Review Questions and HPV

Question 1

What causes HPV ?

Answer 1

HPV gaines access through basal keratinocytes through minor ebrasions.

Enters between L1 and L2 proteins.

Virus replicates in the nucleus

The infected cell divides and the virus spreads laterallu then upward into the infected epithelium

Question 2

What is this ?

Answer 2

HPV-1 Volar Aspects of palms soles and tips of fingers and toes.

Question 3

What is this ?

Answer 3

HPV 2, 4 Verracus papules on glaberous skin

Question 4

What is this ?

Answer 4

HPV 3, 10

Verrucra Plana- slightly elevated flesh colored papules. Slightly keratotic

Question 5

What in the FUCKKKK is this ?

Answer 5

HPV 6 and 11 cause 90% of genital warts

Question 6

What is this histology ?

Answer 6

Viral Whart

Hyperkeratosis, Papillomatosis, Hypergranulosis

Vacuolated keratinic nucleocytes with pknotic raisen nuclei

Question 7

What does the bivalent vaccine protect from ?

What does guardacil protect from ?

Answer 7

HPV 16 and 18

HPV 6, 11, 16, 18

Question 8

What is this ?

Answer 8

Mussculosum contageosum

Question 9

What is this disease and why ?

Answer 9

Mussculosum contageosum. There are intrakerratinocyte inclusions. Which are called Henderson Paterson bodies. They are intracytoplasmic body inclusions

Question 10

What is this ?

Answer 10

Impetigo - usually infects the face of young children. Can be caused by S. Areus or S. Pyrogenes. The honey crust gives it away

Honey badger got impetigo.. now he gives a fuck

Question 11

What is this ?

Answer 11

Folliculitis

A superficial infection of the hair follicles that generates pus

Question 12

What is wrong with this kiddo ?

Answer 12

Staph Toxic Shock Syndrome

Exotoxin binds to desmogelin 1 and cleaves resulting in a loss of cell cell adhesion

Generalized errhythemia and desquamation of the epithelium

Question 13

And the second most disgusting picture of the block goes to ….. ?

Answer 13

HPV-6 - Genital Wart.

Remember that 90% of all genital warts are caused by HPV-6 and HPV-11

Question 14

What is this ?

Answer 14

Tinea Unguinum or oncchymoses is an infection of the nail plate or bed

This leads to nail bed deformity (Onchydystrophy) or thickening (Hyperkeratosis)

Question 15

What is this ?

Answer 15

Abscess - this is a tender red errhythematous abscess on the leg

Question 16

What is this ?

Answer 16

Furuncle - this is an inflammed follicular based nodule with a center necrotic plug that must come loose .

There is crust on the surface

Question 17

What is this ?

Answer 17

Yup you guessed it. The herp

Question 18

Answer 18

Question 19

Whats wrong with this kid ?

Answer 19

Herpes Simplex Virus - naughty naughty

Question 20

What is this ?

Answer 20

VZV Shingles- notice the dermatomal distribution. Remember Alpha Herpes Viruses are dormant in the dorsal ganglia.

This is followed by a dermatomal vessicular erruption

Question 21

What is this ?

Answer 21

Basal cell Carcinoma- notice the rounded borders and the tengalectasis

Question 22

What is this ?

Answer 22

Molluscum Contageosum - smooth dome shaped umblicated papules

Question 23

What is this? Patient presents with this rash after a night in the hot tub with a prostitute 3 days ago

Answer 23

Hot Tub Folliculitis- Pseudomonas

Question 24

What is this ?

Answer 24

They were not labeled but these look like palmoplantar warts of HPV-1

Question 25

And in the final round of what dong is this ?

Answer 25

Looks like an allergic reaction to elastic or whatever underware he is wearing. Must be external because of the straight lines.

Question 26

What is this disease ?

Answer 26

Tinea Versicolor

Question 27

What is this ?

Answer 27

Spaghetti and Meatball Fungal culture of Tinea Versicolor. Short Hyphae are the meatballs and long hyphae are the spaghetti