Rheuma 2 Flashcards

1
Q

Scleroderma forms

A

Systemic/Scleroderma

Diffuse cutaneous

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2
Q

Limited cutaneous scleroderma

A

CREST Syndrome

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3
Q

CREST Syndrome

A
Calcinosis cutis
Reynaud’s phenomenon
Esophageal dysmotility
Sclerodactyly
Telangiectasis
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4
Q

Most frequently involved organ in limited and diffuse cutaneous

A

Skin 90% and 100%
Raynaud 99 and 98
Esophageal involvemement 90 both

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5
Q

Clinical manifestation consistent with limited cutaneous systemic scleroderma

A

Sclerodactyly

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6
Q

Shawl sign

Heliotope rash

A

Dermatomyositis

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7
Q

Stiffness of a joint due to abnormal adhesion and rigidity of bones of joint

A

Ankylosis

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8
Q

Infalmmation of vertebrae

A

Spondylitis

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9
Q

Begins in 2nd and 3rd decade

M>F 2-3:1

A

Ankylosing spondylysis

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10
Q

AS and Reiter’s are associated with

A

HLA B27

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11
Q

AS manifestation

A

Dull pain in lumbar or gluteal region
Low back morning stiffness of up to few hours duration
Bony tenderness

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12
Q

Pain in AS

A

Improves with activity

Returns with inactivitg

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13
Q

Measures ability of px to flex lower back

A

Modified Schober’s

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14
Q

Modified Schober’s marker

A

L5

5cn below and 10cm above
Touch toes with knees straight

LOM in <5cm difference between 2 points

Restriction: distance bet two points do not inc by at least 5cm

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15
Q

Most serious complication in AS

A

Spinal fracture (cervical)

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16
Q

Extraarterial manifestation of AS

A

Anterior uveitis 40%
Inflammation of colon ileum
Psoariasis
Aortic insuff

17
Q

Dx of AS

A

Chronic > or equal to 3 months back pain should have 4 or more of these

Age below 49
Insidious
Improves with exercise
No improvement with rest
Pain at night with improvement upon getting up
18
Q

Earliest radiographic change in AS

A

Blurring of cortical margins of subchondral bone
Erosion pseudowidening of js
Sclerosis

19
Q

AS best visualized by

20
Q

AS tx

A

NSAIDs
Anti TNF alpha
Infliximab

21
Q

Surgical indication for AS

A

Severe hip joint arthritis

Pain and stiffness relieved by THA

22
Q

Acute nonpurulent reactive arthritis complicating an infection elsewhere

Triad

A

Reiter’s syndrome

Conjunctivitis
Arthritis
Nongonoccocal urethritis/cervicitis

23
Q

Reiter’s syndrome gene

A

HLA B27

60-85% positive

24
Q

Reiter’s bacteria

A

Salmonella
Chlamydia
Yersinia

25
Reiter’s is presumed to be acquired
sexually esp if with new partner
26
Inflammation of enthesis where tendon and ligaments insert to bone
Enthesitis
27
Musculoskeletal manif of Reiters
Arthritis Dactylitis (sausage digit) Tendinitis and fasciitis Spinal and LBP
28
Urogenital manifestation of Reiters
Urethritis | Cervicitis
29
Ocular manifestation of Reiter
Conjunctivitis | Anterior uveitis
30
Mucocutaneous lesions in Reiters
``` Keratoderma blenorrhagica (vesicle -> hyperkeratotic) of soles and palms Oral ulcer ```
31
Oral apthuous ulcer | Genital ulcer
Behcet’s syndrome
32
Circinate balanitis is found in | Onycholysis
Reiter’s
33
Less frequent manifestation of reiterks
Aortic insufficiency | Cardiac manif
34
Reiter’s tx
Indomethacin If refractory Azathioprine then Methotrexate
35
Neutropenia Splenomegaly Nodular RA
Felty’s syndrome