Review of Genetics Flashcards
This is the study of inheritance or transmission of characteristics?
genetics
TRUE OR FALSE:
There’s a possibility to produce new alleles during inheritance
TRUE
The visual characteristic of an individual is called ________________
Phenotype
TRUE OR FALSE:
Phenotype depends on genotype on what to express
TRUE
Before the gene is expressed, to what substance does DNA should be transformed?
Protein/glycoprotein
This is the group of related red cell antigens
Blood group system
According to Harmening, the total number of BGS is ________ and for Howard there is __________
30, 36
This is the committe that is responsible for the nomenclature of RBC surface Ags
International society of blood transfusion
Major BGS’ ISBT number is from ______________
001-010
It is the basic unit of inheritance
Genes
This structure contains DNA that is formed by coiled chromatin fibers
Chromosome
This is a long strand of DNA that coiled up together with histones
Chromosome
There are two types of chromosomes: ___________
Autosomal or somatic (22pairs) and sex chromosome (1pair)
Trisomy occurs because of ___________
excess chromosome
What are Mendel’s law of inheritance?
Law of independent segregation and law of independent assortment
Who is the Father of Genetics?
Gregor Mendel
This Mendel’s law states that genes for different traits are inherited separately from each other
Law of independent assortment
This is used to calculate the frequency of the resulting genotypes and phenotypes
Punett Square
What are the genotypes of A1 phenotype?
A1A1, A10, A1A2
This is the alternative form of gene
Allele
This is the portion of the chromosome that codes for the trait
Alleles
This is the opposite of a gene
Antithetical
What is polymorphic gene?
A genetic system that expresses multiple products
TRUE OR FALSE:
Twins have the same polymorphic genes
FALSE
This is the product that is always expressed whenever present
Dominant gene
this is the product that will be only expressed if inherited in homozygous manner
Recessie gene
In dosage effect , stronger agglutination is observed if gene is expressed by _____________
homozygous genes
What are the examples of BGS who posses dosage effect?
MNS, Kidd, Duffy, Rh
Which pattern inheritance wherein the carrier is the males/father?
Sex/X-linked dominant
Which pattern inheritance wherein the carrier is the females/mother?
Sex/X-linked dominant
Which pattern inheritance wherein the father transmits trait to daughter?
X-linked dominant
Which pattern inheritance wherein the mother transmits trait to son?
X-linked recessive
TRUE OR FALSE:
Autosomal dominant can affect all members of the family
TRUE
What are null phenotypes?
phenotype where it lacks expression of red cell Ag
What is amorphic/silent gene?
Gene that expresses no product
What is regulator or suppressor gene?
Gene that inhibits the expression of another gene
TRUE OR FALSE:
O gene is a silent gene
TRUE - it has no Ag on surface
This gene is the precursor gene for the formation of the ABO Ag
H gene
