Respiratory extra Flashcards

1
Q

What would be the cause of chronic dyspnoea, normal spirometry and lung volumes but a low TCLO?

A

P.E

Anaemia

Pulmonary artery hypertension

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2
Q

What are some causes for a low TCLO?

A

Intestinal lung disease

Emphysema

Cardiac failure

P.E

Anaemia

TCLO is determined by two factors:

  • alveolar surface volume
  • blood flow to the lung

Anything that affects these will lead to a reduction.

*note that asthma can be normal or lead to higher TCLO due to neovascularisation

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3
Q

if there is a complete flat top to a pleural effusion - what does that suggest?

A

Suggest there is air in the pleural space as well

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4
Q

What is the management of a pleural effusion?

A

Investigations:

  • Chest x-ray
  • US guided sample

Lights criteria
Immunology testing (autoimmune)
Cytology (malignancy)
Cultures and gram staining

Treatment:

  • treat underlying cause
  • Drainage if symptomatic - Drain no more than 1.5L and do not drain to empty

Pleurodesis with talc
or
Surgical fixation of pleura

Malignant management:

  • Medical pleurodesis
  • indwelling catheter
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5
Q

What is the management of pleural empyema?

A

Diagnostic when:
pH <7.2
LDH high
Low glucose

management:
- chest drain
- IV antibiotics
- DVT prophylaxis

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6
Q

When must a ABG be done over a VBG?

A

For accurate reading of paO2 and accurate readings of paCO2

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7
Q

What are the complications of obstructive sleep apnoea?

A
HTN 
Increased risk of stroke 
Type II respiratory failure 
Car accidents 
Cor pulmonale
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8
Q

What are the types of pneumothoraxes that occur?

A

Spontaneous

  • primary
  • secondary

Trauma

  • iatrogenic
  • traumatic
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9
Q

When can the canula used for the immediate management of a tension pneumothorax be removed? and when is the chest drain removed?

A

Once the chest drain is inserted and bubbling

Chest drain removed once it stops bubbling - demonstrating all the air has been removed from the pleural space.

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10
Q

List some potential findings seen in the blood work up and skin and CNS of atypical pneumonia:

A

FBC:
- haemolytic anaemia - mycoplasma

U&Es
- hyponatremia - legionella (SIADH)

Skin:
- erythema multiforma - mycoplasma

CNS:
- hyponatremia

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11
Q

What are the clinical features of sarcoidosis and how is investigated?

A

Skin:

  • erythema nodosa
  • lupus perinio

Eyes:

  • keratoconjunctivitis sicca
  • Anterior uveitis

Neurological:
- peripheral neuropathy

Cardio:

  • cor- pulmonale
  • conduction
Investigations: 
Bloods: 
- FBC (anamia) 
- U&Es (kidney involvement) 
- Ca2+ levels 

Orifices:
- Bronchoscopy with biopsy

x-rays:

  • CXR
  • CT scan
  • Echocardiogram

ECG
- for heart

Special test:
- ACE levels

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12
Q

What bloods do you want in a patient presenting with an acute exacerbation of COPD and what are some differentials and how are you going to manage them?

A
Investigations: 
- FBC
- U&Es 
- CRP 
- ABG 
\+/- Theophylline levels 
  • Sputum cultures
  • CXR

Differentials:

  • pneumonia
  • pneumothorax
  • P.E
  • Left ventricular failure

Management:

  • Oxygen - venturi mask 28% until ABG back
  • Steroids
  • Nebs - salbutamol/ ipratropium
  • Antibiotics
  • Chest physio
  • DVT prophylaxis
    +/- carbocysteine
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13
Q

List some causes, features and investigations into hypersensitivity pneumonitis:

A

Causes:

  • Farmer’s lung - Micropolyspora faeni
  • Maltworker’s lung - aspergillus
  • Pigeon fanciers lung
  • Chemical worker’s lung

Investigations:

  • CXR (fluffy nodular shadowing)
  • Anti-bodies towards to allergen
  • High resolution CT scan (Ground class and honeycombing)
  • Spirometry
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14
Q

What are the main types of work related lung injuries and what is the no.1 presenting symptom of mesothelioma?

A

Coal workers Pneumoconiosis

Silicosis

Asbestosis

Mesothelioma

*mesothelioma presents with unilateral painful pleural effusion

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15
Q

List some risk factors for IPF:

A
Smoking 
Chronic aspirations 
EBV 
Coeliac disease 
IBD
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16
Q

What are the clinical features of IPF and how is diagnosed and list some features that would be seen if a biopsy was done:

A

Features:

  • progressive dyspnoea
  • weight loss
  • Non-productive cough
  • clubbing
  • velcro-like crackles on inspiration

Investigations:

  • FBC (neutrophils/ eosinophils?)
  • Autoimmune serology? - RA? SLE?
  • ABG

X-rays:

  • High resolution CT (ground class and honey combing)
  • Echocardiogram (cor-pulmonale)

ECG:
- cor- pulmonale

Special tests:
- spirometery

Biopsy:

  • temporal heterogenicity
  • fibroblastic foci
17
Q

What are the functional levels of COPD?

A

all have FEV1/FVC <0.7

FEV1:

  1. > 80%
  2. 50-80%
  3. 30-50%
  4. <30%
18
Q

Following an acerbation of COPD what things need to be liased with the GP?

A

Smoking cessation

Vaccinations

Assessment for oxygen therapy?

19
Q

List some key investgiatiosn warrented in a P.E:

A

FBC - polycaethemia, underlying infection?
Coagulation studies
ABG

ECG

CXR - patients still get a CXR
CTPA

20
Q

What advice can be given to prevent a P.E on a flight?

A

Hydration
75mg aspirin if appropriate
Move when possible
Avoid alcohol

21
Q

What blood tests do you want into lung cancer?

A

FBC - anaemia?
LFTs - metastasis?
Bone profile - Mets, Ca2+
U&Es - paraneoplastic

22
Q

What conditions are associated with IPF?

A

RA
SLE
IBD