Revision Quiz

Question 1

The bioavailability of a drug is the fraction of an oral dose that

Answer 1

Reaches systemic

Question 2

What is Phase 1 drug metabolism?

Answer 2

drug inactivation by liver

Question 3

Which of these best describes Phase 1 drug metabolism??
1) drug inactivation by liver
2) drug conjugation by kidney
3) drug conjugation by liver
4) drug inactivation by GI tract

Answer 3

Drug inactivation by Liver

Question 4

How does the kidney handle lipid soluble drugs compared to a water soluble drug?

Answer 4

Passive Reabsorption
Water soluble won’t be reabsorbed

Question 5

Which drug would you you first prescribe to relieve acute asthma symptoms?

Salbutamol
Fluticasone
Prednisolone
Formoterol

Answer 5

Salbutamol

Question 6

Which drug delivered by metered dose aerosol is prescribed for maintenance asthma therapy?

1) Terbutaline
2) Montelukast
3) Prednisolone
4) Fluticasone

Answer 6

Fluticasone

Preventer to reduce acute attacks
Metabolised First Pass
No systemic effect like steroid

Question 7

Which adverse effect would you NOT expect to follow chronic treatment with Prednisolone?

1) Osteoporosis
2) Hypotension
3) Diabetes
4) Adrenal Suppression

Answer 7

Hypotension

Question 8

Which antibiotic inhibits crosslinking of the peptidoglycan layer in the bacterial wall?

Metronidazole
Amoxicillin
Clarithromycin
Doxycycline

Answer 8

Amoxicillin

Question 9

Which antibiotic would infection be resistant to?

44 year old man needs antibiotic treatment for injection with penicillin-ase producing Staph Aureus

Flucloxacillin
Amoxicillin
Co-Amoxicillin
Vancomycin

Answer 9

Amoxicillin

Question 10

Which antibiotic would you use to treat uncomplicated UTI in young pregnant patient?

Trimethoprim
Nitrofuantoin
Amoxicillin
Gentamicin

Answer 10

Amoxicillin

Question 11

Renal failure and deafness are adverse effects of which antibiotics??

Co-amoxiclav
Gentamicin
Doxycycline
Metronidazole

Answer 11

Gentamicin

Question 12

Which drug group is prescribed for Afro-Caribbean man 68yrs with untreated mild hypertension
Thiazide Diuretic
Calcium Antagonist
ACE Inhibitor
B-adrenoreceptor antagonist

Answer 12

CALCIUM ANTAGONIST

Question 13

How B-blockers reduce oxygen demand heart in treatment of Anginal pain

Reduce myocardial contracily
Reduce sytemic blood pressure
Increase venous capacitance
Reduce Heart Rate

Answer 13

Reduce myocardial contractility
Reduce sytemic blood pressure

Question 14

Which route to administer nitrates in acute relief of angina pain

Skin patches
Sublingual tablets
Ointment
Sustained relase oral solution

Answer 14

Sub lingual tablets

Question 15

Which B-blocker prescribed for Chronic heart failure in a patient 75+yrs

Atenolol
Nebivolol
Carvedilol
Bisoprolol

Answer 15

Nebivolol

Question 16

What is potential adverse effect of non-selcteve B-blocker???

Tachycardia
Hypokalaemia
Dry Mouth
Bronchoconstriction

Answer 16

Bronchoconstriction

Question 17

Which cardiac arrhythmia can be treated by adenosine, verapamil & digoxi

Which cardiac arrhythmia could be treated by adenosine, verapamil & digoxin

Ventricular Tachy
Supraventricular Tachy
Sinus Brady

Answer 17

Supraventricular tachy

Drugs work on AV node

Question 18

Which anti-arrhythmic drug is most likely to produce heart block adverse effect

Propanolol
Amiodarone
Verapamil
Lidocaine

Answer 18

Verapamil

Question 19

Which of following drugs can be used to treat DVT?

Dalteparin, low MW heparin
Atorvastin which reduc3es plams cholsetrol
Aspirin, COX inhibtor
Clopidogrel, purine receptor antagonist

Answer 19

Dalteparin

Question 20

Statins inhibit which enzyme to reduce plasma cholesterol

Cyclo-oxygenase
HMG CoA reducatase
Vitamink K Epoxide reductase
Plasmin

Answer 20

MHG CoA reductase

Question 21

Daily dose of Aspirin used in the prevention of secondary heart attack?

300mg
7.5G
600mg
75mg

Answer 21

75mg