Review Questions

Question 1

Eye is protected against infections by which of the following

a. the mucous membranes that cover their surface
b. the secretion of complement proteins
c. the release of slightly acidic secretions
d. the secretion of lysozyme onto their surface
e. interferons produced by immune cells

Answer 1

D. They eye is free of most micro-organisms. Blicking removed microbes, tears wash the surface and have alot of lysozymes

Question 2

Which statement about the complement system is true?

a. These proteins are involved in innate immunity and not acquired immunity.
b. These proteins are secreted by cytotoxic T cells and other CD8 cells.
c. This group of proteins includes interferons and interleukins.
d. These proteins are one group of antimicrobial proteins acting together in cascade
fashion.
e. These proteins act individually to attack and lyse microbes.

Answer 2

D

Complement is a system of plasma proteins that can be activated directly by pathogens or indirectly by pathogen‐bound antibody, leading to a cascade of reactions that occurs on the surface of pathogens and generates active components with various effector functions.

Question 3

Which of the following is most likely to be recognized by a particular TLR that defends against some viruses?

a. lipopolysaccharides
b. double‐stranded DNA
c. double‐stranded RNA
d. glycoproteins
e. phospholipids

Answer 3

C.

Induction of antiviral innate immune responses depends on a family of innate immune receptors, the Toll‐like receptors (TLR). TLR mediate the antiviral immune responses by recognizing virus infection, activating signaling pathways and inducing the production of antiviral cytokines and chemokines. ssRNA and dsRNA viruses can be recognized by TLR7/8 and TLR3, respectively.