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Restrictive lung disease table Flashcards

1
Q

idiopathic pulmonary fibrosis

  • age group
  • associated with what?
A

older pts >60

assoc. w/ tobacco use

aka UIP (usual interstitial pneumonia) = IPF

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2
Q

idiopathic pulmonary fibrosis

  • age group
  • associated with what?
A

older pts >60

assoc. w/ tobacco use

aka UIP (usual interstitial pneumonia) = IPF

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3
Q

Restrictive lung diseases are typically going to present with what?

A

DOE
crackles
cough clubbing

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4
Q

What lung disease is going to have honeycombing with ground glass infiltrates?

A

IPF aka UIP

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5
Q

Nonspecific interstitial pneumonia NSIP

  • age group
  • prognosis?
A

younger females

prognosis better than IPF

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6
Q

What are the FEV1/FVC ratios for restrictive lung diseases?

A

slightly >/= 0.8
In restrictive lung disease, the FEV1 and FVC are equally reduced, thus, the FEV1/FVC ratio should be approximately normal, or slightly increased

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7
Q

What are the FEV1/FVC ratios for Obstructive lung diseases?

A
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8
Q

3 general causes of restrictive lung diseases

A
  1. increase in elastic/connective tissue
  2. increase in lung water
  3. increase in surface tension
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9
Q

Restrictive lung diseases are typically going to present with what?

A

DOE
crackles
cough clubbing

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10
Q

What lung disease is going to have honeycombing with ground glass infiltrates?

A

IPF aka UIP

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11
Q

Nonspecific interstitial pneumonia NSIP

  • age group
  • prognosis?
A

younger females

prognosis better than IPF

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12
Q

Organizing pneumonia

  • Is it infectious?
  • histo pattern?
  • how do you treat it?
A

BOOP!
Non infectious: usually idiopathic secondary to CVD, drugs, HP, aspiration

  • Bilateral peripheral alveolar opacities “fuzzy nodules”
  • Intraluminal plugs of granulation tissue

Very steroid responsive

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13
Q

What are the FEV1/FVC ratios for Obstructive lung diseases?

A

↓↓

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14
Q

Eosinophilic pneumonia:

  • presentation
  • treatment?
A
  1. Acute eosinophilic pneumonia
    - mimics ARDS (sim. to acute interstitial pneumonia)
  2. Chronic eosinophilic pneumonia
    - more in nonsmokers and women

lots of eosinophilic infiltrates (chronic has fibrosis and macrophages)

steroid responsive

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15
Q

Which one is homogenous? IPD or NSIP?

A

NSIP - homogenous

IPF - heterogenous

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16
Q

smoking related interstitial lung diseases (ILD):

A
  1. respiratory bronchiolitis (RB-ILD)
  2. Desquamative interstitial pneumonia (DIP)
  3. Langerhans cell histocytosis (LCH)
17
Q

What lung disease presents with accumulation of “dusty brown” macrophages?

A

the smoking related ILDs:

  1. respiratory bronchiolitis (RB-ILD)
    - bronchiocentric macrophages
  2. Desquamative interstitial pneumonia (DIP)
    - macrophages filling distal airspaces
18
Q

What pathogen is most common in:
community acquired pneumonia, -give typical vs atypical ones.

hospital acquired pneumonia?

A

community acquired pneumonia?

  • Strep pneumoniae (typical)
  • Mycoplasma pneumoniae (walking - atypical), virus (atypical)

hospital acquired pneumonia?

  • Staph (bc they get it from the staff!) MRSA
  • SPACE
19
Q

Lymphoid interstitial pneumonia:

  • usually associated with?
  • radiology?
  • Histo?
  • treat?
A

usually associated with autoimmune diseases or immunodeficiency. Can transform to pneumonia.

  • centrilobular nodules
  • germinal centers
  • immunosuppression
20
Q

Eosinophilic pneumonia:

  • presentation
  • treatment?
A
  1. Acute eosinophilic pneumonia
    - mimics ARDS (sim. to acute interstitial pneumonia)
  2. Chronic eosinophilic pneumonia
    - more in nonsmokers and women

lots of eosinophilic infiltrates
steroid responsive

21
Q

Lymphangioleiomyomatosis

  • what is it?
  • what complications are common?
  • treatment?
A

cystic lung disease only in young women

pleural effusions, spontaneous pneumothorax

anti-estrogen therapy

22
Q

Hypersensitivity pneumonitis

  • what is it?
  • symptoms
  • radiology?
  • Histo?
A

immunologic response to inhaled antigen
(Acute and Chronic - just like eosinophilic P)

cough. DOE

upper lobe predominant

inflammation with poorly formed granulomas

23
Q

Sarcoidosis:

  • which organs most affected?
  • presentation?
  • do they have restrictive or obstructive pattern?
  • histo?
  • treatment?
A
  • Lungs, eyes, Skin
  • Lymphadenopathy, chest pain, cough, wheezing,
  • may be mixed pattern
  • non-caseating granuloma
  • treatment often not necessary
24
Q

What bacteria is most common in:
community acquired pneumonia?
hospital acquired pneumonia?

A

community acquired pneumonia?
- Strep pneumoniae

hospital acquired pneumonia?

  • Staph (bc they get it from the staff!) MRSA
  • SPACE
25
Q

If pt has sepsis, what should you be suspicious of? Describe its treatment.

A

> 50% of causes of ARDS result from sepsis

If ventilating the patient, make sure TIDAL VOL IS LOW - lungs are healing bro,

6 cc / bodyweight

Pulm (17 decks)

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