Resting Potential Generation

Question 1

An important slide to know

Question 2

What is the structure of voltage gated Na channels and how does Na enters the cell

Answer 2

It has 2 sites of entry/exit:

1. Activation gate
2. Inactivation gate

Na in a resting cell does not enter the cell from voltage gated Na channels since these channels are closed at the activation gate and open at the inactivation gate. Na enters the cell through the leak channels

Question 3

Answer 3

Question 4

What is the equation that can be used to find membrane potential using Na and K conductance and Eion

Answer 4

Question 5

What is he trying to explain here

Answer 5

Fractional conductance of Na increases during depolarization which causes the membrane potential to go high whereas the during repolarization the fractional conductance of K increases which causes the membrane potential to decrease

Question 6

What is the significance of the fact that if cell is only permeable to Na and K

Answer 6

Sum of their partial conductances equal to 1

Question 7

What is the relationship between conductance and resting membrane potential

Answer 7

Question 8

Answer 8