Respiratory Conditions Flashcards

1
Q

Who is most likely to be affected by acute asthma?

A

CHILDREN-

boys and WOMEN

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2
Q

What is the cause of acute asthma?

A

It is the PAROXYSMAL and REVERSIBLE obstruction of the airways.
INFLAMMATORY condition combined with bronchial hyper-responsiveness
BRONCHOSPASM: smooth muscle spasm -narrowing of airways
EXCESSIVE SECRETIONS - pluggin airways

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3
Q

What are the risk factors associated with asthma?

A

NON-MODIFIABLE: family history of asthma/atopy, maternal smoking, prematurity and low birth weight
MODIFIABLE: smoking, obesity
PMH: personal history of atopy

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4
Q

What are the most noticeable symptoms related to asthma?

A
Wheeze
Breathlessness
Chest tightness
Cough
Worse at night and early in the morning
Worse in response to exercise/allergen exposure/cold air
Worse after aspirin/beta blocker use
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5
Q

What are the clinical signs of acute asthma?

A

Wheeze
Low FEV1
Low peak flow

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6
Q

What are some differential diagnoses for acute asthma?

A
Bronchiolitis
Cystic fibrosis
GORD
Croup
Bronchiectasis/tuberculosis
COPD
Heart failure/CHD
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7
Q

Which investigations are appropriate in acute asthma?

A

Peak flow
Spirometry
CXR

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8
Q

What is the management for acute asthma?

A

Beta agonist for relief (salbutamol)

Regular inhaled steroid (beclometasone diproprionate)

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9
Q

Who is most typically affected by bronchial carcinoma?

A

WOMEN

increasing age

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10
Q

What is the most likely cause of bronchial carcinoma?

A

Non-small cell lung cancers
SMOKING
ASBESTOS

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11
Q

What are the risk factors for developing bronchial carcinoma?

A

NON-MODIFIABLE: increased age
MODIFIABLE: smoking, asbestos, chromium, arsenic, iron oxide, radiation
PMH: COPD, previous cancer

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12
Q

What are the symptoms of bronchial cancer?

A
WEIGHT LOSS
HAEMOPTYSIS
BONE PAIN
COUGH
DYSPNOEA
clubbing, fever, weakness, SVC obstruction, dysphagia, headache, nausea/vomiting, hoarseness, wheezing/stridor
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13
Q

What are the clinical signs of bronchial carcinoma?

A

Opacity in CXR

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14
Q

What are some differentials for bronchial carcinoma?

A
Secondary malignancy
Arteriovenous malformation
Pulmonary haematoma
Bronchial adenoma
Abscesses
Granuloma
Encysted effusion
Cyst
Foreign body
Skin tumour
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15
Q

What investigations should be done in suspected bronchial carcinoma?

A

IMAGING: CXR, CT, PET, bronchoscopy
SAMPLING: biopsy

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16
Q

What is the treatment for bronchial carcinoma?

A

Surgery
Radiotherapy
Chemotherapy

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17
Q

Who is affected by COPD?

A

It is found in 3 million people in the UK and is more common in MEN

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18
Q

What is the primary cause of COPD?

A

SMOKING

other causes include: long term exposure to lung irritants, inherited alpha 1 antitrypsin deficiency

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19
Q

What are the risk factors for COPD?

A

NON-MODIFIABLE: genetic

MODIFIABLE: smoking, occupational exposure- asbestos, chromium, arsenic, iron oxide, radiation, air pollution

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20
Q

What are the main symptoms for COPD?

A

Exertional breathlessness, chronic cough, wheezing, regular sputum production, recurrent chest infections, weight loss, exercise intolerance, ankle swelling, fatigue

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21
Q

What are the clinical signs of COPD?

A
Use of accessory muscles in breathing?
Pursed lip breathing
Drowsiness/ flapping tremour, mental confusion
Cyanosis
Hyperinflation of the chest
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22
Q

What are the differential diagnoses for COPD?

A
Asthma
Congestive heart failure
Bronchiectasis
Allergic fibrosing alveolitis
Pneumoconiosis
Asbestosis
Tuberculosis
Lung cancer
Obliterative bronchiolitis
Bronchopulmonary dysplasia
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23
Q

What investigations should be done in suspected COPD?

A

Spirometry
CXR
BLOODS: FBC

24
Q

What is the best management for COPD?

A

Smoking cessation
INHALED THERAPY: short acting beta agonist (salbutamol), Short acting muscarinic antagonist (ipratropium)/ long acting beta agonist and muscarinic antagonist (salmeterol, tiotropium)
ORAL THERAPY: corticosteroids, theophylline, mucolytics (carbocisteine)
OXYGEN THERAPY
PHYSIOTHERAPY
PULMONARY REHAB

25
Who is most likely to be affected by lobar pneumonia?
the VERY YOUNG | ELDERLY
26
What are the causes of pneumonia?
BACTERIAL: s. pneumoniae, h.influenzae, chlamydophila pneumonia, mycoplasma pneumonia. VIRAL: rhinovirus, influenza virus, RSV, adenovirus, parainfluenza FUNGAL PARASITIC NON-INFECTIOUS
27
What are the risk factors for lobar pneumonia?
MODIFIABLE: smoking PMH: preceding viral infections, immunosuppression (AIDS, cytotoxic therapy), respiratory problems, IVDU, hospitalisation, aspiration pneumonia, underlying disease
28
What are the symptoms of lobar pneumonia?
``` Cough Purulent Sputum Breathlessness Fever Malaise ```
29
What are the clinical signs associated with lobar pneumonia?
``` Tachypnoea Bronchial breathing crepitations pleural rub dullness with percussion ```
30
What are some differential diagnoses for lobar pneumonia?
``` Acute bronchitis Congestive heart failure COPD exacerbation Asthma exacerbation Bronchiectasis exacerbation TB Lung cancer/METs Empyema ```
31
What are the investigations for lobar pneumonia?
``` CURB-65 Confusion Urea Respiratory rate BP 65 CXR ```
32
What is the treatment for lobar pneumonia?
Oxygen for treating hypoxia Fluids for dehydration Analgesics for mild pleuritic pain Nebulised saline Antibiotics- 5 DAY AMOXICILLIN (macrolide/tetracycline for pen. allergies and FLUCLOXACILLIN if staph infection is suspected) 7-10 days AMOXICILLIN and macrolide for moderate to severe Beta-lactamase and a macrolide for most severe (carbapenem)
33
Who is more likely to have pneumothoraces?
Men under 20 and peak at 60 | Women 30-34 and peak at 60
34
What are the causes of pneumothorax?
``` Primary- SPONTANEOUS Secondary- underlying lung disease TRAUMA IATROGENIC CATAMENIAL PNEUMOTHORAX ```
35
What are the risk factors of pneumothorax?
NON-MODIFIABLE: Marfan's MODIFIABLE: smoking PMH: endometriosis, subpleural blebs and bullae
36
What are the symptoms of pneumothorax?
Sudden onset of pain SOB Breathlessness
37
What are the clinical signs of pneumothorax?
``` Tachycardia Pulse paradoxicus asymmetry of chest wall during inspiration hyper resonance in percussion deviated trachea reduced/absent breath sounds ```
38
What are the differentials for pneumothorax?
Pleural effusion Chest pain Pulmonary embolism
39
What investigations are available for pneumothorax?
IMAGING: CXR, USS, CT SCAN BLOODS: ABG
40
What is the treatment for pneumothorax?
Needle aspiration- large bore needle Chest drain Oxygen Surgery
41
How common is pulmonary embolus?
It is the most common cause of post-operative death affecting 60-70 per 100,000
42
What are the causes of pulmonary embolus?
``` Thrombosis from DVT Tumours (breast and prostate) Fat Amniotic fluid Sepsis Foreign bodies Air ```
43
What are the risk factors for PE?
``` Surgery Obstetrics Malignancy Lower limb problems Reduced mobility Previous VTE Minor risk factors- cardiovascular, oestrogens, misc. ```
44
What are the symptoms of PE?
Dyspnoea Pleuritic chest pain Cough and haemoptysis
45
What are the clinical signs for PE?
``` Tachycardia, tachypnoea Hypoxia Pyrexia Elevated JVP Gallop heart rhythm Pleural rub Systemic hypotension and cardiogenic shock ```
46
What are the differentials for PE?
``` ACS Aortic dissection Cardiac tamponade Pneumonia Pneumothorax Sepsis ```
47
What investigations are required for PE?
BLOODS: d-dimers, ABG, FBC, troponin, BNP o2 sats IMAGINGL CXR, ECG, ECHO
48
What is the management for PE?
100% O2 Fluid restoration Anticoagulation- low weight molecular heparin, rivaroxaban Vitamin K antagonist
49
What is the cause of unilateral pleural effusion?
``` Results from accumulation of abnormal volumes of fluid in the pleural space. It can split into transudate and exudative Associated with- Cardiac failure Pneumonia Malignancy PE ```
50
What are the risk factors for unilateral pleural effusion?
MODIFIABLE: smoking, asbestos exposure PMH: Pre-existing lung damage/disease, lung cancer, liver cirrhosis, heart failure
51
What are the symptoms associated with unilateral pleural effusion?
``` Dyspnoea Breathlessness Pleuritic chest pain cough and haemoptysis weight loss ```
52
What are the clinical signs of unilateral pleural effusion?
finger clubbing rheumatoid changes in the hands accessory muscle use reduced movement on the side of the effusion tracheal deviation away from the lesioned side stony dullness on percussion diminished breath sounds over effusion
53
What are the differentials for unilateral pleural effusion?
``` Pulmonary oedema diaphragmatic injuries hypothyroidism pancreatitis rheumatoid arthritis ```
54
What investigations are appropriate in suspected unilateral pleural effusion?
IMAGING: CXR-PA SAMPLING: pleural aspiration (thoracentesis), centrifuge, haematocrit, cholesterol and triglycerides BLOODS: ESR, CRP, albumin, amylase, TFTs, blood culture
55
What is the treatment for unilateral pleural effusion?
Pleural drainage Tapping the fluid Pleurodesis- injection of sclerosant to cause adhesion of visceral and parietal pleura and prevents re-accumulation. (tetracycline, sterile talc, bleomycin)