Chemical Control of Breathing Flashcards

1
Q

What happens to pO2 and pCO2 in hyperventilation?

A

pO2 rises

pCO2 falls

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What happens to pO2 and pCO2 in hypoventilation?

A

pO2 falls

pCO2 rises

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What does hypercapnia do to plasma pH?

A

Leads to a fall in plasma pH

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What does hypocapnia do to plasma pH?

A

Leads to a rise in plasma pH

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Where are peripheral chemoreceptors located?

A

Carotid and aortic bodies

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What do large falls in pO2 stimulate?

A

1) Increased breathing
2) Changes in heart rate
3) Changes in blood flow distribution - eg increasing flow to brain and kidneys

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Where are central chemoreceptors located?

A

Medulla of the brain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Central chemoreceptors respond to changes in pH of what?

A

CSF

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is CSF [HCO3-] controlled by?

A

Choroid plexus cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Is the blood brain barrier permeable or impermeable to HCO3-?

A

Impermeable

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is the range for pCO2?

A

4.7-6.0 kPa

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is the range for pO2?

A

9.3-13.3 kPa

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What is the range for bicarbonate?

A

22-26mmol/L

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is type I respiratory failure?

A

Type 1 respiratory failure is defined as a low level of oxygen in the blood (hypoxemia) without an increased level of carbon dioxide in the blood (hypercapnia)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is type II respiratory failure?

A

Type 2 respiratory failure is caused by inadequate alveolar ventilation; both oxygen and carbon dioxide are affected.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly