Infectious HIV Flashcards

1
Q

AIDS defining opportunistic illness

A
Candidiasis
Cervical CA
TB
Coccidiodomycosis
Cryptococcosis
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2
Q

Most common cause of HIV disease throughout world

A

HIV 1

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3
Q

Worldwide pandemic

A

HIV1 M group

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4
Q

RNA

reverse transcription of its RNA to DNA by enzyme reverse transcriptase

A

HIV

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5
Q

HIV high affinity binding responsible for helper function

A

CD4

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6
Q

Highest probability of acquiring HIV

A

Blood transfusion highest
Receptive anal intercourse
Needle sharing during injection drug use 63-%
Percutaneous needle stick 23

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7
Q

Most common mode of infection

A

Heterosexual transmission

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8
Q

Prevention of pneumocystis j

A

Trimethoprim

Sulfamethoxazole

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9
Q

Give trimethoprim-sulfamethoxazole 1 ds tablet qd PO in PCP if CD4 count

A

<200

Stop prophy if CD4 >200 after 3 mos

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10
Q

PCP hallmark

A

Profound hypoxemia

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11
Q

Mycobacterium avium complex CD4 <50 count give

A

Azithromycin 1200mg weekly PO

600 BID PO weekly

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12
Q

Most common opportunistic infection in HIV most severe

A

MAC

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13
Q

Most HIV pxs die with

A

PCP

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14
Q

DOC for toxoplasma gondii

Give prophy if

A

Pyrimethamine

CD4 <200

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15
Q

Varicella zoster

A

Azyclovir 800mg

Valacyclovir 1g PO

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16
Q

Herpes virus tx

CMV tx

A

Acyclovir

Gancyclovir

17
Q

Cryptococcus neoformans tx

A

Fluconazole 200mg/d PO

Stop prophy if CD4 >100
HIV RNA <500 copies

18
Q

H capsulatum tx

A

Itraconazole 200mg BID

19
Q

Acyclovir analog active against HSV and VZV esp in CMV

A

Gancyclovir

20
Q

Used in combi against HIV and active Hep B also for chronic Hep B

A

Lamivudine

21
Q

Most commonly used confirmatory test for HIV

A

Western blot

22
Q

Antiviral choice for treatment of HSV

23
Q

Most common type of immunoblastic lymphoma HIV

A

Large B cell

24
Q

Natural reservoir of HIV-1, most likely source of original human infection

A

Pan troglodytes troglodytes

25
AIDS defining opportunistic infection
Pneumocystosis Candidiasis Cryptoxoccosis NOT TOXOPLASMOSIS
26
MSM, chronic headache, seizure, oral ulcer, diarrhea, unexplained weight loss and whitish plaque on oral mucosa CD4 <100? PML
JC virus
27
HIV infected persons have this chance of acquiring active TB in their lifetime
10%