Abbreviations to remember Flashcards
Hematopoietic stem cells
HSC
PPSC
Common lymphoid progenitor
CLP
CFU-L
Common myeloid progenitor
CMP
CFU-GEMM
Those in the lymphoid lineage
- Pre-NK cells; go into blood become NK cells; go into CT; stay NK cells
- Pre-T cells; go into blood become T-cells; go to CT; stay T-cells
- Pre-B cells; go into blood become B-cell; in the CT, they can remain B-cells or form plasma cells.
Granulocyte-monocyte progenitor
GMP
CFU-GM
Megakaryocyte/erythrocyte progenitors
MEP
Megakarytocyte progenitor
MKP
CFU-Meg
Erythrocyte progenitor
ErP
CFU-E
CMP (CFU-GEMM) lineage
CMP (CFU-GEMM) will then become:
- GMP/ CFU-GMP (granulocyte-monocyte progenitor)
- MEP (megakaryocyte- erythrocyte progenitor)
MEP lineage
- MKP (CFU-Meg)- megakaryocyte progenitor–> megakaryoblast–> megakaryocyte all in the bone marrow and then release platelets into the blood
- ErP (CFU-E) erythrocyte progenitors–> proerythroblast–> orthochromatophilic erythroblast and then become RBC in the blood.
What are platelets made from?
Megakaryocytes
which are made from megakaryoblasts- MKP/CFU-Meg
What do GMP/CFU-GM produce?
- Prodendritic cell (pro-DC)
- Neutrophil progenitor (NoP/CFU-G)
- Basophil/mast cell progenitor (BMCP)
- Eosinophil progenitor (EoP/CFU-Eo)
- Monocyte progenitor (MoP/CFU-M)
ProDC
Prodendritic cell will go into the CT and become a dendritic cell
NoP/CFU-G
Neutrophil progenitor
Will go into the blood and become a neutrophil and remains a neutrophil in the CT
BMCP
Basophil/mast cell progenitor will create
- Basophil progenitors (BaP/CFU-Ba ) in the bone marrow. They will become basophils in the blood and remain in the blood
- Mast cell progenitors (MCP) are made in CT and become mast cells in the CT
EoP/CFU-Eo
Eosinophil progenitors become eosinophils in the blood and remain them in the CT
MoP/CFU-M
Become monocytes in the blood and become macrophages in the CT
Neutriohil progenitor
NoP
CFU-G