Rheuma 2 Flashcards

1
Q

Scleroderma forms

A

Systemic/Scleroderma

Diffuse cutaneous

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2
Q

Limited cutaneous scleroderma

A

CREST Syndrome

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3
Q

CREST Syndrome

A
Calcinosis cutis
Reynaud’s phenomenon
Esophageal dysmotility
Sclerodactyly
Telangiectasis
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4
Q

Most frequently involved organ in limited and diffuse cutaneous

A

Skin 90% and 100%
Raynaud 99 and 98
Esophageal involvemement 90 both

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5
Q

Clinical manifestation consistent with limited cutaneous systemic scleroderma

A

Sclerodactyly

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6
Q

Shawl sign

Heliotope rash

A

Dermatomyositis

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7
Q

Stiffness of a joint due to abnormal adhesion and rigidity of bones of joint

A

Ankylosis

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8
Q

Infalmmation of vertebrae

A

Spondylitis

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9
Q

Begins in 2nd and 3rd decade

M>F 2-3:1

A

Ankylosing spondylysis

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10
Q

AS and Reiter’s are associated with

A

HLA B27

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11
Q

AS manifestation

A

Dull pain in lumbar or gluteal region
Low back morning stiffness of up to few hours duration
Bony tenderness

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12
Q

Pain in AS

A

Improves with activity

Returns with inactivitg

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13
Q

Measures ability of px to flex lower back

A

Modified Schober’s

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14
Q

Modified Schober’s marker

A

L5

5cn below and 10cm above
Touch toes with knees straight

LOM in <5cm difference between 2 points

Restriction: distance bet two points do not inc by at least 5cm

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15
Q

Most serious complication in AS

A

Spinal fracture (cervical)

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16
Q

Extraarterial manifestation of AS

A

Anterior uveitis 40%
Inflammation of colon ileum
Psoariasis
Aortic insuff

17
Q

Dx of AS

A

Chronic > or equal to 3 months back pain should have 4 or more of these

Age below 49
Insidious
Improves with exercise
No improvement with rest
Pain at night with improvement upon getting up
18
Q

Earliest radiographic change in AS

A

Blurring of cortical margins of subchondral bone
Erosion pseudowidening of js
Sclerosis

19
Q

AS best visualized by

A

MRI

20
Q

AS tx

A

NSAIDs
Anti TNF alpha
Infliximab

21
Q

Surgical indication for AS

A

Severe hip joint arthritis

Pain and stiffness relieved by THA

22
Q

Acute nonpurulent reactive arthritis complicating an infection elsewhere

Triad

A

Reiter’s syndrome

Conjunctivitis
Arthritis
Nongonoccocal urethritis/cervicitis

23
Q

Reiter’s syndrome gene

A

HLA B27

60-85% positive

24
Q

Reiter’s bacteria

A

Salmonella
Chlamydia
Yersinia

25
Q

Reiter’s is presumed to be acquired

A

sexually esp if with new partner

26
Q

Inflammation of enthesis where tendon and ligaments insert to bone

A

Enthesitis

27
Q

Musculoskeletal manif of Reiters

A

Arthritis
Dactylitis (sausage digit)
Tendinitis and fasciitis
Spinal and LBP

28
Q

Urogenital manifestation of Reiters

A

Urethritis

Cervicitis

29
Q

Ocular manifestation of Reiter

A

Conjunctivitis

Anterior uveitis

30
Q

Mucocutaneous lesions in Reiters

A
Keratoderma blenorrhagica (vesicle -> hyperkeratotic) of soles and palms
Oral ulcer
31
Q

Oral apthuous ulcer

Genital ulcer

A

Behcet’s syndrome

32
Q

Circinate balanitis is found in

Onycholysis

A

Reiter’s

33
Q

Less frequent manifestation of reiterks

A

Aortic insufficiency

Cardiac manif

34
Q

Reiter’s tx

A

Indomethacin

If refractory

Azathioprine then Methotrexate

35
Q

Neutropenia
Splenomegaly
Nodular RA

A

Felty’s syndrome