cell cycle and mitosis Flashcards
G0 phase
non-cyclers/period when cells express their differentiated function
G1-s phase transition
important control point determining whether or not the cell enters S phase
S phase
replication of DNA and RNA protein. the duplicated chromosomes are called sister chromatids.
G2 phase
final preparations for mitosis
prophase
chromatin condenses to form visible chromosomes. each chromosome is 2 sister chromatids joined at centromeres. centrioles duplicate, move to opposite poles, act as microtubule-organising centres (MOTs). microtubules form the mitotic spindle apparatus between the spindles
prometaphase
nucleoli regress and nuclear membranes disassemble. chromosomes move to equator and interact with microtubules. each pair of sister chromatids has an attachment site called a kinetochore, which attach to the spindle fibres
metaphase
equatorial region of cell forms metaphase plate, the chromosomes arrange on plate as 2 sister chromatids. spindle microtubules run to centromeres of sister chromatids and attached at kinetochores
anaphase
microtubules pull sister chromatids apart, which move to opposite poles of the cell
telophase
chromosomes reach poles and decondense. nuclear membrane reassembles. a cleavage furrow begins around the equator. spindle disappears. nucleoli reappear