Respiratory: - Lecture 8. Respiratory Infection Flashcards
What are the clinical presentations of Influenza?
Fever: high, abrupt onset Malaise Myalgia Headache Cough Prostration
What are the two types of classical flu?
Influenza A Viruses
Influenza B Viruses
What is Haemophilius Influenzae?
- Bacterium
- Not a primary cause of ‘flu
- May be a secondary invader
How is flu transmitted?
Transmission is by droplets, or through direct contact with respiratory secretions of someone with the infection
What are flu complications?
Primary Influenzal Pneumonia
Secondary Bacterial Pneumonia
Bronchitis
Otitis Media
What antivirals can be perscribed for flu?
Oseltamivir
Zanamivir
What are the symptomatic treatments for Flu?
Bed Rest
Fluids
Paracetamol
What is the epidemiology of flu?
Seen in Winter epidemics
What is a minor mutation in flu called?
Antigenic drift
- This causes the winter epidemic
What is a Major mutation is flu called?
Antigenic drift
- This causes Pandemics
What is required for the flu to become a pandemic?
Antigenic shift
Segmented Genome
Animal Reservoir
How is Influenza detected?
PCR Immuofluorescence Antigen Detection Virus culture Antibody detection
How is Flu prevented?
Killed Vaccine
Live Attenuated Vaccine
What viruses cause Pneumonia?
Mycoplasma pneumoniae
Coxiella burnetii
Chlamydia
How is bacteria related pneumonia treated?
All respond to Tetracycline and Macrolides