Antihypertensives

Question 1

Propranolol is an antagonist if which peripheral receptor?

Answer 1

Beta adrenoreceptor

Beta blocker -olol prefix

Question 2

What is 1st line drug for hypertension treatment in 40yr Caucasian?

Answer 2

Losartan
Angiotensin Receptor Blocker
ARB/ACE
CCB
DIURETIC

Question 3

What ion channel is inhibited by Bendroflumethiazide in hypertension treatment?

Answer 3

Na/Cl Symporter from lumen side
Diuretic

Question 4

Bisoprolol is antagonist f which peripheral receptor?

Answer 4

Beta Receptor

Beta blockers -olol prefix

Question 5

MOA of ACE inhibitors

Answer 5

Inhibits conversion Angio 1 >Angio 2
Decreased Angio 2> decreased aldosterone
Increases Bradykinin

Question 6

ARB reduce circulating levels of which adrenal hormone???

Answer 6

Aldosterone suppressed

Question 7

Where is receptor for Aldosterone antagonist Spironolactone?

Answer 7

Cell cytoplasm

Question 8

What Cardiovascular drug causes flushing, oedema and postural hypertension?

Answer 8

Amlodipine

Vasodilator reduces peripheral resistance, influences movement of capillary fluid

Question 9

What adverse effects is less likely ARBS than with ARBs?

Answer 9

Cough
Increased bradykinin >Cough

Question 10

What is 1st line treatment for Afro-Caribbean origin?

Answer 10

Amlodipine

Calcium Channel Blocker

Question 11

What is most common adverse effect of Propranolol?

Answer 11

Fatigue-

Beta blocker work on sympathetic NS
Slow down body