Respiratory Physiology 1 Flashcards

1
Q

What is positive pressure breathing?

A

Creating positive pressure in relation to the lungs, forcing air into the lungs

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2
Q

What is negative pressure breathing?

A

Decreasing pressure relative to atmosphere, causing gradient, causing air to be drawn in

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3
Q

Pip

A

Intrapleural pressure aka intrathoracic pressure

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4
Q

Palv

A

Alveolar pressure

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5
Q

Ptp

A

Transpulmonary pressure (Palv-Pip)

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6
Q

Patm

A

Atmospheric pressure

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7
Q

Steps of inspiration

A

1) Ribcage up and out
2) Diaphragm go flat - contract
3) Parietal membrane pull out, visceral pleural pulled out too
4) Pip decreases as volume increases
5) Increases difference between Palv and Pip which increases Ptp
6) Bigger the Ptp the greater the enlargement of the alveoli
7) Alveolar volume increases
8) Palv decreases
9) Change in pressure between atmosphere and alveoli, air drawn in to increase pressure

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8
Q

Steps of expiration

A

1) Relaxation of inspiratory muscles, chest wall decrease, and recoil back in
2) Space between pleural decreases
3) Difference between Pip and Palv decreases
4) Ptp decreases
5) Alveolar wall recoils, alveolar volume decreases
6) Palv increases
7) Change in pressure between atmospheric and alveolar
8) Force air out of lungs
9) Lung tissue recoilnd help alveoli go to normal size

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9
Q

What is pneumothorax?

A

Air leaks into the space between the lung and chest wall
The air pushes on outside of the lung and causes it to collapse/partially collapse
Now natural tendency of lung to collapse- elastic recoil of alveoli

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10
Q

What is resistance?

A

Resistance of respiratory tract to airflow during inspiration and expiration

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11
Q

What is compliance?

A

Ability of lungs to stretch and expand

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12
Q

Why are children at greater risk of an obstructive disease?

A

1) Smaller airways

2) Higher resting respiratory rates

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13
Q

What is an obstructive disease?

A

Increased resistance by a narrower airway

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14
Q

What is a restrictive disease?

A

Decreased compliance, decreased ability of lungs to expand

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15
Q

What is fibrosis?

A

Thickened stiff tissue which makes it more difficult for lungs to work properly

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16
Q

What is emphysema?

A

Large air spaces are not cleared of air on exhalation (air pockets called bullae) due to the destruction of alveolar walls
These bullae do not exchange oxygen and carbon dioxide like normal lung tissue

17
Q

Where is surfactant released from?

A

Type 2 alveolar cells

18
Q

What does surfactant do?

A

Lowers surface tension- less likely for alveoli to get together- increases compliance and improves work of breathing

19
Q

What is the perfusion distribution in the lung?

A

Perfusion pressure falls above level of heart and increases below it
Blood flow increases from apex to base

20
Q

What is the ventilation distribution in the lung?

A

Greater ventilation at the bottom of the lung

21
Q

What can lead to a decrease in ventilation in lungs?

A

Breathing in foreign body

22
Q

What can lead to a decrease in perfusion in lungs?

A

Clot formation- pulmonary embolism

Block blood flow to that particular area of lung.