Reverse Pharm Psych Flashcards
Mood elevation Decr. anxiety Sedation Behavioral disinhibition respiratory depression
Non spec depressant intox
anxiety
tremor
seizures
insomnia
non spec depressant with
Alcohol
Opioids
Barbituates
Benzodiazepines
depressants
Emotional lability, slurred speech ataxia coma blackouts
Lab values?
alcohol intox
Serum Gamma glutamyltransferase (sensitive indicator)
AST value is twice ALT
Mild: Similar to other depressants
Severe: autonomic hyperactivity
DTs
Treatment?
Alcohol withdraw
Treatment: Benzos
Euphoria, respiratory and CNS depression Decr. gag reflex pupillary constriction seizures (overdose)
Treatment:
Opiod intox
Naloxone, naltrexone
Sweating Dilated pupils Piloerection Fever Rhinorrhea Yawning Nausea Stomach cramps Diarrhea
Treatment:
Opiod with.
Long term support, methadone, buprenorphine
Low safety margin
Marked resp. depression
Treatment:
Barbituate intox
Symptom management
Delirium
Life threatening CV collapse
Barbituate withdraw.
Greater safety margin
Ataxia
Minor resp. depression
Treatment:
Benzo intox
Flumenazil (benzo receptor antagonist, but can precipitate seizures)
Sleep disturbance
depression
Rebound anxiety
Seizure
Benzo withdrawal
Mood elevation psychomotor agitation INsomnia Arrythmias tachycardia Anxiety
stim intox NS
“Post use crash”–>
depression
lethargy
weight gain
headache
Stim with. NS
Amphetamines
Cocaine
Caffeine
Nicotine
Stimulants
Euphoria Grandiosity Pupillary dilation prolonged wakefulness and attention hypertension tachycardia anorexia paranoia fever
severe: cardiac arrest, seizure
Amphet intox
Anhedonia
Incr. appetite
hypersomnolence
existential crisis
Amphet with
Impaired judgment pupillary dilation hallucinations (including tactile) paranoid ideation angina sudden cardiac death
Treatment?
Cocaine intox
Alpha blockers, benzos
Never beta blockers
Hypersomnolence
Malaise
severe psych craving
depression/suicidality
Cocaine withdraw
restlessness
Incr. diuresis
muscle twitching
Caffeine intox