Infectious HIV

Question 1

AIDS defining opportunistic illness

Answer 1

Candidiasis
Cervical CA
TB
Coccidiodomycosis
Cryptococcosis

Question 2

Most common cause of HIV disease throughout world

Answer 2

HIV 1

Question 3

Worldwide pandemic

Answer 3

HIV1 M group

Question 4

RNA

reverse transcription of its RNA to DNA by enzyme reverse transcriptase

Answer 4

HIV

Question 5

HIV high affinity binding responsible for helper function

Answer 5

CD4

Question 6

Highest probability of acquiring HIV

Answer 6

Blood transfusion highest
Receptive anal intercourse
Needle sharing during injection drug use 63-%
Percutaneous needle stick 23

Question 7

Most common mode of infection

Answer 7

Heterosexual transmission

Question 8

Prevention of pneumocystis j

Answer 8

Trimethoprim

Sulfamethoxazole

Question 9

Give trimethoprim-sulfamethoxazole 1 ds tablet qd PO in PCP if CD4 count

Answer 9

<200

Stop prophy if CD4 >200 after 3 mos

Question 10

PCP hallmark

Answer 10

Profound hypoxemia

Question 11

Mycobacterium avium complex CD4 <50 count give

Answer 11

Azithromycin 1200mg weekly PO

600 BID PO weekly

Question 12

Most common opportunistic infection in HIV most severe

Answer 12

MAC

Question 13

Most HIV pxs die with

Answer 13

PCP

Question 14

DOC for toxoplasma gondii

Give prophy if

Answer 14

Pyrimethamine

CD4 <200

Question 15

Varicella zoster

Answer 15

Azyclovir 800mg

Valacyclovir 1g PO

Question 16

Herpes virus tx

CMV tx

Answer 16

Acyclovir

Gancyclovir

Question 17

Cryptococcus neoformans tx

Answer 17

Fluconazole 200mg/d PO

Stop prophy if CD4 >100
HIV RNA <500 copies

Question 18

H capsulatum tx

Answer 18

Itraconazole 200mg BID

Question 19

Acyclovir analog active against HSV and VZV esp in CMV

Answer 19

Gancyclovir

Question 20

Used in combi against HIV and active Hep B also for chronic Hep B

Answer 20

Lamivudine

Question 21

Most commonly used confirmatory test for HIV

Answer 21

Western blot

Question 22

Antiviral choice for treatment of HSV

Answer 22

Acyclovir

Question 23

Most common type of immunoblastic lymphoma HIV

Answer 23

Large B cell

Question 24

Natural reservoir of HIV-1, most likely source of original human infection

Answer 24

Pan troglodytes troglodytes

Question 25

AIDS defining opportunistic infection

Answer 25

Pneumocystosis
Candidiasis
Cryptoxoccosis

NOT TOXOPLASMOSIS

Question 26

MSM, chronic headache, seizure, oral ulcer, diarrhea, unexplained weight loss and whitish plaque on oral mucosa

CD4 <100?

PML

Answer 26

JC virus

Question 27

HIV infected persons have this chance of acquiring active TB in their lifetime

Answer 27

10%