Respiratory System and Body Cavity Flashcards

1
Q

How many body cavities are created after embryonic folding?

A

1

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2
Q

Where does the endodermal gut tube form?

A

In the centre (surrounded by visceral mesoderm)

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3
Q

What is the lining of the respiratory tube?

A

Derivative of endoderm

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4
Q

After how many does is the gut tube formed?

A

26

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5
Q

What is the gut tube in communication with?

A

Cavity of respiratory diverticulum

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6
Q

How does the gut tube and respiratory diverticulum separate?

A

There are pinch points at the junction between respiratory and oesophags which fuse and separate

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7
Q

What are the swellings called?

A

Laryngeal swellings

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8
Q

What does the foregut get split into?

A

Trachea and oesophagus

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9
Q

As the bronchial tree grows, what does it carry with it?

A

Layer of mesoderm

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10
Q

What is the lining of the bronchial tree?

A

Endoderm

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11
Q

How many lobes does the right lung bud have?

A

3

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12
Q

How many lobes does the left lung bud have?

A

2

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13
Q

What is a fistula?

A

Abnormal communication between 2 spaces

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14
Q

What is a blind end?

A

When there is no connection to the trachea (oesophageal atresia)

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15
Q

Describe the maturation of lungs in the embryonic period (26 days - 6 weeks)

A

Respiratory diverticulum forms and initial segments arise

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16
Q

Describe the maturation of lungs in the pseudoglandular period (6 - 16 weeks)

A

14 generations of branching occurs and terminal bronchioles arise

17
Q

Describe the maturation of lungs in the canalicular stage (16 - 28 weeks)

A

Terminal bronchioles give rise to 2-3 respiratory bronchioles which branch into 3-6 alveolar bronchioles

18
Q

Describe the maturation of lungs in the saccular stage (28 - 36 weeks)

A

Terminal sacs are formed and capillaries establish close contact with alveoli

19
Q

What are the airways lined with?

A

Endodermal lining (tall columnar cells)

20
Q

As alveoli develop, the cells lining the respiratory cells differentiate into what and why?

A

Squamous cells to minimise distance for oxygen and CO2 to diffuse across

21
Q

What cells form the blood-air barrier?

A

Squamous cells (type 1) and some cuboidal cells (type 2)

22
Q

What do type 2 cells do?

A

Produce surfactant which refuces surface tension

23
Q

Where does the septum transversum initially start off?

A

Very head end (cranial) of embryo

24
Q

What is located cranially to the heart tube?

A

Solid wedge of mesoderm

25
Q

What separates the thorax and abdomen?

A

Septum transversum (but does not reach posterior body wall)

26
Q

What are pericardio peritoneal canals?

A

Connecting space around the heart to the space around the peritoneal

27
Q

As the septum transversum migrates towards thorax, what does it take with it?

A

Phrenic nerve (C3,4,5)

28
Q

What organ forms in the septum transversum?

A

Liver

29
Q

How do the pericardio peritoneal canals close?

A

Outgrowths from posterior body wall (pleuroperitoneal fold) grows medially and anteriorly before fusing with septum transversum and mesoderm

30
Q

Where does the musculature for the diaphragm come from?

A

Septum transversum (innervated by phrenic nerve); ingrowth of body wall (local innervation)

31
Q

What is a hernia?

A

Something that buldges from one place into another

32
Q

What membrane is more likely to obtain a congenital diaphragmatic hernia?

A

Left pleuroperitoneal membrane (complete loss or thin membrane)

33
Q

What part of the thorax develops with the lungs?

A

Left and right pleural cavity

34
Q

What do the left and right pleural cavities contribute?

A

Cartilge and muscle to the lungs; covering layer of pleura

35
Q

What name is given to the growth that divides the body cavity into the heart (anterior) and lungs (posterior)

A

Transverse growth

36
Q

Describe what happens when the pleuroperitoneal folds migrate anteriorly

A

They pull a margin of the pleura cavirt posteriorly to surround the lungs