Respiratory System Flashcards

1
Q

Function of respiration

A

Transport Oxygen into our cells, needed to turn food into energy. Brain will die in 5min in an anoxic or hypoxic environment, then heart dies cause medulla dies
Transport CO2 out of our cells

Respiratory and cardiovascular system work together to distribute oxygen to cells

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2
Q

Function of respiratory system

A

Gas exchange is only in the alveoli of the lungs

Other organs are conduits for passage of air, to purify, humidify and warm the incoming air

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3
Q

Anatomy of respiratory system

A

Upper respiratory tract:
nostril
Nasal cavity
Oral cavity
Pharynx
Larynx

Lower respiratory tract:
Trachea,
Primary bronchus
Lung diaphragm

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4
Q

Nose

A

Nostril leads into the nasal vestibule and then into the nasal cavity

Nasal cavity is lined with mucosa (psuedostratified ciliated columnar epithelium), serves to moisten air, trap and push incoming foreign particles into the spthroat to be stalled, destroy bacteria chemically

3 conchae, house olfactory receptors (superior concha), increases air turbulence
Then meatus, to drain mucus into throat

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5
Q

Snoring

A

Comes from a deviated septum

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6
Q

Sinuses

A

Frontal sinus
Sphenoid sinus
Ethmoid sinuses
Maxillary sinus

Function:
Lighten the skull
Act as resonance chambers for speech
Produce mucus

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7
Q

Palates

A

Separates nasal cavity fro oral cavity

Hard palate is anterior and supported by bone
Soft palate is posterior and unsupported

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8
Q

Why does your nose run in cold weather

A

To warm up the air and keep it moist, it produces extra mucus

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9
Q

Pharynx

A

Muscular, Function:direct air and food into proper passageway

  1. Nasopharynx—superior region behind nasal cavity
  2. Oropharynx—middle region behind mouth
  3. Laryngopharynx—inferior region attached to larynx

Oropharynx and laryngopharynx share common passageway for air and food

Uvula: gives your voice its sound

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10
Q

Tonsils

A

Clusters of lymphatic tissues that protects the body from infections, in pharynx

• Pharyngeal tonsil (adenoid), a single tonsil, is located in the nasopharynx
• Palatine tonsils (2) are located in the oropharynx at the end of the soft palate
• Lingual tonsils (2) are found at the base of the tongue

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11
Q

Larynx

A

Made of 8 hyaline cartilages, thyroid cartilage is the largest, keeps larynx open for air instead of it collapsing
Function: routs air and food into proper channels
Vocalization

Epiglottis, vocal fold and cricoid cartilage

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12
Q

Epiglottis

A

Elastic cartilage

Protects the superior opening of the larynx, the glottis
Directs food to the esophagus and air into trachea

Always open unless swallowing

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13
Q

Vocal fold/cords

A

Vibrate with expelled air (voice)

Glottis: inclues the vocal cords and the opening between them

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14
Q

Trachea

A

Windpipe,

C shaped rings of hyaline cartilage that prevents trachea from collapsing

Lined with Ciliated mucosa which beats in the opposite direction of incoming air. Expels mucus loaded with dust and other debris away from lungs

Inside: lumpen of trachea, mucosa, submucosa, trachealis muscle
Outside: adventitia

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15
Q

Bronchi

A

Have the same physical properties as trachea (cilia, hyalin cratilage, mucus)

Main bronchi enters the lungs at the hilum (root of the lung). Air is warm, moist and free of impurities by the

Right is wider, shorter and straighter than left

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16
Q

Lungs

A

Right lung is a bit bigger than left lung

Right has a middle lobe, left doesn’t (only superior and inferior)

Mid chest between right and left bronchi

In visceral pleura, surrounded by serous fluid, then parietal of pleura membrane, then pleural cavity

Composed of bronchi and bronchioles, alveoli (simple squamous epithelium) and stroma (elastic connective tissue allowing it to expand and recoil)

17
Q

Bronchial respiratory tree

A

Main bronchi
Secondary bronchus
Tertiary bronchus
Bronchiole (smallest, no cartilage)

18
Q

Hillum

A

Pulmonary trunk: caries oxygen poor blood
Splits into:

Pulmonary artery: carries oxygen poor blood
Pulmonary vein: carries oxygen rich blood

19
Q

Respiratory zone

A

Terminal bronchiole lead into respiratory zone, split into respiratory bronchiole, then splitting into alveolar ducts, alveolar sacs and alveoli

Alveoli: only place of gas exchange

Respiratory membrane: air b,old barrier of the alveolar wall and capillary wall

20
Q

Alveoli

A

Thin, alveolar walls composed of simple squamous epithelium

Alveolar pores allows that of an alveoli sac is damaged, air can still flow to the other alveolis or when bronchioles are blocked

Directly attached to pulmonary capillaries

Alveolar capillaries are more numerous and densely arranged than in most other organs, allowing blood to slow down and helping with gas transport through simple diffusion,

One capillary is so thin that only 1 blood cell is allowed to pass, thinness helps with gas exchange

21
Q

Respiratory membrane

A

Apical side facing capillary

Macrophage and surfactant secreting cell (lower adhesion cohesion) present inside alveoli

Through diffusion, gas exchange happens

Macrophage: picks up bacteria, carbon particle and other debris

Surfactant: lipid no,éculé, cuboidal surfactant secreting calls, lowers surface tension to prevent alveoli from collapsing when exhaling

22
Q

4 distinct events of respiration

A

Pulmonary ventilation: air in and out of lungs
External respiration: gas exchange between pulmonary blood and alveoli
Internal respiration: gas exchange between tissue cells and blood in systemic capillaries (capillaries outside of lungs)
Respiratory gas transport: transport of oxygen and co2 via the bloodstream

23
Q

Pressure

A

Pressure increases as volume decreases

Intrapulmonary pressure: pressure inside alveoli

Intrapleural pressure: pressure inside the pleural cavity (should always more negative than the other two pressures, otherwise lungs will collapse)

Atmospheric pressure: pressure of air surrounding your body

24
Q

Pulmonary ventilation

A

Volume changes leads to pressure changes, which leads the flow of gases to equalize pressure

Gas molecules move from high to low pressure

2 phases: inspiration (more volume, less pressure) and expiration (less volume, more pressure)
Diaphragm (skeletal muscle) contracts to give more volume to lungs when inhaling, relaxing then exhaling
Intercostal muscle contracts allows for the ribs to be elevated

Inspiration: active process, diaphragm and intercostal muscle contracts, increase the volume of thoracic cavity, pressure decrease, air flows in
Expiration: depends on natural elasticity (except forced expiration) passive, muscles relax, volume decrease, pressure increases, air flows out

Forced expiration can occur by contraction of intercostal and abdominal muscles, occurs when bronchi,ones are obstructed (asthma, shouting, or pneumonia) not passive

When volume of breath peaks, pressure outside and inside lungs are equal

25
Pleural cavity
Serous fluid in the pleural cavity creates a tight bond between parietal and visceral pleura, allows to expand lungs when your chest expands Must always be more negative than pressure in a,evolution sacs in order to keep air sacs open (acts like a vacuum) Atelectasis: punctured pleural cavity, air enters pleura, cavity, lungs recoil. Other lung works tho. But if infection, then could spread
26
Respiratory capacities
Total volume: 6L. Can never exhale everything, residual volume will stay (1.2L). Surface area is enormous, which leads to the 6L even through it seems a lot Tidal volume: normal quiet breathing , (.5L), when such, less Inspiratoire reserve volume: amount of air tha can be taken forcibly over tidal volume (3.1L) Expiratory reserve volume: amount of air that can be forcibly exhaled after tidal expiration (1.2L) Residual volume: remaining in lung after expiration, cannot be exhaled, allows gas exchange to go on continuously even between breaths and helps keep alveoli open (1.2L) Vital capacity: total amount of exchangeable air (without residual volume) about (4.8L)
27
External respiration
In lungs O2 from alveoli to alveolar capillaries, CO2 opposite
28
Internal respiration
In tissues O2 goes from tissue capillaries to tissue cells, CO2 opposite
29
Carbonic acid buffer system
Transports co2 When co2 gets picked up in your system, it goes to the buffer system, When o2 gets dropped to tissue cells, cells drop co2, causing the system to tilt towards h2co3 Hco3- + h+= h2co3= co2 +h2o
30
Oxygen transport
Oxygen trav,es attached to hemoglobin and forms oxyhemoglobin Small amount dissolved in the plasma
31
Carbon dioxide transport
Transported in the plasma as biocarbonate ion (hco3-) buffer Too much co2 causes accumulation of carbonic acid (h2co3) and decreases blood ph Small amount carried inside red blood cells on hemoglobin but at a different bidding sites than o2
32
control breathing
Medulla: VRG and DRG Pons: pons centers Chemosensors in your brain detect pH changes in cerebrospinal fluid Receptors detect oxygen in aorta Will send afférent information to the medulla and pons using the vagus nerve and glossopharyngeal nerve Will send efferent signal using the phrenic nerves and intercostal nerve to the diagram and intercostal muscles
33
Eupnea
Normal respiration
34
Hyperpnea
Increased respiratory rate
35
Medulla breathing
Ventral respiratory group VRG: sets the rhythm, a pacemaker (neurons that form a pattern of excitation and inhibition without any imput from sensors, excites and inhibits itself) Travels along phrenic nerve and intercostal nerve to excite diaphragm and external intercostal muscles Dorsal respiratory group DRG: sets the timing, receives sensory information and integrates the imput from peripheral stretch and chemoreceptors and communicates this info (ie over inflation) to the VRG. Fine tuner
36
Pons breathing
Pontine respiratory centres tranmit impulses to the VRG fine tunes during certain activities such as vocalisations sleep and exercise Responsible for hyperpneau and eupnia
37
Co2 and h+
Most important factors Lots of co2 means lower pH and high H+ Central chemoreceptors are stimulated by H+ in CSF Peripheral chemoreceptors are stimulated by O2 and H+ in blood. Some in skeletal muscles are stimulated by H+ and lactic acid Carotid body and Aortic body
38
Homeostasis breathing
Physical facts (speaking, exercise, etc) will change respiratory rate. Also emotional (hypothalamus overrides respiratory system) factors and volition pH low, high co2, blood acidosis, will start breathing deeply and rapidly (hyperventilation) pH high, low co2, blood alkalosis, breathing becomes shallow and slow (hypo ventilation) Can cause protein dénaturation
39
Pathway
In arterial blood, if O2 concentration goes down, CO2 goes up, H+ goes up, peripheral chemoreceptors will detects and respond by sending stimulus to respiratory control centers In csf, CO2 increases, H+ increases, central chemoreceptors will detect and respond by sending stimulus to respiratory contro, centers Changes ventilation rate, restoring arterial blood gases