Respiratory Physiology Flashcards
What is the role of the lungs?
- To bring in fresh air, rich in the O2 needed to fuel the body
- To expel the waste gas (CO2) produced from cells in the body.
Why do we breathe?
To maintain blood, gas homeostasis (O2, CO2 and pH)
What is partial pressure?
Sum of the partial pressures (mmHg) or tensions (torr) of a gas must be equal to total pressure.
How can partial pressure of gas be calculated?
Pgas = fraction of a gas in gas mixture(Fgas) X barometric pressure
Pgas=Fgas X Pb
What happens in airwyas to air?
Air warmed and humidified (becomes saturated with water vapour)
What is the barometric pressure at sea level?
760mmHg
What are the respiratory muscles?
- Diaphragm major; inspiratory, dome-shaped skeletal muscle
- Other respiratory skeletal muscles activate during more strenous breathing.
What is the mechanisms by which quiet breathing occurs?
- Inspiration = active
- Diaphragm contracts downwards pushing abdominal contents outwards.
- External intercostals pull ribs outwards and upwards
- Expiration = Passive
- Elastic recoil
What are the mechanisms of strenous breathing?
- Inspiration = active
- Greater contraction of diaphragm and external intercostals.
- Inspiratory accessory muscles active eg. sternocleid omastoid, alae nasi, gengiglossus
- Expiration = Active
- Abdominal muscles (rectusabdominus, internal oblique, external oblique and transversus abdominus.
What are the components of the resp. system?
- Nasal cavities, paranasal sinuses (filter, warm, air)
- Pharynx, larynx
- Bronchi
- Alveoli
- Trachea
- Lungs
Where and how does filtering of air happen?
- Upper airways to bronchioles lined by pseudo stratified, ciliated, columnar epithelium.
- Inhaled particles stick to mucous. Mucous moved towards mouth by beating cilia.
Why do we have a cough refulx?
Protective reflux - rids airways of offending material
What are RAR’S?
Rapidly adapting pulmonary stretch receptors are found in epithelium of resp. tract.
What is the role of RAR’s?
Activated by dust, smoke, ammonia, oedema etc.
RAR’s afferents of vagus nerve, which send signal to brain.
What is the process of the cough reflux?
- Stimulation of RAR’s by irritant
- Afferent info sent via vagus nerve, which send signal to brain
- Brain sends info to diaphragm and external intercostals to induce strong contraction
- Air rushes into lungs
- Abdominal muscles contract to induce expiration
- Glottis opens to forcefully release air and irritants