Respiratory Systems 18 - Exercise Test Flashcards

1
Q

What is the respiratory quotient (RQ)?

A

Carbon dioxide to oxygen ratio

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2
Q

List the RQ in different types of metabolism.

A
  • Lipids 0.70
  • Protein 0.82
  • Glucose 1.00
  • Anaerobic respiration >1.00
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3
Q

What is a MET?

A
  • 1 Metabolic Equivalent

- At rest, humans need 3.5ml/min/kg oxygen

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4
Q

What is the muscles response to exercise?

A
  • Stored energy is used for muscular contraction
  • Inorganic phosphates (ADP/creatine) drive oxidative phosphorylation
  • Oxygen consumption at the muscle increases (10-15 fold)
  • CO2 production initially slightly increases, and then rises to match O2
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5
Q

How does the heart respond to exercise?

A
  • First there is an increase in stroke volume, and then an increase in heart rate
  • This overall results in higher cardiac output (4-7 fold increase)
  • Stroke volume starts to decrease while heart rate is still increasing
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6
Q

How much oxygen can be extracted during exercise?

A

Up to 85%

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7
Q

How does ventilation-perfusion matching change due to exercise?

A
  • At rest ventilation-perfusion matching is not ideal

- In early exercise the ventilation-perfusion matching improves

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8
Q

In exercise, why does oxygen uptake at the tissues increase?

A
  • Higher concentration gradient (more oxygen in the blood)

- Bohr Effect - the oxygen dissociation curve shifts left, so more oxygen is released at the cells.

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9
Q

How does exercise affect blood pH?

A
  • Initially pH decreases due to lactate
  • Bicarbonate buffers this, as a result more CO2 is produced (isocapnic buffering)
  • H+ eventually exceeds HCO3- (ventilatory compensation point)
  • This causes hyperventillation (respiratory compensation)
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