Reversal agents Flashcards
1
Q
Heparin reversal?
A
Protamine
2
Q
protamine MOA?
A
binds heparin forming a stable compound without anticoagulant activity
3
Q
warfarin reversal for big bleeds?
A
PCC
4
Q
things that decrease warfarin levels?
A
ginseng, st johns wart, coq10
5
Q
things that increase warfarin levels?
A
vitamin E, kava kava, red yeast rice
6
Q
reversal for TPA?
A
aminocaproic acid or TXA
7
Q
MOA of TPA?
A
promotes plasminogen to plasmin which degrades fibrin