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FRACP clinicals > Respiratory long > Flashcards

Respiratory long Flashcards

1
Q

How common is pulmonary fibrosis in sarcoidosis?

A

20% of patients with pulmonary sarcoidosis will develop pulmonary fibrosis as a result of inflammation

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2
Q

Treatment of pulmonary sarcoidosis

A

Asymptomatic - observation and monitoring w CXR/lung fumction 3-6 monthly
Symptomatic/progression - oral glucocorticoids
If cough is only symptom - inhaled glucocorticoid

Attempt to wean steroids after 4-6 weeks if improving

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3
Q

Examination findings of idiopathic pulmonary fibrosis

A

Clubbing (also present in abestosis)
Cyanosis
Lower lobe crackles - fine late inspiratory
Exclude CTD signs on exam

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4
Q

What antifibrotics have been approved for IPF

A

Pirfenidone

Nintedanib

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5
Q

AE of pirfenidone

A

GIT
Rash
LFT derangement

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6
Q

AE of nintedanib

A

VEGF inhibitor - inhibitsound healing

Not recommended in child pugh B/C

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FRACP clinicals (24 decks)

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