Emergencies Flashcards
What is the definition of a major haemorrhage?
50% blood loss within 3 hours
> 150mls per minute
Full circulatory volume lost in 24 hours
What should the management be during a major haemorrhage?
- Assess if this is a major haemorrhage
- put out major haemorrhage protocol - Restore circulating volume
- IV access
- Fluids - warm if possible - Stop bleeding
- Send samples
- emergency cross match
- FBC
- Clotting studies
- ROTEM
- U&;Es
- ABGs - Give blood products
What is made available following a major haemorrhage protocol?
6 units of RBCs
- O negative will be provided until a 2nd cross matched sample is received
If there is trauma, obstetric or risk of DIC what should also be requested upon the major haemorrhage protocol?
FFP
Platelets may also need to be requested
How long does a group specific, cross match take?
- where can O neg blood be found?
Group and save: 25 mins
Cross match: 60 mins
O Neg can be found in:
- Blood bank
- Satellite fridges
What haemoglobin should be aimed for in Major haemorrhage?
Hb> 80g/L
How much time for products do you need to leave during a major haemorrhage?
20mins thawing time for FFP
25 mins for group specific RBCs
60 mins for crossmatch
Transport time
What drug can be given during a major haemorrhage to help control bleeding?
Tranexamic acid
IV infusion - slowly initially.
then transfusion over 24 hours
What is the ideal blood product use for DIC?
Cryoprecipitate - contains fibrinogen
What are the different types of shock?
Cardiogenic shock Hypovolemic shock Septic shock Neurogenic shock Anaphylactic Obstructive
What are the classifications of shock?
Type I: <750ml 15% <100bpm BP normal slight anxious
Type II: 750-1500ml 15-30% 100-120bpm BP normal Mildly anxious
Type III: 1500-2000 30-40% 120-140 BP lowered Anxious confused
Type IV: >2000 >140 BP lowered RR>35 Confused lethargic
How do you manage a haemorrhage causing shock?
- Assess if this is a major haemorrhage
- put out major haemorrhage protocol - Restore circulating volume
- IV access
- Fluids - warm if possible - Stop bleeding
- active haemorrhage control
- direct compression
- pelvic binder - Send samples
- emergency cross match**
- FBC
- Clotting studies
- ROTEM (assesses haemostasis in patients)
- U&Es
- ABGs - Give blood products
- give O neg blood initially then move to group specific when able
How much and how quickly should a fluid bolus be given in an emergency situation?
500ml saline over 15 mins
or
250ml in heart failure over 15mins
List some causes of cardiogenic shock:
M.I
Mitral regurgitation
Subarachnoid inducing catecholamine release causing cardiogenic stunning
Name some causes of obstructive shock
P.E
Cardiac tamponade
Tension Pneumothorax
List some causes of neurogenic shock, and explain the underlying pathological mechanisms:
High cervical cord trauma
Major brainstem or spinal injury
Guillain Barre syndrome
Loss of vasomotor control induces mass peripheral dilation.
Also damage to sympathetic nerves system can induce severe bradycardia
What are some clinical features of septic shock?
Warm peripheries
Bounding pulse
Large pulse pressure (120/ 50)
What are some clinical features of Anaphylactic shock?
Wheeze Stridor Angioedema - especially facial and laryngeal Itch Urticaria Bounding pulse warm peripheries Large pulse pressure
What are some mimics of anaphylaxis?
Carcinoid syndrome
Pheochromocytoma
Angioedema
Mastocytosis
What should be measured to confirm anaphylactic reaction and when?
Tryptase
1 - 6 hours following onset
What is the management of hemorrhagic shock following from initial ABC (i.e. fluids and oxygen is already on)?
Stop bleeding
- pelvic binders
- Leg splints
Contact Haematology
Give blood and FFP (1:1 ratio)
- O Neg
- specific blood
Platelets (keep >100) - platelets
Fibrinogen (>1) - cryoprecipitate
Tranexamic acid
Following ABCDE if someone is in cardiogenic shock, how are you going to treat them?
Diamorphine
- reduce pain and anxiety
Correct arrhythmias and U&E abnormalities
Optimise filling pressures:
Underfilled:
- Plasma expanders
Underfilled:
- Inotropic support - dobutamine
- Nitrates
Name some complications of shock:
Hypoperfusion to vital organs which may cause irreversible damage.
- Brain - coma
- Kidneys
- Ischemic Hepatitis
- Myocardial ischemia
What clinical signs may you see with cardiogenic shock?
Low BP/ High diastolic Weak pulse Raised JVP Low GCS Oliguria Cool peripheries
What is the management of anaphylaxis ?
Secure Airway
- intubation may be needed
Remove cause
IM adrenaline - 0.5mg - 1:1000ml - repeat every 5 mins if needed \+ IV chlorpheniramine \+ IV steroids
IV saline
still hypotensive: - ICU - IV Adrenaline \+ - IV aminophylline
What are the generalised stages of shock?
Initial
Compensating
Progressive/ Decompensating
Refractory/ irreversible
List some signs of hypovolemic shock?
altered mental status
Cool clammy skin
Mottled skin
weak, thready pulse
tachycardia
thirsty/ dry/ low JVP
Pupil dilation
In E of the ABCDE, what are you looking for in shock?
Signs of blood loss:
- injury sites
- penetrations
- bruising across the flanks / abdomen
- High riding prostate
Signs of infection:
- Rash
When should someone be admitted following a head injury?
<15 GCS Focal neurological symptoms Vomiting Amnesia Alcohol ingestion Coagulopathy Suspected cranial fracture
What are the signs of a basal skull fracture?
Panda eyes Hemotympanum Otorrhoea - CSF from ears Rhinorrhoea - CSF from nose Battle's sign - bruising on mastoid
What is a LBBB in keeping with in the setting of an M.I?
Large anterior M.I
What are the rhythms that cause arrest?
PULSELESS VT
VF
Pulseless electrical activity
Asystole
How are you going to monitor a patient with shock?
Mental status Vitals - HR, BP, RR, Stats Cap Refill Urine output ECG Skin colour and temperature CVP - if in place
What immediate investigations do you want when someone is in shock?
Bloods: - FBC - U&Es - ABG - Coagulation studies - LFTs - Glucose \+/- CRP \+/- Blood cultures
Orifices:
- Urine output
+/-
urinalysis
X-rays:
- Ultrasound of heart (if cardiosuspected)
+/-
CXR
ECG
Special tests:
- tryptase
- D-dimer
How are you going to monitor someone following shock?
Mental status Urine output Vitals - HR, STATS, BP Skin Colour Cap Refill CVP ECG
What makes up the trauma triad?
Hypothermia
Coagulopathy
Acidosis
If you are at bedside with a patient who has collapsed, what bedside investigation should you always do?
BM’s
In addition to atropine, what additionally inputs can be done into severe bradycardia?
external pacing
Adrenaline
Temporary pacing wire
What important medication must be given when there is stridor and oxygen sats falling?
Nebulised Epinephrine
+
Contact anesthetists
List actions you would take during a AAA?
Major haemorrhage protocol
Give O negative blood
Senior help/ Vascular surgery
What bedside tests can be done to confirm an AAA?
Ultrasound
FAST scan
**CT confirms whether it has rupture
Give some differentials for stridor:
Inspiratory:
- Epiglottitis
- Glandular fever
- Laryngitis
- Croup
Expiratory:
- Tracheal compression
If a person goes into cardiac arrest following a P.E and is treated with thrombolysis - how long should CRP be continued for?
90 minutes.
thrombolytic drug needs time to work
If someone presents with a collapse - what is a very important aspect of the systemic enquiry history you want to ask about?
Melena or G.I bleed.
they be volume depleted leading to low BP
What signs may you see during a P.E?
Tachypnea
Pleuritic chest pain
Hemoptysis
Syncope
Right ventricular heave
Loud 2nd heart sound
Splitting of heart sound
Increased JVP
Management of a P.E?
Oxygen Fluids LMWH or Thrombolysis
Immediate management of NSTEMI:
Beta blockers Aspirin Ticagrelor Morphine Anticoagulation - LMWH Nitrates \+/- Oxygen (<94%)
GRACE Score
>10% = PCI or CABG
Follow up they will need:
- Echocardiogram
- Stress ECG
- Angiogram
During an upper G.I bleed, when should O- blood be given?
If they patient is severely unstable or Hb <7
When in an upper G.I bleed is terlipressin and antibiotics given?
If high suspicion of varices i.e. liver failure.
given before scope
What are the initial symptoms of anaphylaxis?
Tingling
Warmth
Itchiness
Mild oedema
followed by:
- urticaria
- generalised flush
- wheeze
- bronchospasm
- hypotension
What biochemical directly correlates with the severity of an anaphylactic reaction?
Serum Platelet Activating Factor