ to months. SOME (15-20%) have a more ___ onset that develops over ___ to weeks. About (8-15%) have ____ onset of symptoms that develop over days
slow weeks rapid days acute
What are some RA non joint features?
- Nodules
- Sicca (dry eyes/ mouth)
- Eyes
- Others (uncommon)
Causes of RA?
- Genetic (complex) due to HLA gene
- Trigger (infection/virus/ injury)
If RA is left untreated, it can lead to
Disability
Damage
Deformity
Death
Treatment and prognosis of RA
- NSAIDS
- Steroids
- Slow acting disease modifying drugs
- Biologic disease modifying drugs
- SURGERY!
Surgical intervention methods include:
Disadvantages are:
- Removal of inflamed synovium
- arthroplasty
- high risk procedures
- questionable outcomes
Other inflammatory rheumatoid diseases other than RA?
UNCOMMON but SIGNIFICANT IMPACT
- Systemic lupus (SLE)
- Scleroderma
- Myositis
- Vasculitis
SLE is an
autoimmune disease of the body’s connective tissues. It affects the tissues throughout the body
SLE can affect any joints but the most common spots are the:
wrists, knees and hands.
What is the frequency and duration of the pain associated with SLE?
Can come and go, or can be long lasting.
In SLE, the ___ tissues surrounding the joints are often ______. But there is NO EXCESS ____.
soft
swollen
fluid
Lupus can also affect the nervous system causing:
headaches
seizures
organic brain syndrome
What is the most common degenerative articular rheumatic disease
Osteoarthritis
What is osteoarthritis characterised by?
progressive loss of cartilage and reaction changes at the margins of the join and in the subchrondal bone
Osteoporosis:
- In early disease, pain occurs only after ____ use and is relieved by ____
- As the disease progresses, pain occurs with minimal _____ or even at ____
- _______ pain is commonly associated with severe disease
joint rest motion rest nocturnal
Treatments and prognosis of degenerative joint disease:
What is the problem with this for osteoarthritis?
- Meds
- Early PT/ exercises
- Heat/ cold therapy
- Joint protection
- Surgery
Osteoarthritis is a slowly progressive disease. The eventual outcome is complete destruction of the joint, and ultimately surgical intervention is required.
Name a generalised non articular rheumatoid disorder.
Fibromyalgia syndrome
Name a local non articular rheumatoid disorder.
Tendonitis
Soft tissue rheumatism
