meiosis Flashcards
stages of prophase 1
1) leptotene
2) zygotene
3) pachytene
4) diplotene
5) diakinesis
leptotene
chromatin condensed to form chromosomes which are not yet split into sister chromatids. chromomeres are visible along their line
zygotene
homologous chromosomes (maternal-paternal) pair together to form bivalents. chromosomes now split into sister chromatids and local sites of alignment [synapsis] develop between sister chromatids of homologous pairs
pachytene
synapsis is completed and ‘crossing over’ [chiasmata formation] occurs
diplotene
chromatids are held together by chiasmata as well as by the centromeres
diakinesis
chiasmata appear to begin to move along the chromatids [terminilisation]
metaphase 1
each bivalent has 2 centromeres which by chance arrange themselves on opposite sides of the metaphase plate. independent assortment occurs.
anaphase 1
chromosomes move to opposite sides of the cell
telophase 1
each daughter has half the number of chromosomes. the nuclear envelope may reassemble before prophase 2 of the second meiotic division
meiosis 2
these are morphologically similar to those seen in mitosis. centromeres not split at kinetochores and sister chromatids move to opposite poles . at the end of the 2 divisions, potentially 4 gametes are formed
numerical chromosome abnormality
too few or too many chromosomes
structural chromosome abnormality
the chromosome structure has been altered