Review Flashcards
Discussion of code status with pt admitted to hospital is what type of preventive care
Quaternary prevention
What’s a type of primary prevention
Immunizations
What type of prevention is a Pap smear screening
Secondary prevention- strategies to promote early detection of disease
What type of prevention is mastectomy
Tertiary - aim to limit impact of established disease
What are the components of an intervention for treating tobacco use
Ask,advise,assess,assist,arrange
An immuno-compromised pt would like the pneumonia vaccine what is recommended
pCV 13 now and revaccinate with PPSV23 in 8 weeks
Screening of a hepatitis panel results with negative HBsAg, positive anti-HBs,negative anti-HBc what does this mean
Pt had hep B in the past and has passive immunity
Who should be screened for lung cancer
Adults 55-80 who have 30pk smoking history and currently smoke or quit with in past 15 years
Order Low dose CT chest
Women 50-74 should get screened how often for breast cancer
Biennial mammogram
Elevation in lead II, III and aVF indicate what type of MI
Inferior
Elevation in lead v3&v4 what type of MI
Anterior
Elevation in lead v1 V2and V3indicate MI where
Anteroseptal
Hgb levels
14-18 males
12-16 femals
HCT levels
Males: 40-54
Female 37-47
TIBC what is it and levels
Binding capacity of iron- increased means higher need for iron
Normal 250-450
Serum iron
50-150
MCV
Volume and size of erythrocyte
80-100
MCV
Mean corpuscular volume - average amount/weight of Hgb in a single erythrocyte
Normal 26-34
MCHC
Mean corpuscular hemoglobin concentration-average Hgb concentration of each RBC more accurate then MCH
Normal 32-36%
Low MCV anemias
Iron deficiency
Thalassemia
Microcytoc anemia
High MCV anemia
Macrocytic anemia
B12 or folate deficiency,alcoholism,liver failure and drug effects
Normocytic anemia
Anemia of chronic disease
Sickle cell
Renal failure
Blood loss
Hemolysis
The most common cause of anemia
Iron deficiency anemia
Causes of iron deficiency anemia
Blood loss
Inadequate iron intake
Impaired absorption of iron
What anemia may cause Pica
Iron deficiency anemia
Labs: low h/h, low serum ferritin, high TIBC and low MCV - what type of anemia
Iron deficiency
Labs: low h/h, low MCV, low MCHC, normal TIBC and decreased a Hgb chain
Thalassemia
Genetically inherited disorder in abnormal Hgb and microcytic and hypochromic anemia
Thalassemia
Who gets thalassemia
Mediterranean African middle eastern Indian and Asian
Most common type of thalassemia
Beta thalassemia
An adult with thalassemia has which type most likely
Thalassemia minor
One copy of beta chain
Mild anemia
A child has what type of thalassemia that is progressively severe
Thalassemia major/Cooleys Anemia
2 genes for beta
Can you administer iron in thalassemia
No contraindicated
Tx for thalassemia
No treatment for mild/moderate, RBC transfusion/splenectomy for severe forms
Pt with fatigue, tachycardia and glossitis with out neuro changes has anemia what type do you expect
Folic acid deficiency
Labs: low h/h, elevated MCV, normal MCHC, decreased serum folate
Anemia?
Folic acid deficient
Tx for folic acid deficiency anemia
Folate acid 1mg every day
High folate food/ bananas, peanut butter,fish, green leafy vegetables iron fortified breads and cereals
Anemia caused by deficiency of intrinsic factor
Pernicious anemia (b12)
Labs: low h:h, MCV increased, decreased b12
Anemia?
Pernicious anemia
What type of anemia is pernicious anemia
Macrocyctic normochromic
Tx for pernicious anemia
B12 100mcg IM daily x1 eeek (front load) then lifelong monthly
Most common anemia in elderly and hospitalized patients
Anemia of chronic disease
Labs: low h/h, MCV normal, MCHC normal, serum iron and TIBC low, high serum ferritin
Anemia chronic disease
Pt reports pain in chest and aching joints, upon assessment appears dehydrated you suspect sickle cell what is the treatment
Fluids
Analgesics
Oxygen
Genetic disorder results in deficiency of clotting factor VIII
Von willebrand disease
Tx for von willebrand disease
Desmopreasin
Recombinant von Willebrand factor/factor VIII concentration
Acute leukemia in adults with long term survival of 40%
Acute myelogenous leukemia (AML)
90% remission rate in children hallmark of disease is Pancytopenia with circulation of blasts
Acute Lymphocytic leukemia (ALL)
Most common leukemia in adults
Chronic lymphocytic leukemia (CLL)
Hallmark of this leukemia is lymphocytosis
CLL - chronic lymphocytic leukemia
What leukemia is Philadelphia chromosome seen in
Chronic myelogenous leukemia (CML)
Pt with fatigue weight loss and generalized lymphadenopathy - what do you suspect
Leukemia
Pt presents with low h/h, fatigue, glossitis and parenthesis - what anemia do you suspect
How do you treat
Pernicious anemia
B12 IM daily x 1week then monthly
How is leukemia confirmed
Bone marrow biopsy
Why give allopurinol to a pt undergoing chemotherapy
To reduce tumor lysis syndrome
Management of leukemia
Chemo
Bone marrow transplant
Control symptoms
What stage is lymphoma if you have enlarged lymph in neck and groin
Stage III- lymph involved on both sides of diphragm
Stage II lymphoma involves what
More than one lymph node group- confined to one side of diaphragm
Stage I lymphoma is dx how
Disease localized to one single lymph node
Pt has lymphoma that has spread to neck lymph nodes, the spleen and the liver - what stage is this
Stage III- involves liver or bone marrow
20 year old male presents with advanced stage lymphoma - what type is this most likely
Non-hodgkins
What finding would differentiate Hodgkin’s disease from non-hodgkins
Reed-stern berg cells
Manager of lymphoma
Radiation
Chemo
Bone marrow transplant
Management of ITP( idiopathic thrombocytopenia purpura)
May not need till PLT <20000
High dose corticosteroids
IV gamma globulin (preferred for HIV pt)
PLT transfusion
Mtg if DIC
Treat underlying cause
PLT Tx for thrombocytopenia, FFP to replace clotting factors, cryo for fibrinogen
Use heparin
Labs associated with DIC
Thrombocytopenia PLT <150000
Hypofibrinogenemia /fibrin <170
Decreased RBC
Increased fibrin degradation products. (FDP) >45 mcg/ml
Prolonged PT >19 seconds
Prolonged PTT >42 seconds
DDimer +
Difference in acute vs chronic pain
Acute <6 months
What to consider to treat bone pain with Mets
Biophosphonates
What is neuroleptic malignant syndrome
Toxic on antipsychotic or antidepressant like SSRI
Pt presents to ED with possible overdose he is vomiting with hyperthermia elevated LFTs and tinnitus what substance do you suspect
Aspirin
Pt presents to Ed with possible overdose s/s include nausea excessive salivation blurred vision with kiosks and bradycardia. What substance do you suspect
Organophsphate insecticide
Tx for insecticide (organophosphate) poisoning
Wash skin
Activated charcoal if swallowed
Atropine is drug of choice
Tx for serotonin syndrome
Dantrolene sodium
Clonazepan to treat rigor
Cooling blankets
What condition do you need to worry about developing with antidepressant toxicity
Seizures- treat with benzodiazepines IV
S/s antidepressant toxicity
Confused
Hallucinations
Urinary retention
Hypothermia
Hypotension
Tachycardia
Seizure
Tx for beta blocker overdose
Glucagon
Atropine as needed
Stabilize airway
Tx of ethylene glycol overs OPO se
Fomepizole (antizol)
Ethanol if fomepizole not AV
What indicates compartment syndrome and what is treatment
Pressure >30 mmHG
Delta pressure <=30
Fasciotomy
What is delta pressure
Difference in Diastolic BP and the intra-compartmental pressure - if less then 30 need fasciotomy
Pathogen and drug for endocarditis
Staphylococcus aureus
Vanco + ceftriaxone
Drug choice for peritonitis
Metronidazole plus 3rd gen. Cephalosporin or zosyn
Common pathogen cause acute otitis media sinusitis and bronchitis
S. Pneumoniae
Common pathogen of cellulitis and Tx
Staph. Aureus , group A strep
Cefazolim, Vanco, clindamycin, linezolid and dapto
Tx for transplant Pt that you think is rejecting organ
Immediate biopsy
What is most effective anti-rejection regimen
Triple therapy
Steriod- methyprednisolone or prednisone
Antimetabolite
Calcimeurin inhibitor or mTOR
Who gets shingrix
Shingles vaccine
Adults >=50- 2 doses with 2nd dose given 2-6 months after first
Rough flesh colored pink patches in sun exposed parts of body
Actinic keratoses
Firm irregular pPule or nodule that is keratitis and scaly bleedinh
Squamous cell carcinoma
Benign non painful beige or black plaques that are “stuck on”
Sevorrheic kerToses
No treatment or nitrogen removal
Most common skin cancer
Basal cell carcinoma
Tx of basal cell carcinoma
Shave/punch biopsy and surgical excision
Highest mortality rate of all skin cancers
Malignant melanoma
Most common type of headache
Tension headache
Headache effecting middle age men and often at night and unilateral
Cluster headache
Tx of cluster headache
100% oxygen
Sumatriptan 6mg SQ
Normal urine sodium
10-20 mEq/L
Normal serum osmolality
275/285 (2x Na)
What does high urine sodium usually indicate
Renal salt wasting a problem with kidney
What sodium defect usually occurs with extreme hyperlipidemia or hyperproteinemia
Isotonic hyponatremia
normal CVP
0-6
Normal PAP
15-25/5-15
normal PCWP
6-12
normal CO
4-8