Respiratory: Physiology and Pharmacology

Question 1

Which type of lung cancer can cause hyponatremia?

Answer 1

Small cell lung cancer can cause syndrome of inappropriate ADH secretion which results in a euvolaemic hyponatremia

Question 2

Describe the mechanism of action of theophylline

Answer 2

A methylxanthine drug with bronchodilator and anti-inflammatory action. Has many side effects and drug interactions.

Question 3

Describe the mechanism of action of fexofenadine

Answer 3

A competitive H1 receptor antagonist used to treat allergic rhinitis.

Question 4

Describe the mechanism of action of ipratropium bromide

Answer 4

A short acting drug that blocks acetylcholine receptors non-selectively. Can be delivered intranasally to treat rhinorrhoea.

Question 5

What is the mechanism of tiotropium?

Answer 5

Anti choliergic drug which is selective for M3 receptors and as a long half life

Question 6

What is the mechaism of montelukast?

Answer 6

A cysteinyl leukotriene receptor antagonist used to treat asthma and allergice rhinitis.