Respiratory Module 4 Flashcards

1
Q

Two mechanisms of pulmonary edema

A
  1. High pressure edema: CHF, volume overload
  2. Increased permeability edema: any disease process that damages the capsular endothelium or alveolar epithelium - increases vascular permeability within the lungs
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2
Q

Management of cardiogenic pulmonary edema

A
  1. Frusemide 2-3mg/kg IV or IM
    - pink froth: 4-6mg/kg
    -repeat q30mins - 10-30mins to see effects
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3
Q

How does frusemide work to reduce PE

A

Clears PE by reducing blood volume and reduction in pulmonary capillary pressure
- works directly by affecting pulmonary vascular effects and bronchodilatory effects

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4
Q

What are 4 non-invasive ways of delivering oxygen therapy?

A
  1. Oxygen tents
  2. Oxygen mask - FiO2 35% if loose, 50-60% if tight, tightfitting
  3. Flow by - 25-40%
  4. CPAP (continuous positive airway pressure) - need heavy sedation required, poorly tolerated
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5
Q

What are 5 invasive ways of delivery oxygen therapy?

A
  1. Intubation
  2. Transtracheal O2 40-60%
  3. Nasal prong/High flow O2 25-50%
  4. Nasal catheters 40-70% - jet lesions
  5. Naso-pharyngeal catheter - BOAS (deeper in phayrnx
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6
Q

How to preform a thoracocentesis?

A
  1. O2 therapy flow by
  2. Clip both sides of chest and sterile prep
  3. Mild sedation: Butorphanol/Midaz + ketamine
  4. Ideally 3 people, to hold, to hold needle and one
    for syringe
  5. Location: 8/9th rib intercostal space (ventral 1/3 fluid, dorsal 1/3 air)
  6. Lidocaine LA - 1mg/kg both sides cats/dogs
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7
Q

What are the chest drain techniques?

A
  1. Seldinger
    • Over the wire
    • Narrow bore drains
    • GA or sedation
    • Better tolerated
    • Less traumatic
    • Can be used for pyothorax
  2. Trochar Drain
    • GA only
    • Must be tunnelled
  3. Forceps insertion
    • GA only
    • Must be tunnelled
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8
Q

How to place a seldinger chest drain?

A
  1. Measure from tip of axilla (2nd rib) to 8th/9th
    intercostal space
  2. Infiltrate LA
  3. Measure a releasing incision with number 11
    blade
  4. Advance a large catheter (14g) perpendicular in to
    the chest
  5. Turn catheter toward ipsilateral elbow and
    remove stylet - thumb over the top
  6. Slide in the guide wire to the marked amount
    (hold on to the whole time)
  7. Remove catheter over the wire
  8. Slide on the drain, twisting motions, remove
    guide-wire and place thumb over the top
  9. Thumb over the end after removal of the guide
    wire or clamp
  10. Sutures through wings of butterfly and then
    neck of drain
  11. Orthogonal views of x-rays
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9
Q

What are options for relieving a complete obstruction?

A
  1. Needle Tracheostomy
    - Clip a patch over ventral neck
    - Large bore needle inserted between tracheal
    rings - IV catheter
    - Cricothyroid ligamnet - easier to palpate, distal to
    adams apple
    - Attach O2
  2. Surgical Tracheostomy
    - 2-5cm midline incision extending caudally from
    cricoid cartilage
    - Use retractors to see field, dont dissect lateral to
    tracheal as recurrently laryngeal nerve is there
    - Identify the midline raphe between the
    sternohyoid muscles (white line)
    - Blunt dissection through raphe then dissect
    muscle bellies to trachea
    - Loop sutures through 3-4 or 4-5th ring and label
    up/down
    - Incise through annular liagment - NEVER more
    than 50% circumference
    - Place in tracheostomy tube
    - Connect to O to and get tape one
    - Close skin around incision
    - Heat and moisture exchanger
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10
Q

What are causes of non-cardiogenic pulmonary edema?

A

Broad category of increased permeability edema - inflammatory diseases

  • Neurogenic PE: seizures, head trauma,
    electrocution
  • Negative PE: dry drowning,
    strangulation, sudden/sharp tug on lead
  • Aspiration pneumonitis/pneumonia
  • Vaculitis
  • ARDs
  • Pneumonia
  • Re-expansion PE
  • Drowning Injury
  • PTE
  • Smoke inhalation
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11
Q

What are predisposing factors to aspiration?

A
  • LP
  • Megaoesophagus
  • V+
  • Regurgitation
  • Sedation/GA
  • Delayed gastric emptying
  • Gastric intubation
  • Seizures
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12
Q

What causes aspiration pneumonitis?

A

This is inflammation of the lung secondary to inhaling a chemical irritant - may or may not progress to pneumonia
- persists up to 48hrs, vascular permeability occurs 1-2 hours after incident

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13
Q

Treatment of aspiration pnuemonitis?

A
  1. Oxygen
  2. Nebulisation
  3. Light exercise - to promote expectorisation
  4. Mucolytic - n-acetyl

If progresses to pneumonia
- E.coli most common - 20mg/kg IV q8hrs
- Doxy if puppies

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14
Q

What causes ARDs and how is it diagnosed clinically?

A

ARDs is a syndrome that is usually a life threatening complication of critical illness - massive inflammatory process leading to alveolar damage characterised by protein rich inflammatory edema within the alveoli followed by fibrotic changes
- pulmonary or extra-pulmonary causes

Diagnostic criteria
1. Acute onset dyspnoea <72hrs
2. Pre-existing severe acute clinical illness
3. Bilateral pulmonary infiltrates
4. Severe hypoxaemia on room air or PaO2
<45mmHg, SPO2 <85%, A-a gradient >50
5. No heart disease

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15
Q

What are causes of PTE?

A
  • Immune mediated disease
  • Sepsis
  • Trauma
  • Neoplasia
  • Pancreatitis
  • Surgery
  • DIC
  • Endocarditis
  • Myocardial diseases
  • FIP
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16
Q

How to choose clot preventative agents?

A

PTE
- Venous embolis: composed of predominantly
clotting factors
- Anticoags > Antiplatelets
- LMWH, rivaroxaban, anti-Xa agent

ATE
- Arterial embolis: composed of platelets
- Antiplatelet > Anticoags
- clopidogrel

When PTE dissolves can cause a shower of smaller emboli that can cause microscopic PTE

17
Q

How does smoke inhalation cause injury?

A
  1. Direct thermal injury
  2. Super heated matter carried further down tree
  3. Irritant gasses (amonia, HLC, benzene)
  4. Carbon monoxide toxicity
  5. Cyanide toxicity - from burning plastics/nylon
  6. Smole inhalation: inactivation of surfactant =
    shear injury/atelectasis
  7. alveolar haemorrhage = obstruction from bleeding
18
Q

Treatment of smoke inhalation?

A
  1. Oxygen - 100% O2 therapy via intubation
    • Will quickly reverse carboxyhb by out competing
      the CO for Hb receptors
      - On room air will take 3.5-6hrs but on 100% O2
      would take 80-90mins
  2. Mechanical ventilation
  3. Terbutaline (0.01mg/kg IV, IM) - especially if
    wheeze
  4. N-acetylcystein to scavenge for free radicals and even can be mucolytic
  5. Abs if indicated by BAL
  6. Judicious fluids
19
Q

Causes of pulmonary haemorrhage?

A
  • Pulmonary contusions
  • Secondary to trauma
  • Coagulopathy
  • Thrombocytopenia
  • Pulmonary inflammation
  • Neoplasia
  • Thromboembolism
  • Lepto/Lungworm
  • CHF
20
Q

Management of pulmonary contusions?

A
  • O2 provision
  • Will get worse over 48hours and then should stop
    progressing and resolve over 3-10 days
  • Rads lap about 12-24hrs
  • CT better
  • No abs needed
21
Q

What are causes of lung lobe torsion?

A
  • Sighthounds and pugs - idiopathic due to
    conformation
  • Neoplasia
  • Pleural space disease
  • Trauma

Left cranial lung lobe is the most common in pugs
Right middle and left cranial in sighthounds
Acute or chronic

22
Q

What are the 4 mechanisms of pleural effusion?

A
  1. Increased hydrostatic pressure - CHF, pericardial
    disease
  2. Increased vascular leakage - vasculitis (secondary
    to sepsis, trauma, IM disease, neoplasia,
    pancreatitis)
  3. Decreased lymphatic drainage:
    obstruction/neoplasia leading to increased
    venous pressure and increased permeability
  4. Decreased oncotic pressure: hypoproteinaemia
    (decreased albumin = decreased oncotic pressure
    = deceased water in vessels = increase in fluid
    accumulation)
23
Q

Investigating PE after ruling out cardiac disease?

A

CBC
Comp
Trigly/cholesterol
Clotting
4Dx snap
FELV/FIV
FIP PCR

24
Q

Common causes of pyothorax

A

Dogs: secondary to migrating FB or penetrating injury, haematogenous spread

Cats: Penetrating injury to chest from bite wounds, extension of pulmonary infections, haematogenous spread

25
Q

Dx and Medical Mx of Pyothorax

A

Dx - intracellular bacteria in plerural fluid, CT

Mx-
1. Bilateral chest drains

  1. Flush chest regularly - 20ml/kg in small aloquats
    (stop if losing more than 10ml into chest),
    warmed hartmanns and flush till clear. q4-6hrs
    and then decrease q6-12hrs, generally needed for
    5-7 days
  2. ABs - coamox + metro pending culture/sens

Remove drain when fluid production 2ml/kg/day per drain