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CPT Drugs > Respiratory Drugs > Flashcards

Respiratory Drugs Flashcards

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NASM ® CPT flashcards
1
Q

Inhaled corticosteriod examples

A

Beclometasone

Budesonide

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2
Q

Inhaled corticosteriod indications

A

Asthma when reliever is not sufficient

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3
Q

Inhaled corticosteriod mechanism of action

A

Reduces mucosal inflammation
Widens airways
Reduced mucus production
Reduces exacerbations

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4
Q

Inhaled corticosteriod ADR

A

Candidiasis

Horse voice

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5
Q

Inhaled corticosteriod cautions

A

Pneumonia risk possible in COPD at high doses

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6
Q

Inhaled corticosteriod DDI

A

Very few if taken correctly

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7
Q

SABA example

A

Salbutamol

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8
Q

Fast acting LABA example

A

Formoterol

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9
Q

Slow acting LABA example

A

Salmeterol

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10
Q

When to use SABA inhaler ?

A

Symptom relief through reversal of bronchoconstriction when required

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11
Q

Beta agonist mechanism of action

A

Bind to beta 2 receptors and cause activation of adenylyl cyclase increasing production of cAMP. This increases activity of PKA and causes bronchial smooth muscle relaxation.
It also increases mucus clearance by action of cilia

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12
Q

Beta agonist ADR

A 
Tachycardia 
Sweating
Palpitations 
Anxiety 
Tremor
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13
Q

Beta agonist cautions

A

LABA should only be prescribed alongside inhaled corticosteriods

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14
Q

Beta agonist DDI

A

Beta blockers reduce effects on beta agonists

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15
Q

Montelukast drug class

A

Leukotriene receptor antagonist

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16
Q

Montelukast mechanism of action

A

Blocks leukotrienes from binding to receptors decreasing bronchoconstriction, mucus production and oedema

17
Q

Montelukast ADR

A

Headache
GI disturbance
Dry mouth

18
Q

Montelukast DDI

A

No major drug interactions reported

19
Q

Tiotropium drug class

A

LAMA

20
Q

Tiotropium indication

A

Severe asthma

COPD

21
Q

Tiotropium mechanism of action

A

Blocks vagally mediated contraction of airway smooth muscle

22
Q

Tiotropium ADR

A

Anticholinergic effects - dry mouth, urinary retention, dry eyes

23
Q

Theophylline drug class

A

Adenosine receptor antagonist

24
Q

Theophylline indications

A

Poorly controlled asthma

25
Q

Theophylline mechanism of action

A

Blocks adenosine receptors causing decreased bronchoconstriction

26
Q

Theophylline cautions

A

Potentially fatal complications

Narrow therapeutic index

27
Q

Theophylline DDI

A

CYP450 inhibitors increase conc

28
Q

Ipratropium drug class

A

SAMA

29
Q

Ipratropium indication

A

Used alongside beta agonists if poor response alone

CPT Drugs (9 decks)

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