Respiratory Physiology - Gas and Transport Flashcards
What is the sea level partial pressures for O2, CO2 and N2?
PN2 = 593mmHg PO2 = 160mmHg PCO2 = 0.2mmHg
What is the partial pressure of O2 in a normal airway?
inspiration = 149mmHg expiration = 100mmHg
What is the partial pressure of CO2 in a normal airway?
Inspiration = 0mmHg Expiration = 40mmHg
What is the partial pressure of O2 the alveoli?
100mmHg
What is the partial pressure of CO2 the alveoli?
40mmHg
What is the partial pressure of O2 and CO2 at the arterial level?
O2 = 100mmHg CO2 = 40mmHg
What is the partial pressure of O2 and CO2 at the mixed venous level?
O2 = 40mmHg CO2 = 46mmHg
What are the 2 methods of transport for oxygen in the blood? What’s the percentages of each?
- physically dissolved = 1.5%
2. Bound to hemaglobin = 98.5%
What are the 3 methods of transport for CO2in the blood? What’s the percentages of each?
- Physically Dissolved = 10%
- Bound to Hb = 30%
- As Bicarbonate
What are the 4 ways an oxy-Hb curve will shift to the right (reduce affinity)?
- Increased PCO2 in tissues
- Increased Acid
- Increased Temp.
- Increased 2,3,biphosphoglycerate
The binding of H+ and CO2 to Hb reduces Hb-O2 affinity and increases O2 unloading via what effect?
The bohr effect
What chemical is produced by RBCs when Hb-O2 is chronically low and causes unloading of O2 at a given pH?
2,3, biphosphoglycerate
Term: Having low arterial blood oxygen
Hypoxic Hypoxia
What 2 things cause hypoxic hypoxia?
- inadequate gas exchange by normal or reduced PO2
2. Blocked airway, COPD, exposure to high altitudes
Term: Reduced O2 carrying capacity of the blood, lungs are functioning normally.
Anemic Hypoxia
