Rheuma Flashcards
Rash seen in Lyme disease
Erythema migrans
Most common form of arthritis in young sexually active persons
Gonococcal arthritis
Test for acute, disseminated or late Lyme disease if ELISA is indeterminate
Western blot
Treatment for late carditis or neurologic disease of Lyme disease
Ceftriaxone
Most important risk factor for developing primary OA in men and women
Age
Joint involvement of OA where x-ray is not helpful and is more specifically diagnosed with clinical examination
Hand OA
Gold standard test for hip and knee OA
X-ray
First-line therapy for hip and knee OA
Acetaminophen
Most common cause of death in patients with RA
Coronary artery disease
Most common autoimmune disease associated with Sjögren syndrome
RA
Patients with Sjögren syndrome are predisposed to this malignancy
B cell lymphoma
Biopsy specimen used to establish diagnosis of Sjögren syndrome
Labial minor salivary gland
Percentage of patients with psoriatic arthritis who exhibit joint before skin manifestations
15%
Most common pattern of joint involvement of psoriatic arthritis
Symmetric oligoarthritis
Psoriasis-like skin lesion on the palms and soles of patients with reactive arthritis
Keratoderma blenorrhagicum
Shallow, moist, serpiginous ulcers with raised borders on the glans penis of patients with reactive arthritis
Circinate balanitis
Common first-line DMARD for reactive arthritis that persists for more than 3-5 months
Sulfasalazine
Classic triad of reactive arthritis (found in only 1/3 of patients)
Arthritis, urethritis (or cervicitis), conjunctivitis
Most common extra-articular manifestation of ankylosing spondylitis
Acute anterior uveitis
Mainstay of management of ankylosing spondylitis
NSAIDs
Percentage of patients with IBD who develop peripheral arthritis
20%
Classic presentation of acute gouty attack that will not require synovial fluid analysis to make the diagnosis
Podagra
Drugs that cause transplantation-associated gout
Calcineurin antagonists (cyclosporine)
First-line therapy for acute gouty flare
NSAIDs
Metabolic disorders that should be screened for in patients with CPDD who are <50 years old
Hemochromatosis
Hyperparathyroidism
Hypothyroidism
Gout
Conditions associated with hypertrophic osteoarthropathy
Lung cancer, chronic pulmonary infections, right-to-left cardiac shunts
Major cause of death in patients with SLE
Cardiovascular disease
Primary cause of morbidity and mortality in patients with systemic sclerosis
Pulmonary disease
Antibodies associated with mixed connective tissue disease
Anti-RNP antibodies
Two signs virtually diagnostic of dermatomyositis
Gottron papules and heliotrope rash
Definitive study for idiopathic inflammatory myopathies
Muscle biopsy
First-line treatment for polymyositis or dermatomyositis
High-dose oral corticosteroid
Vasculitis with skin lesions (red macules, palpable purpura, nodules, or ulcers), glomerulonephritis, and elevated serum aminotransferases
Cryoglobulinemic vasculitis
Vasculitis with keratitis and acute hearing loss
Cogan syndrome
Most common presenting feature of relapsing polychondritis
Auricular pain and swelling
Diseases associated with saddle nose deformity
Relapsing polychondritis
Granulomatosis with polyangiitis
Syphilis
Cause of back pain characterized by neurogenic claudication exacerbated by walking and spinal extension but improved by sitting and leaning forward
Spinal stenosis
A wide-based gait and abnormal Romberg test is highly specific for this condition
Spinal stenosis
Most common cause of knee pain in patients <45 years, especially women
Patellofemoral pain syndrome
Diagnostic test for osteonecrosis of the hip
MRI
Antibiotics associated with Achilles tendon rupture
Fluoroquinolones
Most common cause of inferior heel pain
Plantar fasciitis
First-line therapy for carpal tunnel syndrome
Splinting at night plus NSAIDs
Most sensitive and specific imaging modality for complete or partial rotator cuff tears
MRI
but ultrasound is more cost effective
Cornerstone of treatment for fibromyalgia
Nonpharmacologic therapy (regular aerobic exercise and cognitive behavioral therapy)
First-line treatments of fibromyalgia
Centrally acting medications and graded exercise
Effective treatments for pain in complex regional pain syndrome even in the absence of osteoporosis
Bisphosphonates
Elevated levels of this protein are highly specific and reflect disease activity in adult-onset Still disease
Ferritin (levels >2500 ng/mL)
First-line agents in management of adult-onset Still disease
NSAIDs
