Rheuma Flashcards

0
Q

Rash seen in Lyme disease

A

Erythema migrans

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1
Q

Most common form of arthritis in young sexually active persons

A

Gonococcal arthritis

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2
Q

Test for acute, disseminated or late Lyme disease if ELISA is indeterminate

A

Western blot

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3
Q

Treatment for late carditis or neurologic disease of Lyme disease

A

Ceftriaxone

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4
Q

Most important risk factor for developing primary OA in men and women

A

Age

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5
Q

Joint involvement of OA where x-ray is not helpful and is more specifically diagnosed with clinical examination

A

Hand OA

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6
Q

Gold standard test for hip and knee OA

A

X-ray

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7
Q

First-line therapy for hip and knee OA

A

Acetaminophen

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8
Q

Most common cause of death in patients with RA

A

Coronary artery disease

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9
Q

Most common autoimmune disease associated with Sjögren syndrome

A

RA

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10
Q

Patients with Sjögren syndrome are predisposed to this malignancy

A

B cell lymphoma

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11
Q

Biopsy specimen used to establish diagnosis of Sjögren syndrome

A

Labial minor salivary gland

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12
Q

Percentage of patients with psoriatic arthritis who exhibit joint before skin manifestations

A

15%

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13
Q

Most common pattern of joint involvement of psoriatic arthritis

A

Symmetric oligoarthritis

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14
Q

Psoriasis-like skin lesion on the palms and soles of patients with reactive arthritis

A

Keratoderma blenorrhagicum

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15
Q

Shallow, moist, serpiginous ulcers with raised borders on the glans penis of patients with reactive arthritis

A

Circinate balanitis

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16
Q

Common first-line DMARD for reactive arthritis that persists for more than 3-5 months

A

Sulfasalazine

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17
Q

Classic triad of reactive arthritis (found in only 1/3 of patients)

A

Arthritis, urethritis (or cervicitis), conjunctivitis

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18
Q

Most common extra-articular manifestation of ankylosing spondylitis

A

Acute anterior uveitis

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19
Q

Mainstay of management of ankylosing spondylitis

A

NSAIDs

20
Q

Percentage of patients with IBD who develop peripheral arthritis

A

20%

21
Q

Classic presentation of acute gouty attack that will not require synovial fluid analysis to make the diagnosis

A

Podagra

22
Q

Drugs that cause transplantation-associated gout

A

Calcineurin antagonists (cyclosporine)

23
Q

First-line therapy for acute gouty flare

A

NSAIDs

24
Q

Metabolic disorders that should be screened for in patients with CPDD who are <50 years old

A

Hemochromatosis
Hyperparathyroidism
Hypothyroidism
Gout

25
Q

Conditions associated with hypertrophic osteoarthropathy

A

Lung cancer, chronic pulmonary infections, right-to-left cardiac shunts

26
Q

Major cause of death in patients with SLE

A

Cardiovascular disease

27
Q

Primary cause of morbidity and mortality in patients with systemic sclerosis

A

Pulmonary disease

28
Q

Antibodies associated with mixed connective tissue disease

A

Anti-RNP antibodies

29
Q

Two signs virtually diagnostic of dermatomyositis

A

Gottron papules and heliotrope rash

30
Q

Definitive study for idiopathic inflammatory myopathies

A

Muscle biopsy

31
Q

First-line treatment for polymyositis or dermatomyositis

A

High-dose oral corticosteroid

32
Q

Vasculitis with skin lesions (red macules, palpable purpura, nodules, or ulcers), glomerulonephritis, and elevated serum aminotransferases

A

Cryoglobulinemic vasculitis

33
Q

Vasculitis with keratitis and acute hearing loss

A

Cogan syndrome

34
Q

Most common presenting feature of relapsing polychondritis

A

Auricular pain and swelling

35
Q

Diseases associated with saddle nose deformity

A

Relapsing polychondritis
Granulomatosis with polyangiitis
Syphilis

36
Q

Cause of back pain characterized by neurogenic claudication exacerbated by walking and spinal extension but improved by sitting and leaning forward

A

Spinal stenosis

37
Q

A wide-based gait and abnormal Romberg test is highly specific for this condition

A

Spinal stenosis

38
Q

Most common cause of knee pain in patients <45 years, especially women

A

Patellofemoral pain syndrome

39
Q

Diagnostic test for osteonecrosis of the hip

A

MRI

40
Q

Antibiotics associated with Achilles tendon rupture

A

Fluoroquinolones

41
Q

Most common cause of inferior heel pain

A

Plantar fasciitis

42
Q

First-line therapy for carpal tunnel syndrome

A

Splinting at night plus NSAIDs

43
Q

Most sensitive and specific imaging modality for complete or partial rotator cuff tears

A

MRI

but ultrasound is more cost effective

44
Q

Cornerstone of treatment for fibromyalgia

A

Nonpharmacologic therapy (regular aerobic exercise and cognitive behavioral therapy)

45
Q

First-line treatments of fibromyalgia

A

Centrally acting medications and graded exercise

46
Q

Effective treatments for pain in complex regional pain syndrome even in the absence of osteoporosis

A

Bisphosphonates

47
Q

Elevated levels of this protein are highly specific and reflect disease activity in adult-onset Still disease

A

Ferritin (levels >2500 ng/mL)

48
Q

First-line agents in management of adult-onset Still disease

A

NSAIDs