Review of autonomics and hypothalamus Flashcards
blood flow to the skin as a (blank) reflex
local
A hot compress on a small area of skin causes local (blank) and (blank)
vasodilation and sweating
The reflex contraction of the bladder in response to stretch is another example of a (blank) reflex
local
The (blank) is a prominent intermediary for many local reflexes.
nucleus solitarius
What can exert its influences by way of direct connections to preganglionic neurons or through other brainstem reticular nuclei?
nucleus solitarious
What kidn of effects can the nucleus solitarious have?
hormonal and behavioral responses through the brainstem or visceral motor responses through the preganglionic neurons
What does the hypothalamus do?
receives input about the state of th ebody and reads thinks like body temp, levels of fatty acids and glucose, length of day, and levels of circulating hormones.
The hypothalamus, after receiving info about temp, FA, glucose, hormones, what does it do with this info?
has both direct and indirect connections to motor neurons by way of neural and humoral pathways
What happens if you cut the descending tract of the hypothalamus and reticular formation?
you get unregulated autonomic reflex
autonomic dysreflexia/hypereflexia, neurogenic bladder, hyperthermia
How do you get bladder contraction and voiding?
hypothalamus-> midbrain PAG-> pontine micturation center-> parasympathetics and somatic motor neurons
Are paraysmpathetics cholinergic or adrenergic?
cholinergic
Are preganglionic sympathetics cholinergic and adrenergic?
cholinergic
Are postganglionic sympathetics with the exception of sweat glands are (blank).
adrenergic
Massive response as seen in elevated body temp is via (blank)
cortical control (all preganglionic involved in sweating and vasodilation will be involved)
If you cut all cortical control to the bladder, will the bladder still contract?
yes via the local reflex (neurogenic reflex of bladder)
Which 2 cranial nerves have a lot of input to the nucleus solitarius?
CN 9 and CN 10
What is the pathway that runs from the brainstem to the cortex and is it myelinated?
medial forebrain bundles
it is unmyelinated and does NOT go to thalamus
What is associated with control of autonomics and uses monoamines as NT’s (dopamine, serotonin etc.)?
medial forebrain bundles
What is the reflex pathway for viscera?
visceral sensory input to preganglionic neurons
In order to reach the cortex, the nucleus solitarius must communicate to the (blank) or (blank)
hypothalamus
parabrachial nucles
WHat will happen to your bladder if you lose your cortex?
bladder will still contract but not at right time
What will happen to your bladder if you lose the hypothalamus?
bladder will contract but will be activated by ANY stretch
What will happen to your bladder if you have a lesion at the lower center (LMN)?
the bladder will no longer contract (flaccid atonic bladder) and will cause retention and at some point the bladder will have so much pressure that their will be dribbling
Damage to UMN results in (blank) bladder. Damage to LMN results in (blank) bladder.
reflexive (spastic)
flaccid or atonic
What are the three afferents to the hypothalamus?
hippocampus, amygdala, brainstem
What is involved in the consolidation of memories?
fornix, hippocampus and mammilary bodies.
What gives affarents to the fornix to the mamillary bodies?
hippocampus
How does the amygdala transmit its affarents to the hypothalamus?
via the stria terminalis which passes up behing the thalamus and goes to the anterior nuclear group of the hypothalamus
How does the cortex and brainstem send afferents to the hypothalamus?
Via the MFB
a birdirectional pathway that runs from brainstem through the hypothalamus to the medial and frontal cortex
(MOST IMPORTANT)
What is significant about the MFB?
it can bypass the thalamus
The hypothalamus sends infrmation to the cortex via (blank) main bundles.
3
What are the three main bundles from the hypothalamus to the cortex (efferents) and are they bidirectional?
the fornix (bidirectional)
MFB (bidirectional)
mammillothalamic (hippocampus to thalamus)
T/F
the hypothalamus has direct connections to the brainstem and spinal cord
T
How can the hypothalamus be divided?
into perivetricular, medial and lateral zones
What separates the medial and lateral zones of the thalamus?
the fornix
What does the medial zones of the hypothalamus contain?
well definied nuclei
What does the lateral zones of the hypothalamus contain?
large fiber bundles and the MFB
The (blank) is massive and comes from brainstem reticular formation and passes through the hypothalamus on the way to prefrontal cortical areas.
MFB
What does the MFB allow for?
the hypothalamus to influence cortical outputs
What are the there zones that the hypothalamus can be divided into from rostral to caudal?
optic chiasm
stalk of pituitary
mammillary bodies
(blank) and (blank) nuclei have neurons that have axons that go down into posterior pituitary and release oxytocin and ADH
paraventricular nuclei and supraoptic nuclei
(blank) nucleus plays a role in circadian rhythm
suprachiasmic
Lateral to the hypothalamic sulcus are more nuclei where (blank) passes through and is involved with regulating temperation
MFB
If you have legion in the lateral part of the supraoptic region what will happen?
loss of heat dissipation
The (blank) region is just behind the stalk of the pituitary showing the location of the arcute nucleus as part of the periventricular group
tuberal region
What does the tuberal region of the hypothalamus function in?
control in releasing factors an thus in control of the anterior pituitary
The (blank) nucleus is the main area for the production of releasing factors.
arcuate nucleus
The (blank) nucleus is considered to be a satiety center .
ventromedial nucleus
The (blank) area can be thought of as a hunger center.
lateral hypothalamic
The interactions between what 2 things is thought to regulate body weight and the set point theory of weight control?
ventromedial nucleus and lateral hypothalamic area
Lesions in the lateral hypothalamic area and ventromedial nucleus creates what problem?
major changes in levels of aggression
What is the mammillary nucleus involved in?
consolidation of memory
What does the posterior nucleus do?
temp. regulation, and heat production
Lateral part of hypothalamus does what for heat? posterior nucleus of hypothalamus does what for heat?
dissipates heat
makes heat
What part of the brain is linked to korsakoffs?
mammillary bodies
Animals with lesions in this area become hypothermic when they are placed in a room where the temp. isn’t controlled.
What area am i referring to?
the posterior nucleus
(blank) nucleus of the hypothalamus connects to motor neurons and preganglionics-> for shivering response and vasoconstriction of blood vessles does this by direct paths to (blank)
posterior nuclei
spinal cord
What do you find in the supraoptic area of the hypothalamus?
hypothalamic sulcus CN III praventricular nucleus suprachiasmatic nucleus supraoptic nucleus optic chiasm
What do you find in the tuberal region?
medial and lateral hypothalamic region
Medial-> MFB, Ventromedial nucleus, arcuate nucleus, fornix
Lateral-> MFB and fornix
What do you find in the mamillary area??
mammillary nuclei, CN III, fornix
and posterior nucleus