Palliative medicine Flashcards
What is meant by titration in pain medicine?
When a patient uses more frequent “as required” doses on top of their daily dose, the following day the “as required” is added onto their daily dose.
this keeps occurring until the symptoms settle and a balance is met
What are some signs of opioid toxicity?
Confusion Drowsiness myoclonus nightmares hallucination
What drugs can be used for N&V in patients?
Start with things such as metoclopramide *avoid in bowel obstruction due to the promotility effects
Ondansetron - 5HT3 antagonist can be used for severe
What is the conversion from oral codeine to oral morphine?
divide by 10
What is the conversion from oral morphine to subcut morphine?
Divide by 2
What is a useful mechanism to aid shortness of breath in a terminally ill patient?
Hand fan over the patient
- due to temperature change of air stimulates reflexes to slow breathing
What is an effective tool that can be used to aid the treatment received in hospice into a hospital setting?
Liverpool care pathway
- 4 step approach
What are some common symptoms of palliative care?
Dry mouth
Excessive Respirations
Restlessness
Nausea and vomiting
What drugs can be used for excessive respiratory secretions?
Hyoscine butylbromide
Glycopyrronium bromide
What drugs are used for nausea in palliative medicine??
Metoclopramide
Haloperidol
What drugs can be used for intractable hiccups?
Chlorpromazine
or
Haloperidol
What medication can be used for bowel obstruction pain?
Hyoscine Butylbromide
What can be used for respiratory secretions?
Hyoscine hydrobromide
**remember secretions with “hydro”
What dose should be given when changing from oral morphine to SC diamorphine?
divide by 3
Which drugs are ideal to use in severe kidney disease for pain relief?
Fentanyl
Alfentanil
Buprenorphine
If you are switching someone from oral codeine to oral morphine, what dose should you give?
Divide by 10
What does metastatic bone pain respond too?
Analgesia
Bisphosphonates
Radiotherapy
Confusion in a palliative patient, what is the management?
Look for reversible causes:
- hypercalcaemia
- infection
- urinary retention
1st line: Haloperidol
2nd line: Chlorpromazine