Review of Genetics Flashcards

1
Q

This is the study of inheritance or transmission of characteristics?

A

genetics

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2
Q

TRUE OR FALSE:

There’s a possibility to produce new alleles during inheritance

A

TRUE

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3
Q

The visual characteristic of an individual is called ________________

A

Phenotype

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4
Q

TRUE OR FALSE:

Phenotype depends on genotype on what to express

A

TRUE

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5
Q

Before the gene is expressed, to what substance does DNA should be transformed?

A

Protein/glycoprotein

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6
Q

This is the group of related red cell antigens

A

Blood group system

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7
Q

According to Harmening, the total number of BGS is ________ and for Howard there is __________

A

30, 36

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8
Q

This is the committe that is responsible for the nomenclature of RBC surface Ags

A

International society of blood transfusion

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9
Q

Major BGS’ ISBT number is from ______________

A

001-010

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10
Q

It is the basic unit of inheritance

A

Genes

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11
Q

This structure contains DNA that is formed by coiled chromatin fibers

A

Chromosome

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12
Q

This is a long strand of DNA that coiled up together with histones

A

Chromosome

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13
Q

There are two types of chromosomes: ___________

A

Autosomal or somatic (22pairs) and sex chromosome (1pair)

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14
Q

Trisomy occurs because of ___________

A

excess chromosome

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15
Q

What are Mendel’s law of inheritance?

A

Law of independent segregation and law of independent assortment

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16
Q

Who is the Father of Genetics?

A

Gregor Mendel

17
Q

This Mendel’s law states that genes for different traits are inherited separately from each other

A

Law of independent assortment

18
Q

This is used to calculate the frequency of the resulting genotypes and phenotypes

A

Punett Square

19
Q

What are the genotypes of A1 phenotype?

A

A1A1, A10, A1A2

20
Q

This is the alternative form of gene

A

Allele

21
Q

This is the portion of the chromosome that codes for the trait

A

Alleles

22
Q

This is the opposite of a gene

A

Antithetical

23
Q

What is polymorphic gene?

A

A genetic system that expresses multiple products

24
Q

TRUE OR FALSE:

Twins have the same polymorphic genes

A

FALSE

25
Q

This is the product that is always expressed whenever present

A

Dominant gene

26
Q

this is the product that will be only expressed if inherited in homozygous manner

A

Recessie gene

27
Q

In dosage effect , stronger agglutination is observed if gene is expressed by _____________

A

homozygous genes

28
Q

What are the examples of BGS who posses dosage effect?

A

MNS, Kidd, Duffy, Rh

29
Q

Which pattern inheritance wherein the carrier is the males/father?

A

Sex/X-linked dominant

30
Q

Which pattern inheritance wherein the carrier is the females/mother?

A

Sex/X-linked dominant

31
Q

Which pattern inheritance wherein the father transmits trait to daughter?

A

X-linked dominant

32
Q

Which pattern inheritance wherein the mother transmits trait to son?

A

X-linked recessive

33
Q

TRUE OR FALSE:

Autosomal dominant can affect all members of the family

A

TRUE

34
Q

What are null phenotypes?

A

phenotype where it lacks expression of red cell Ag

35
Q

What is amorphic/silent gene?

A

Gene that expresses no product

36
Q

What is regulator or suppressor gene?

A

Gene that inhibits the expression of another gene

37
Q

TRUE OR FALSE:

O gene is a silent gene

A

TRUE - it has no Ag on surface

38
Q

This gene is the precursor gene for the formation of the ABO Ag

A

H gene