Respiratory System Flashcards
Upper respiratory system
Nose and pharynx (throat)
Lower respiratory system
Larynx(voice box), trachea(windpipe), bronchial tubes, and lungs
External nose
Consists of bone and cartilage covered with skin and lined by mucous membrane
Region just inside nostrils
Nasal vestibule lined with coarse hairs
Floor of the internal nose
Hard palate
Which forms the posterior portion of the roof of the mouth, is an arch-shaped muscular partition between the nasopharynx and oropharynx that is lined by mucous membrane
Soft palate
Two openings in internal nose to pharynx
choanae
Inside of the external and internal nose divided into left and right sides by
nasal septum, formed by vomer
Type of cell lining nasal cavity
Pseudostratified columnar epithelium with goblet cells
Functions of the nose
Warming, filtering, and moistening incoming air
Picking up olfactory stimuli (detecting odors)
Providing a resonating chamber for phonation
Pharynx
Upper airway, 5 inch tube that extends from the choanae down to the junction of the larynx and esophagus
Function of pharynx
Lined with mucous membrane
Serves as passageway for air and food
Functions as resonating chamber
Three divisions of pharynx
Nasopharynx
Oropharynx
Laryngopharyx
Nasopharynx
Behind nose, four openings in wall(two from choanae, two from auditory tubes)
Lined with ciliated pseudostratified columnar epitheium
Oropharynx
Behind mouth, one opening into it, the FAUCES from the mouth, contains palatine and lingual tonsils, functions BOTH as respiratory and digestive pathway
Lined with nonkeratinzed stratified squamous epithelium
Laryngopharyx
Behind larynx, BOTH respiratory and digestive pathway
Lined with nonkeratinized stratified squamous epithelium
Larynx
Connects pharynx with trachea
Lining of superior larynx to vocal fords
Nonkeratinzed stratified squamous epithelium
Lining of larynx inferior vocal folds
Ciliated pseudostratified columnar epithelium
Thyroid cartilage (Adam’s apple)
Cartilage of larynx, single large triangular piece of cartilage that forms the anterior wall
Epiglottis
Single leaf shaped piece of cartilage that sits on TOP of larynx, during swallowing it closes of rima glottidis(space between the vocal folds)
Cricoid cartilage
In larynx, single inferior piece of cartilage attached to trachea, used as landmark for tracheotomy
Two folds formed by mucous membrane of the larynx
Superior ventricular folds and vocal folds
False vocal dords
Ventricular folds
True vocal cords
Vocal folds
Laryngitis
Inflammation of the larynx
Vocal folds make higher pitched sound when
When pulled taut by various muscles and cartilages
Trachea
Tubular passageway about 5 inches in length and one inch in diameter
Anterior to the esophagus and extends from larynx to T5 where it divides into right and left main bronchi
Lining of trachea
Lined with ciliated pseudostratified columnar epithelium and wall consists of smooth muscle, elastic connective tissue
How many rings of cartilage in trachea?
16 to 20
Connection by trachea to esophagus along c shaped rings
Trachealis muscle
Carina
Where the trachea divides into left and right main bronchi, internal ridge
One of the most sensitive areas to trigger a cough reflex
Widening and distortion of carina
Indicates carcinoma of the lymph nodes around region where trachea divides
Two methods to reestablish airflow if there is obstruction in trachea
Tracheotomy and endotracheal intubation
Tracheotomy
Longitudinal incision made into trachea below the cricoids cartilage
Divisions of respiratory passages from trachea
Lung (Main bronchus)
Lobes (Lobar bronchus)
Bronchopulmonary segments (Segmental or tertiary bronchi)
Bronchioles
Lobules (Terminal bronchioles)
Alveolar ducts
Alveolar saccules
Pulmonary alveoli (air sacs)
Three MICROscopic respiratory passageways
Alveolar ducts, alveolar saccules, Pulmonary alveoli
The continuous branching from the main bronchi through the terminal bronchioles forms an extensive tree called
Bronchial tree
X ray of bronchial tree
Bronchogram
Serous membrane covering lung
Pleura
Lining of chest wall
Parietal layer
Layer covering the lung
Visceral layer
Space between the parietal layer and visceral layer
Pleural cavity
Inflammation of the pleural
Pleurisy (pleuritis) Rubbing of two layers together
Narrow superior part of lung
Apex
Broad inferior portion of lung
Base
Surface of lung that faces the heart
Mediastinal (medial) surface
On meastinal (medial surface), region through which bronchi, blood vessels, lymphatics, and nerves pass through
Hilum
Structures that pass through the hilum and are wrapped in connective tissue
root of the lung
Left lung medial concavity where the heart lies
Cardiac notch
External surface of lung is divided into lobes by
Fissures (slits)
Both lungs are divided by a
Oblique fissure
What lung has an additional horizontal fissure
Right lung
What is each lobe supplied by
lobar bronchus
The lungs contain how many pulmonary alveoli
300 million
70 meters
Walls of pulmonary alveolus contain what three cells
Pneumocyte type I cell
Pneumocyte type II cell
Alveolar macrophage
Pneumocyte type I cell
Simple squamous epithelial cell, make up 95% of pulmonary alveolar wall, main site of gas exchange
Pneumocyte type II cell
Rounded or cuboidal cells found between pneumocyte type I cells, secrete surfactant which prevents pulmonary alveoli from collapsing
Alveolar macrophages
remove fine dust particles and other debris from the pulmonary alveoli
The exchange of oxygen and CO2 occurs by diffusion through a membrane formed by the pneumocyte type I cells of the wall of a pulmonary alveolus and the surrounding wall of a blood capillary form what
Respiratory membrane
Pulmonary embolism
blood clot in the pulmonary arterial system that can result in lung dysfunction and death
Main bronchus supplies the
entire lung
Lobar bronchus supplies
lobe of the lung
Segmental bronchus supplies a
Bronchopulomary segment
Terminal bronchiole supplies a
Lobule of a lung, last of the macroscopic tubes
Alveolar ducts(micro) supply
pulomanary alveoli
Average rate of respiration
14-18
Respiration is defined as
one inhalation followed by one exhalation
Minute ventilation (MV)
Total volume of air inhaled and exhaled per minute calculated by multiplying respiratory rate by tidal volume
Average 6 liter/minute
Pulmonary ventilation
process by which respiratory gases are exchanged between atmosphere and lungs (Inhalation and exhalation)
Partial pressures
Eupnea
Normal quiet breathing
Two types of eupnea
Costal and diaphragmatic
Costal breathing (chest or shallow)
Primary muscles involved are the external intercostals
Diaphragmatic breathing (abdominal or deep)
Primary muscle used is diaphragm
Atelectasis
collapsed lung or portion of lung
Factor that prevents collapse of pulmonary alveoli
Surfactant
Deficiency of surfactant in an infant
Infant respiratory distress syndrome (RDS)
Apparatus to measure respirations
Respirometer
Record of respirations
Spirogram
Amount of air moved during normal quiet breathing
500mL
How much air remains in nose, mouth, pharynx, larynx, trachea, bronchial tubes
150mL
Anatomic dead space
Volume of air that does not participate in gaseous exchange
Inspiratory reserve volume
3000mL
Volume of air that can be forcibly inhaled above tidal volume
Expiratory reserve volume
1200 mL
Volume of air that be forcibly exhaled over and above tidal volume
Residual volume
1200mL
Volume of air remaining in lungs after forcible exhalation
Minimal volume
Volume left after chest cavity is opened
Serves as medical and legal tool to determine if an infant was still born or took one breath
Minimal volume
Capacity
Adding together various volumes
Inspiratory capacity
Sum of tidal volume and inspiratory reserve capacity
3600mL
Functional residual capacity
sum of residual volume and expiratory reserve volume
2400mL
Vital capacity
Sum of inspiratory reserve volume, tidal volume, and expiratory reserve volume
4800mL
Total lung capacity
sum of all volumes
Charles’ Law
volume of gas is directly related to temperature
Temperature increases, volume _______
Increases
Dalton’s Law
each gas in a mixture of gases exerts its own pressure called partial pressure and behaves as if no other gases are present
Percentage of N in air
78.6%
Percentage of O2 in air
21%
Percentage of CO2 in air
0.04%
Nitrogen narcosis
Excessive amounts of nitrogen with symptoms similar to ETOH intox
“Rapture of the deep”
Decompression sickness
Diver surfacing too quickly casing nitrogen to form gas bubbles in tissue
Joint pain in limbs, paralysis, unconsciousness
External respiration
exchange of respiratory gases, by diffusion, between the pulmonary blood through the respiratory membrane
Deoxygenated blood to oxygenated blood
Why does external respiration occur?
Because of the differences in between partial pressures
PP of pulmonary alveolar air P02 and P02 of deoxygenated blood
105mmHg and 40mmHg
PCO2 of pulmonary deoxygenated blood and pulmonary aleveolar air
45mmHg and 40 mmHg
Thickness of respiratory membrane
0.5 micrometers
mL of blood in lungs at rest
900mL
Pulmonary disorders
any disease that decreases the functional surface area of the respiratory membrane
Ex. Emphysema and pneumonia
Internal respiration
Exchange of respiratory gases between systemic blood and tissue cells
Also conversion of oxygenated blood into deoxygenated blood
P02 of systemic oxygenated blood and tissue cells
105 and 40
PCO2 of tissue cells and systemic oxygenated blood
45 and 40
Abdominal thrust maneuver
First aid procedure designed to clear the airway of obstructing objects
Asphyxia
Oxygen starvation due to low atmospheric oxygen or interference with ventilation, external respiration, internal respiration
Aspiration
Inhalation of a foreign substance such as water, food, or foreign body into bronchial tree
Black lung disease
A condition where lungs appear black instead of pink due to inhalation of coal dust over a period of many years
Bronchiectasis
A chronic dilation of the bronchi or bronchioles resulting from damage to bronchial wall, ex resp. infections
Bronchoscopy
Visual examination of the bronchi through a bronchoscope
Cheyne-stokes respirations
Repeated cycle of irregular breathing that begins with shallow breaths that increase in depth and rapidity and then decrease and cease altogether for 15 to 20 seconds
Normal in infants
Seen before death in pulmonary cerebral cardiac and kidney disease
Dyspnea
Painful or labored breathing
Epistaxis
Nose bleed
Hypoventilation
Slow and shallow breathing
Respiratory failure
Respiratory system cannot supply efficient O2 to maintain metabolism or cannot eliminate enough CO2 to prevent respiratory acidosis
Rhinitis
Chronic or acute inflammation of the mucous membrane of the nose due to viruses, bacteria or irritants. Excessive mucus production produces runny nose, nasal congestion, postnasal drip
Sleep apnea
Person repeatedly stops breathing for 10 seconds or more while sleeping, occurs because loss of muscle tone in pharyngeal muscles allow airway to collapse
Sputum
Mucus and other fluids from air passages that is expectorated(expelled by coughing)
Strep throat
Inflammation of the pharynx caused by bacterium Streptococcus pyogenes, may involve tonsils and middle ear
Tachypnea
Rapid breathing rate
Wheeze
A whistling, squeaking, or musical high pitched sound during breathing from a partially obstructed airway
How many more times does CO bind to hemoglobin
200x
Three ways 20 ml of O2 is carried
0.3 mL Blood plasma
19.7 mL combined with hemoglobin
Reduced hemoglobin + O2 yields oxyhemoglobin
How many mL of CO2 in 10 mL of deoxygenated blood
4 mL
Percentages of CO2 in in deoxygenated blood
7% blood plasma
23% hemoglobin carbaminohemoglobin
70% bicarbonate ions breaking down into H+ and HCO3-
Hypoventilation leads to
Acidosis
2 items make up the respiratory center
Medullary Respiratory Center (MRC)
Pontine Respiratory Group (PRG)
What makes up Medullary Respiratory Center (MRC)
Dorsal respiratory group (DRG) and Ventral respiratory group (VRG)
Conscious breathing occurs because of the
Cerebral cortex
Baroreceptors
Neurons in the walls of the bronchi and bronchioles that become activated by stretching
Inflation reflex (Hering-Brueaur)
When lungs are overinflated the baroreceptors send nerve impulses to the DRG that inhibit the DRG. As a result, the diaphragm and external intercostal muscles relax and exhalation occurs. In response the baroreceptors are no longer stimulated, the DRG is no longer inhibited, and a new inhalation begins
Reflex prevents excess inflation of the lungs
In the medulla, groups of receptor neurons that are responsive to changes in CO2(H+) and O2 levels
Central chemosenstive area and peripheral chemoreceptors
Normal blood PC02
40mmHg
PCO2 above 40mmHg
Hypercapnia
Pontine Respiratory Group (PRG)
Sends impulses to modify breathing to Dorsal Respiratory Group (DRG)
Ventral Respiratory Group (VRG)
Sets basic rhythm of breathing and controls forceful breathing to Dorsal Respiratory Group (DRG)
Dorsal Respiratory Group (DRG)
Sends impulses to diaphragm and external intercostal muscles contract to allow normal quiet breathing