resting membrane potential Flashcards

1
Q

what is the resting membrane potential of a cell

A

the electrical potential difference across the plasma membrane when the cell is in a non-excited state

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2
Q

membrane potential [Vm] is determined by

A
  • distribution of ions intra and extracellularly

- variation on the membrane permeability to different ions

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3
Q

the resting potential of an average neuron

A

-70mV

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4
Q

diffusion potential

A

the voltage at which the electrostatic force on an ion is equal and opposite to the chemical force on the concentration gradient

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5
Q

electrochemical gradient- steady state

A
  • no net force, no net ion flow
  • no further change in ion conc at plasma membrane
  • no further change in charge distribution or membrane potential
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6
Q

when Vm>Ek

A
  • constant flow of ions across the plasma membrane
  • Na+ moves in and K+ moves out
  • the number of ions moved is very small
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7
Q

role of Na+/K+ -ATPase

A
  • to replenish K+ lost from the cell

- to remove Na+ accumulated within the cell

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8
Q

the sodium potassium pump

A
  • outer membrane of the cell
  • helps maintain cells membrane potential- maintains gradient
  • primary potassium pump
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