Cardiovascular System Flashcards

1
Q

Cardiovascular function

A

Transportation of molecules using blood

Deliver oxygen and nutrients, remove co2, ammonia and other metabolic waste

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2
Q

Heart location

A

Pericardial, in the mediastinum

Apex: points towards the left hip and rests on diaphragm (5th intercostal space) (point of maximal intensity PMI is where we put stethoscope)

Base points towards right shoulder, behind second rib

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3
Q

Pericardium

A

Serous membrane covering the heart
Serous fluid
Provides a friction free environment
Protects and anchors the heart to structures like the diaphragm

Superficial to internal:
Fibrous pericardium
Parietal layer of serous pericardium
Pericardial cavity filled with serous fluid
Visceral layer of serous pericardium

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4
Q

Heart anatomy wall

A

Heart wall composed of 3 layers

Sup to int:
Epicardium ( visceral serous layer too)
Myocardium (cardiac muscle, responsible for contraction)
Endocardium (insures blood gluides in the chamber, no friction) simple squamous epithelium (endothelium)

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5
Q

Ventricles

A

Left ventricle thicker because it pumps blood to the whole body

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6
Q

Blood circulation

A

Heart acts as two pumps:

Pulmonary circuit pump (right side of heart to lungs)

Systemic circuit pump (left side of Herat to the rest of the body)

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7
Q

Systemic circuit

A

Superior/inferior vena cava
Right atrium
Right Ventricle
pulmonary trunk
Will go either to left or right pulmonary artery (left and right lung)

Pulmonary vein
Left atrium
Left ventricle
Aorta

Blood flows simultaneously everywhere

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8
Q

Four chambers of the heart

A

Atria:
Receive blood form veins
Fill the ventricles
Blood enters passively under low pressure
Contract together

Ventricles:
Thick walled
Blood is propelled into arteries
Contact together

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9
Q

Blood vessels

A

Arteries carry blood away heart
Veins carry blood toward heart

Superior vena cava: lower body to right atrium
Inferior vena cava: lower body to right atrium
Pulmonary veins: lungs to atrium (oxygen rich blood)

Pulmonary trunk: right ventricle to lungs via pulmonary arteries (oxygen poor)
Aorta: left ventricle go body, in aorta ascending arteries are:
Brachioceohalic trunk: right arm
Left subclavian artery: left arm
Left common carotid artery: goes straight to head

Arteries pump blood, veins don’t

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10
Q

Cardiac circulation

A

Enters directly off the aorta
Cardiac arteries:bring oxygenated blood to the heart:
Right coronary artery
Marginal artery
Circumflex artery
Left coronary artery

Cardiac veins:
Great cardiac vein: “
Small cardiac vein: drain the myocardium of blood
Anterior cardiac vein: “
Coronary sinus: on posterior, receives blood from cardiac vein, then empties to right atrium

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11
Q

4 heart valve

A

Right atrioventricular vale (tricuspid) (chordate tendineae)

Left atrioventricular vale (bicuspid, mitral) (papillary muscle)

Pulmonary semilunar valve

Aortic semilunar valve

Has cusps, made of thin tough membrane
Open and close due to pressure change

Sound heard is the valves closing

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12
Q

AV valve

A

Between atria and ventricle

Open during heart relaxation, closed during ventricular contaraction

Anchored the cusp I place with the chordate rendineae tot eh papillary muscle

Operation:
Blood returning to the atria puts pressure on AV and go into ventricle passively
As ventricle fills, AV cusp hand limply into the ventricle
Atria contracts to eject blood in the into the ventricle, pressure increases in atria, AV still open
Ventricle contracts, pressur increases in ventricle, forcing blood against cusps, AV close

Tricuspid and bicuspid close at the same time, making lub sound

Majority of time spend open

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13
Q

Semilunar valve

A

Between ventricle and artery

Closed during heart relaxation, open during ventricular contraction

Operation:
Pressure in ventricules are so high that blood is pushed against valve, forcing semilunar valves open
Blood gets ejected into aorta/pulmonary trunk
Ventricles relax, pressure falls, blood falls back onto cusps of semilunar valve, forcing them to close

Semilunar valves close simultaneously, making dup sound

Majority of time closed

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14
Q

Congestive heart failure

A

Imbalance of pumping action between two sides of the heart
Eventually whole heart fails

Right heart fails, peripheral congestion, edema (swelling)

Left heart fails, pulmonary congestion, fluid accumulates in lungs and person drowns

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15
Q

How does the heart beat

A

Cardiac muscle contracts independently of nerve impulses (intrinsic conduction system)
Ensures all 4 chambers of the heart contracts in a regular continuous and unified rhythm

Atria cells beat a bit faster than ventricular cells,

through intercalated disc, the intrinsic conduction passes to the non pacemakers cells

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16
Q

Intrinsic conduction system

A

4 special nervous tissue: (not nervous system)
Sinoatrial node: in right atrium, hearts pacemaker, sends electrical signal to both atrium and to AV node
Atrioventricular node: at the junction of atria and ventricles, ensures both ventricules contract together
Atrioventricular bundle (bundle of his) and bundle branches are in interventricular septum
Purkinje fibers: spread sighing the ventricle wall muscles

17
Q

Intrinsic conduction path

A

SA node
Atrial muscle
AV node (delay for atria to relax) atria contract
Purkinje fibers
Ventricular muscle
Ventricles contract

18
Q

Heart physiology

A

In addition to the intrinsic conduction system, the nervous system also regulates heart activity, nerves of the autonomic nervous system act like brakes or accelerators to increase or decrease heart rate (medulla oblungata)

19
Q

Cardiac cycle

A

One complete heartbeat

Systole (contraction, high pressure)
Diastole (relaxation, low pressure)

Atrial diastole
Atrial systole
Isovokumentric contraction
Ventricular systole
Isovokumetric relaxation

20
Q

Atrial diastole

A

Heart is relaxed
Pressure in heart is low
AV valve open
Blood flows passively into atria and ventricles
Semilunar valves closed

21
Q

Atrial systole

A

Just before, SA node have been activated
Ventricles stay in diastole
Atria systole
Blood forced into ventricles

22
Q

Isovolumetric contraction

A

Atrial systole ends (high pressure in atria)
Ventricular systole begins
Intraventricular pressure rises
AV valve close (lub)
For a moment, ventricles are completely closed

23
Q

Ventricular systole

A

Ejection phase
Ventricles systole
Intraventricular pressure now surpasses the pressure in the major arteries (pulmonary trunk and aorta)
Semilunar valve open
Atria is relaxed and filling with blood, back into diastole
Blood pressure is a measure of of pressure in this phase

24
Q

Isovolumetric relaxation

A

Ventricular diastole begins
Pressure falls below that of major arteries
Semi,Unser valve close (dup)
For a moment, ventricules completely closed
When atrial pressure increases above Intraventricular pressure, AV valve open

25
Electrocardiogram
ECG SA node: PR interval, electrical signal going to atria, contract AV node: QRS duration, electrical signal going to ventricles, contract T: ventricular repolarization Normal heartbeat Trachycardia (elevated) Slow heartbeat (bradycardia)
26
Cardiac output
Amount of blood ejected from ventricles in one minute, about equal for left and right ventricle CO= stroke volume (volume per cardiac cycle) x heart rate
27
Regulation stroke volume
Starlings law: how far heart ventricules stretches during diastole is directly related to how much blood is ejected (stronger contraction), Increased stroke volume Veins are surrounded by skeletal muscles. As walking/running, skeletal muscle will squeeze veins and return blood towards heart (valves are present to insure blood only travels one way) Increased stroke volume means heart beat can slow down, heart works less
28
Sympathie nervous system control of Herat
Nerves stimulate SA and AV node and cardiac muscle to increase heart rate, more o2 and glucose to cells Heart stimulated by sympathetic cardioaccelerator center, which sends impulse to SA and AV node and ventricular myocardium, to depolarize them, increases probability of firing impulse Effect on myocardium is increase contractility thus increasing force and volume of contraction
29
Parasympathetic nervous system control of heart
Right vagus nerve acts on SA node to slow and steady the heart The heart is inhibited by the parasympathetic cardioinhibitory center,sends impulse brought vagus nerve to the SA and AV node and the atrial myocardium, releases acytocholine, hyperpolarization, reduces chances of firing impulse
30
Neural regulation of the heart rate
Medulla contains nuclei called cardiac control center Baroreceptors (stretch) found in carotid sinus and the aorta and send it to the medulla Sympathetic (excitatory) and parasympathetic (inhibitory) send motor nerve impulses to the heart Also regulated by chemoreceptors that respond to change in o2, co2 and h+ and hormones Hypothalamus also can override and regulate heart rate, increase rate of depolarization in nodes and contractioty of the cardiac muscle
31
Normal vagal tone
Heart at rest
32
Vagusstoff
Otto loewi discovered acytolcholine has impact of heart, named substance vagusstoff (acetylcholine) Epinephrine and T3/T4 will increase heart rate also
33
Cardiac reserve
heart's ability to quickly adjust to immediate demands placed upon it the maximum % that the cardiac output can increase above normal