Respiratory Infections Flashcards

1
Q

What things can compromise respiratory defences?

A
Poor swallow (stroke patients, muscle weakness)
Abnormal ciliary function, cystic fibrosis, brnchiectasis, HIV, immunosuppression
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2
Q

What are the upper respiratory tract infections?

A

Rhinitis, pharyngitis, epiglottitis, laryngitis, sinusitis, otitis media (commonly caused by viruses)

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3
Q

What is pneumonia?

A

Infection of lung parenchyma

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4
Q

What are the lower respiratory tract infections?

A

Bronchitis, bronchiolitis, pneumonia

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5
Q

What are the symptoms of acute bronchitis?

A

Cough, fever, increased sputum production, increased SoB

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6
Q

What organisms are most likely to cause acute bronchitis?

A

Viruses, Strep pneumoniae, Haemophilus influenzae

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7
Q

How does pneumonia present?

A

Fever, cough, pleuritic chest pain, shortness of breath

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8
Q

What are the typical organisms that cause community acquired pneumonia?

A

Strep pneumoniae, H influenzae

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9
Q

What are some atypical organisms that can cause community acquired pneumonia?

A

Legionella, mycoplasma, chlamydia psittaci

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10
Q

What could be found on examination of a patient with pneumonia?

A

Pyrexia, tachycardia, tachypnoea, cyanosis, dullness on percussion, bronchial breathing, crackles

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11
Q

What investigations would be carried out if pneumonia is suspected?

A

FBC, U&E, CRP, ABG, CXR

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12
Q

What samples can be taken for microbiological investigation of pneumonia?

A

Sputum, blood culture, nose and throat swabs, urine, serum

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13
Q

What scoring system is used when deciding how to manage pneumonia?

A

CURB65

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14
Q

How does CURB-65 work?

A
Confusion
Urea > 7 mmol/l
Respiratory rate >30
BP <90 systolic or <60 diastolic
>65 years old

Each score 1 point, if score is >2 manage as severe

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15
Q

Suggest an antibiotic for mild-moderate community acquired pneumonia

A

Amoxicillin or doxycycline

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16
Q

Suggest an antibiotic for severe community acquired pneumonia

A

Co-amoxiclav and clarithromycin

17
Q

What are some complications of acute bacterial pneumonia?/

A

Lung abscess, bronchiectasis, empyema

18
Q

What is the gram stain of strep pneumoniae?

A

Gram positive diplococci

19
Q

What is unique about atypical organisms that cause pneumonia?

A

No cell wall - penicillins don’t work

20
Q

Suggest an antibiotic to treat pneumonia caused by an atypical organism

A

Clarithromycin, doxycycline

21
Q

What is the aetiology of hospital acquired pneumonia?

A

Staph auerus, psudomonas spp, H influenzae, fungi, enterobacteriaciae

22
Q

What is the first line treatment for hospital acquired pneumonia?

A

Co amoxiclav

23
Q

What antibiotics are used for ITU patients with hospital-acquired pneumonia?

A

Tazocin, meropenem