Reuma Flashcards

1
Q

Pruebas antes de iniciar biológicos o inhibidores de JAK

A

Mantoux + Rx tórax
Vacunación en orden (VHB, gripe, neumococo, dtp)
ECG
Serologías VHB y VHC

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2
Q

Efectoos secundarios metrotrexato

A

Hepatotóxico
Aplasia medular
Fibrosis pulmonar

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3
Q

Efectos secundarios inhibidores JAK

A

Aumento riesgo de trombos
Reactivación VVZ –> Vacuna recombinante :)
Tofacitinib –> aumento riesgo vascular y neoplasias

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4
Q

Efectos adversos biológicos e inhibidores de JAK

A

Infecciones, citopenias y elevación de transas

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5
Q

Efectos adversos leflunomida

A

Hepatotóxico
Teratógeno

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6
Q

Efectos adversos hidroxicloroquina

A

Ojo de buey –> controles oftalmológicos

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7
Q

Contraindicaciones biológicos e inhibidores de JAK

A

IC NYHA III-IV

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8
Q

Osteonecrosis mandibular

A

Bifosfonatos y denosumab

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9
Q

Contraindicaciones apremilast

A

AP psiquiátricos

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