Dermatology Flashcards
Infectious agent associated with pityriasis rosea
Herpesvirus 6 or 7
Sexually transmitted infection that can mimic pityriasis rosea
Secondary syphilis
Herpes zoster infection involving the first division of the trigeminal nerve, which may include the tip of the nose
Zoster ophthalmicus
Vesicles in the ears, diminished taste on the anterior two thirds of the tongue, and ipsilateral facial paralysis
Ramsay Hunt syndrome
Treatment for herpes zoster should be given within this number of hours since lesion onset
72 hours
antivirals are used for zoster ophthalmicus even if more than 72 hours have elapsed
Treatment for herpes zoster
Valacyclovir or famciclovir for 7 days; gabapentin or amitriptyline for neuropathic pain
Skin finding that defines chronic eczema
Lichenification (exaggeration of skin markings, with skin thickening, scaling, and abnormal pigmentation)
Treatment for recalcitrant atopic eczema
Topical tacrolimus
Emollient that works by increasing water-holding capacity of the skin
Urea
Other emollients: petrolatum traps water in the skin; aqueous cream introduces water into the skin
Diagnosis: “acne,” with onset after age 18 years, erythematous lesions involving the central face with telangiectasias, pustules, and papules without comedones
Rosacea
Diagnosis: painful, recurrent, chronic, sterile abscesses; sinus tract formation; and scarring of the axillary, inguinal, perianal, and inframammary intertriginous areas
Hidradenitis suppurativa
Hallmark of acne
Comedones
Treatment for rosacea
Metronidazole gel, low-dose oral tetracycline, or erythromycin
Guttate psoriasis often develops after infection with this organism
Beta-hemolytic streptococcus
Indications for phototherapy in plaque or guttate psoriasis (3)
(1) Involvement of more than 5% of BSA, (2) inadequate response to topical medications, (3) intolerance to systemic therapy
Biologic that improves skin and joint symptoms in psoriasis
Etanercept
Erosion of normal-appearing skin by application of sliding pressure
Nikolsky sign
Ability to laterally extend bullae by applying gentle pressure
Asboe-Hansen sign
Erosion of normal-appearing skin by application of sliding pressure; seen in pemphigus vulgaris
Nikolsky sign
Ability to laterally extend bullae by applying gentle pressure; seen in pemphigus vulgaris
Asboe-Hansen sign
Deposits seen on skin biopsy of patients with pemphigus vulgaris
IgA (intercellular deposits at the epidermal surfaces)
Malignancies (2) commonly associated with paraneoplastic pemphigus
Lymphoma and chronic lymphocytic leukemia
Deposits seen on skin biopsy and immunofluorescence of patients with bullous pemphigoid
IgG (linear deposits at the basement membrane)
Condition associated with dermatitis herpetiformis
Celiac disease
