Respiratory Drugs Flashcards

1
Q

Three types of decongestants

A

Pseudoephedrine, oxymetazoline, phenylephrine

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2
Q

Four types of antitussives

A

Dextromethorphan, benzonatate, codeine, hydrocodone bitartrate

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3
Q

Action of antitussives

A

They act on the cough centers of the medulla, throat, trachea, and lungs to raise the threshold for coughing

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4
Q

Action of decongestants

A

They act on adrenergic receptors to trigger vasoconstriction and indirectly cause the release of norepinephrine

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5
Q

Which drug should be avoided when taking decongestants?

A

Any MAOI

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6
Q

What substances should be avoided when taking antitussives?

A

St. John’s Wort, ETOH, sedative-hypnotic drugs, and antidepressants

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7
Q

Why should ET0H, sedative-hypnotics, and antidepressants be avoided when taking antitussives?

A

They increase the risk of CNS depression

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8
Q

What type of drug is guaifenesin?

A

Expectorant

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9
Q

Action of expectorants

A

They liquify the respiratory secretions and loosen mucus to make it easier to cough it up

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10
Q

BUN and Cr should be monitored in renal patients and children when administering which drug?

A

Guaifenisin/expectorants

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11
Q

Diphenhydramine (Benadryl) is what generation of antihistamine?

A

First

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12
Q

Cetirizine (Zyrtec) and Loratadine (Claritin) are what generation of antihistamine?

A

Second

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13
Q

Fexofenadine (Allegra) is what generation of antihistamine?

A

Third

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14
Q

This antihistamine can cause thrombocytopenia, agranulocytosis, and hemolytic anemia

A

Diphenhydramine (Benadryl)

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15
Q

Top three bronchodilators

A

Beta-2 adrenergic receptor antagonists, anticholinergics, xanthines

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16
Q

What is the top risk when using theophylline and why?

A

Drug toxicity due to its narrow therapeutic index

17
Q

True or false: leukotrine receptor antagonists are used for acute asthma attacks

A

False

18
Q

Which asthma medication has a BBW due to it having potentially neuropsychotic adverse effects?

A

Montelukast

19
Q

Which two TB drugs can cause eye problems?

A

INH and ethambutol

20
Q

What is the most serious side effect of pyrazinamide (PZA) and why?

A

Gout, because it inhibits uric acid secretion

21
Q

What is the most serious side effect of isoniazid (INH) and why?

A

Neuropathy, because it inhibits absorption of Vitamin B6