Rheumatoid Arthritis Flashcards
Causes of RA
genetic, hormonal, environmental and lifestyle factors
what is synovitis
inflammation of the synovial joints
What is pannus
protein released from vascular cells and can lead to thickening of the synnovial membrane. can lead to pain and swelling
cachexia
Wasting, low appetitie, they may lose muscle bulk and atrophy. goes along with advanced alcoholism.
joint instability
if synovial fluid and synovial lining are not strong, we will get shifting and malalignment
joint deformity
structures are weakened and distrupted. a lot in the hands and in the wrists.
Symptons
symmetric, polyarticular pain and swelling during inflammatory stage
morning stiffness
malaise
fatigue
upper and lower limb involvement
common stages of RA
acute -
subacute -
chronic active -
chronic inactive -
look these up in the book.
Hand deformities can have what characteristics
persistent synovitis
disrupted joint structures
altered joint mechanics
normal and abnormal forces over joints
ulnar side of wrist is early site of inflammation - radial wrist deviation compression.
Medical management of RA
no cure, early intervention can slow progression, pharmacotherapy, early drug therapies manage synovial tissues, reduce subsequent deformities, surgery, multidisciplinary team
osteoarthritis is a
clinical syndrome of joint pin linked to degenerative joint changes
most commonly affect hip, knee and shoulder
most common form of arthritis
leading cause of disablity worldwide
most prevalent in women over 50 and men less than 45
characteristcs of OA
loss of articular cartilage
remodeling of adjacent bone with new bone formation (osteophytes)
synobial membrane inflammation
Osteophytes
remodeling of adjacent bone with new bone formation
what is the onset of OA like
gradual onset, affects one or multiple joints, varied types of OA
Characteristics of OA
joint pain, hand deformities