Revision Quiz Flashcards
The bioavailability of a drug is the fraction of an oral dose that
Reaches systemic
What is Phase 1 drug metabolism?
drug inactivation by liver
Which of these best describes Phase 1 drug metabolism??
1) drug inactivation by liver
2) drug conjugation by kidney
3) drug conjugation by liver
4) drug inactivation by GI tract
Drug inactivation by Liver
How does the kidney handle lipid soluble drugs compared to a water soluble drug?
Passive Reabsorption
Water soluble won’t be reabsorbed
Which drug would you you first prescribe to relieve acute asthma symptoms?
Salbutamol
Fluticasone
Prednisolone
Formoterol
Salbutamol
Which drug delivered by metered dose aerosol is prescribed for maintenance asthma therapy?
1) Terbutaline
2) Montelukast
3) Prednisolone
4) Fluticasone
Fluticasone
Preventer to reduce acute attacks
Metabolised First Pass
No systemic effect like steroid
Which adverse effect would you NOT expect to follow chronic treatment with Prednisolone?
1) Osteoporosis
2) Hypotension
3) Diabetes
4) Adrenal Suppression
Hypotension
Which antibiotic inhibits crosslinking of the peptidoglycan layer in the bacterial wall?
Metronidazole
Amoxicillin
Clarithromycin
Doxycycline
Amoxicillin
Which antibiotic would infection be resistant to?
44 year old man needs antibiotic treatment for injection with penicillin-ase producing Staph Aureus
Flucloxacillin
Amoxicillin
Co-Amoxicillin
Vancomycin
Amoxicillin
Which antibiotic would you use to treat uncomplicated UTI in young pregnant patient?
Trimethoprim
Nitrofuantoin
Amoxicillin
Gentamicin
Amoxicillin
Renal failure and deafness are adverse effects of which antibiotics??
Co-amoxiclav
Gentamicin
Doxycycline
Metronidazole
Gentamicin
Which drug group is prescribed for Afro-Caribbean man 68yrs with untreated mild hypertension
Thiazide Diuretic
Calcium Antagonist
ACE Inhibitor
B-adrenoreceptor antagonist
CALCIUM ANTAGONIST
How B-blockers reduce oxygen demand heart in treatment of Anginal pain
Reduce myocardial contracily
Reduce sytemic blood pressure
Increase venous capacitance
Reduce Heart Rate
Reduce myocardial contractility
Reduce sytemic blood pressure
Which route to administer nitrates in acute relief of angina pain
Skin patches
Sublingual tablets
Ointment
Sustained relase oral solution
Sub lingual tablets
Which B-blocker prescribed for Chronic heart failure in a patient 75+yrs
Atenolol
Nebivolol
Carvedilol
Bisoprolol
Nebivolol
What is potential adverse effect of non-selcteve B-blocker???
Tachycardia
Hypokalaemia
Dry Mouth
Bronchoconstriction
Bronchoconstriction
Which cardiac arrhythmia can be treated by adenosine, verapamil & digoxi
Which cardiac arrhythmia could be treated by adenosine, verapamil & digoxin
Ventricular Tachy
Supraventricular Tachy
Sinus Brady
Supraventricular tachy
Drugs work on AV node
Which anti-arrhythmic drug is most likely to produce heart block adverse effect
Propanolol
Amiodarone
Verapamil
Lidocaine
Verapamil
Which of following drugs can be used to treat DVT?
Dalteparin, low MW heparin
Atorvastin which reduc3es plams cholsetrol
Aspirin, COX inhibtor
Clopidogrel, purine receptor antagonist
Dalteparin
Statins inhibit which enzyme to reduce plasma cholesterol
Cyclo-oxygenase
HMG CoA reducatase
Vitamink K Epoxide reductase
Plasmin
MHG CoA reductase
Daily dose of Aspirin used in the prevention of secondary heart attack?
300mg
7.5G
600mg
75mg
75mg
