Revision Flashcards
What kind of cancer is gastric cancer ?
AdenocarcinomA
Colorectal cancer
Risk Factors
Polyps
Lack of fibre - faster transfer time
Bile salts remain
WhAt is gastritis ?
Irritating if gastric mucosa
NSAIDs can irritate
Helicobacter pylori
3 causes
- intrinsic factor
Peptic Ulcers / duodenal
Breakdown of mucosa
Increased acid secretion
Bleeding - iron deficient anemia
How is ammonia broken down
Into Urea (amino acid ) Hydrogen Creatinine Urobilin Uric acid
Where does tubular reavosrpion take place ?
Proximal convuluted tubule
Control of salt . Hormones ?
AdH
Made in hypothalamus
Released from posterior pituitary
Kidneys have high oSmotic pressure for water re absorption
MaintIn sAlt and urea
Aldosterone
Causes re absorption of sodium
Increases activity of sodium pump / exchange with potassium in distal convoluted tubule
Releases via - reenin
Produced by fall in blood volume
AdH release ?
Triggered by oSmotic pressure
Acidosis effect
Alkalosis effect
Acidosis suppressed nervous system
Alkalosis increases nervous system - convulsions etc
Respiratory alkalosis - increased contraction
Renal compensation -
Respirator acidosis
Neural
Metabolic - kidney disease
Diabetes
IncrrSed ventilation
Metabolic alkalosis
Vomiting
Alkaline drugs
Kidneys cause of pre renal failure ?
Post renal failure
Fall in blood volume
DiareeH
Renal artery damage
Embolism
Kidney damage - glomerulitis? Problems with the vessels
Post renal -
Obstruction -stones / Tumor
Could be from bladder / prostate / urethra
Chronic renal failure ?
Causes by diabetes
Anemia can occur
Hypertension
Renal osteodytrophy
Nephrotic syndrome - key sign
Albumin in urine
Haemoturia
AssociAted with glomerula disease
Kidney Cancers ?
In children - nephroblastoma
Transitional cell carcinomas - pelvis/ kidney
Renal cell carcinoma - mostly elderly
Assc. Obesity
Hypertension
Smoking
Urinary cancers ?
Transitional cell carcinoma
Smoking
Signs ?
Bleeding.
Mestastasises - lymph nodes liver / bone
Pyelonephritis
Bacterial infection in kidney
Haemotogenous spread
Septicemia
Bacterial endo carcitis
Defective valves in the heart
Bacteria-
Urinary tract
Pressure on bladder / prostate infection
Backflow
Damage to glomeruli
Caused by diabetes