Respiratory tract infections microbiology

Question 1

Whooping cough causative organism?

Answer 1

Bordatella pertussis

Question 2

Diagnosis of whooping cough?

Answer 2

Bacterial culture:
Pernasal swab (<21 days)
Culture (charcoal-blood agar)

PCR:
Pernasal culture

Question 3

Whooping cough treatment (<1/12)

Answer 3

Clarithromycin

Question 4

Whooping cough treatment (>1/12)

Answer 4

Clarithromycin/azithromycin

Question 5

Whooping cough treatment pregnancy

Answer 5

Erythromycin

Question 6

CAP treatment strep pneumoniae

Answer 6

5 day course of amoxicillin

Question 7

How to diagnose Legionella?

Answer 7

Legionella urinary antigen - detects serotype I only

PCR now available direct from sputum

Question 8

Treatment for legionella pneumonia

Answer 8

Clarithromycin, erythromycin

Quinolones (e.g. levofloxacin)

Question 9

Flu vaccine

Answer 9

Killed vaccine given to adults and children aged 6months to 2 years

Live attenuated vaccine given to children aged 2-17

Question 10

Lab confirmation of mycoplasma coxiella and chlamydia psittaci?

Answer 10

By serology -GOLD TOP CONTAINER

By virus detection - PCR on swabs/secretions

Question 11

What is Q fever

Answer 11

Pyrexia of unkown origin
Coxiella burnetii
Sheeps and goats

Question 12

Complication of Coxiella Burnetti/Q fever

Answer 12

Culture negative endocarditis

Question 13

Lab confirmation of bronchiolitis?

Answer 13

PCR on throat/pernasal swabs

Question 14

What is chlamydia trachomatis?

Answer 14

STI which can cause infantile pneumonia

Question 15

How do you diagnose chlamydia trachomatis?

Answer 15

PCR on urine of mother or pernasal/throat swabs of child