Respiratory System Flashcards
What is the air flow pathway?
Nasal cavity —> nasopharynx —> larynx —> trachea —> bronchi —> bronchioles —> terminal bronchioles —> respiratory bronchioles —> alveolar ducts —> alveolar sacs
Which division of the nervous system results in bronchoconstriction? Dilation?
Constriction: parasympathetic
Dilation: sympathetic
What are the two pleural layers? Which one adheres to the thoracic wall?
Visceral envelops the lungs, parietal adheres to thoracic wall.
What type of epithelium is “respiratory epithelium?” Which portion of the airways is covered in respiratory epithelium (conducting vs. respiratory)? Does gas exchange occur?
Pseudostratified ciliated columnar. Covers the conducting portion only. No gas exchange.
Name five cells found in respiratory epithelium.
- Ciliated columnar cells
- Goblet
- Brush cells
- Neuroendocrine (Kulchitsky’s) cells
- Basal reserve cells
What do brush cells do?
Microvilli - might do fluid absorption or chemoreception.
What do basal reserve cells do?
They differentiate into other cell types. Ahhhh! Call in the reserves, man!
What do neuroendocrine (Kulchitsky’s) cells do? Do they stain with H&E?
Contain peptide hormones and catecholamines and are part of the diffuse neuroendocrine system. Not visible with H&E.
Name the three layers of the respiratory epithelium.
- Lamina lucida
- Lamina densa
- Lamina reticularis
What is the lamina reticularis made of? What happens to it in asthma?
Fine fibrillary collagen. It thickens in asthmatics.
What is the most distal component of the conducting portion?
Bronchioles.
What are vibrissae?
Nose hairs.
Where are olfactory mucosa located?
Superior concha, roof/upper third of the nasal septum.
What cells are found in the olfactory mucosa?
Sustenacular (supporting) cells, olfactory nerve cells, and basal cells.
What neuronal type are the olfactory cells?
Bipolar
Where are Bowman’s glands found? What do they do?
Found in the submucosa of nasal cavity. They secrete a fluid over the epithelium in which odorates dissolve, then they bind to olfactory cells.
What two structures are in the larynx?
Epiglottis, vocal apparatus.
What epithelial types are found on the epiglottis?
SSNKE on superior surface, respiratory epithelium on inferior surface.
What two things are found in the lamina propria of the larynx?
Seromucous glands and elastic cartilage plate.
What type of epithelium are found on the false vocal cords and true vocal cords?
False - respiratory epithelium
True - stratified squamous
Describe the composition of the true vocal cords.
Stratified squamous epithelium, with large elastic fiber bundle, the vocal ligament, and a parallel skeletal muscle bundle called the vocalis muscle.
What type of cartilage is found in the larynx?
Mostly hyaline, some elastic.
Describe the histologic layers of the trachea.
Mucosa, submucosa, adventitia.