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Microbio II Exam 2 > Respiratory > Flashcards

Respiratory Flashcards

1
Q

basidiomycosis

cause

A

shrooms- coprinus and schizophylum

inhalation

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2
Q

basidiomycosis

ss

A

chronic lung lesions
meningitis
endocarditis following allergic reactions
(found in people that work OUTSIDE)

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3
Q

cheese washer

cause and ss

A

penicilum

skin rashes and resp problems

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4
Q

farmers lung cause and path

A

aspergillus or pénicillium
increased levels of igG* due to inhalation of hay with these spores

creates (type 3 allergic rxn)

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5
Q

farmers lung ss

A

acute symptoms of airway obstruction

shallow breathing, cough fibrotic deposits infiltrates and granulomas

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6
Q

lycoperdonosis cause and ss

A

lycoperdon or calvatia

cough and pneumonia

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7
Q

malt workers

A

allergic rxn to moldy barley containing aspergillus

cough and pneumonia

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8
Q

maple bark

A

bark of maple trees containing cryptostroma cortical

chronic cough

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9
Q

mushroom growrs

A

pleurotus

cough and labored breathing

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10
Q

pneumocystosis

A

pneumocystis jiroveci

opportunistic yeast

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11
Q

pneumocystosis
epi

target*

A

wordwide
human flora and rodents

affects IMMUNOCOMPROMISED People

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12
Q

pneumocystosis

path

A

multiply in lung tissue
form membrane around granulomas with an exudate

oxygen exchange is reduced, consolidation of the lungs

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13
Q

pneumocystosis

immunity

A

protective for immunoCOMPETENT peeps!!

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14
Q

pneumocystosis

ss

A

cough chest pain congestion anorexia SOB weight loss in immunocompromised people
cotton wool spots in retina

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15
Q

pneumocystosis

dx

A

thick walled crescent shaped cysts with internal bodies

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16
Q

pneumocystosis

tx

A

Cotrimoxazole

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17
Q

Aspergillosis

cause

A

aspergillus species (1500 types)

opportunistic mold

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18
Q

Aspergillosis
epi

transmission

A

worldwide

implantation of fomites, inhalation, ingestion p2p contact

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19
Q

Aspergillosis

path

A

causes pyogenic suppuration and necrosis and release of fungal endotoxins
granulation of tissue makes edema accesses thrombosis and infarctions

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20
Q

Aspergillosis

ss

A

athsma bronchitis
fungus balls* necrotizing pneumonia
headache fever dyspnea edema hemoptysis and pleuritic chest pain

disseminated:
proptosis nasal swellings
growths on heat valves, lesions on skin brain liver and kidney etc

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21
Q

Aspergillosis

dx

A

conidial structures or acute angle branching* in stained sputum

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22
Q

Aspergillosis

tx

A

amphotericin B

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23
Q

Aspergillosis
target

virulence affected by

A

its common in people who are IMMUNOSUPPRESED who have neutropenia or are in antibiotics

has dsRNA myxoviruses that represses formation of toxins

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24
Q

Geotrichosis

cause

A

Geotrichum candidum

monomorphic mold

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25
Geotrichosis epi transmission
worldwide transmission via inhalation of arthrospores person to person
26
Geotrichosis | path
development of masses of necrotic foci
27
Geotrichosis | ss
diffuse lesions in lungs, bronchitis oral-> thrush GI***-> Colitis
28
Geotrichosis | dx
septate hyphae with arthorspores in exudates
29
Geotrichosis | tx
ketoconazole
30
Mucormycosis epi transmission
worldwide soil fruit grain transmission via implantation of spore contaminated fomites, inhalation of patients who are immunocompromised (like diabetics or transplants recipients)
31
Mucormycosis | path
invade blood vessels-> causing necrosis thrombosis and infarction cause loss of arterial blood supply -> forming microabcesses and lesions become rubbery
32
Mucormycosis | ss
fever dyspnea bronchitis pneumonia hemoptysis, bacterial proptosis, swelling of the brain cutaneous is often seen in burn patients CNS-> head trauma
33
Mucormycosis | dx
broad branching non peptide with right angle branching
34
Mucormycosis | tx
amphothericin B
35
Hyalohyphomycosis | cause
acremonium fusarium penicilium scopulariopsis (mono opp mold)
36
Hyalohyphomycosis epi transmission
saprophytes all over world | inhalation, ingestion or person to person contact
37
Hyalohyphomycosis | path
mold secrete toxins, invade tissue producing thrombosis and infarctions
38
Hyalohyphomycosis | ss
granulomas/ abcesses-> pulmonary, cerebral, cut, GI, ocular
39
Hyalohyphomycosis | dx*
Darkly pigmented conidia in Vitro lightly pigmented hyphae in Tissue large branching septate combination of findings for
40
Hyalohyphomycosis | tx
amphoterixin B | (resistance to itraconazole)`
41
Blastomycosis | cause
blastomyces derm | PATHOGENIC dimorphic fungus
42
Blastomycosis epi transmission
Central and Southeastern US Africa Asia implantation/ inhalation of spores found in other animals but not transmitted by animals
43
Blastomycosis | path
yeast multiply and form pyrogenic access lesions develop in granulomatous caseous areas that CALCIFY crab claw shadow*
44
Blastomycosis | ss
dry cough chills pleuritic pain pneumonia sore throat myalgia fever and wt loss osseous-> osteomyelitis or septic arthritis systemic-> multiple organ systems
45
Blastomycosis **** | dx
Large BROAD based budding yeast ce;;s
46
Blastomycosis | tx
ketoconazole
47
coccidioidomycosis | cause
coccidiodes immitis | pathogenic Dimorphic fungus
48
coccidioidomycosis epi transmission aka
Arid and semi arid regions of South West UT and central and South America (aka valley fever) transmission via inhalation of arthrospores (its found in animals but we can't get it from them)
49
coccidioidomycosis | path
suppurative neutrophils that have endospores become necrotic-> form granulomas form cavities and scar
50
coccidioidomycosis | immunity
YES
51
coccidioidomycosis | ss
asymptomatic or fever chills headache pleuritic pain cough | allergic-> toxic eruptions aka desert bumps dorm
52
coccidioidomycosis | dx
thin walled spherules with endospores
53
coccidioidomycosis tx ab titerS?
amphotericin B | increase of ab titers== tx is not working
54
Histoplasmosis | cause
histoplasmosis capsulatum and duboisii | pathogenic dimorphic fungi
55
Histoplasmosis epi transmission
Capsulatum: worldwide-> but lots in ohiomissisipi valley in US Duboissi: africa and asia found un bird and bat guano via inhalation of fungal spores
56
Histoplasmosis | path
granulomas form | lesions inside macros and monos-> disseminate the disease
57
Histoplasmosis | immunity
partial
58
Histoplasmosis | ss
summer fever-> chills headache chest pain severe-> fever cough sob wt loss malaise
59
Histoplasmosis | dx
cells containing extra or intra oval yeasts with bud scars and thin walls also thermally dimorphic
60
Histoplasmosis | tx
amphotericin C | increased titers -> drugs not working
61
paragonimiasis | cause
paragonumus | lung fluke-> Trematode
62
paragonimiasis | epi
Asia africa and america human crab and non human mammals
63
paragonimiasis | how do we get sick
live in our lungs - from ingested metarceria in infected raw or undercooked crabs
64
paragonimiasis | life cycle
live in lungs of humans where eggs are releases- coughed or swallowed the miracidia hatch and develop in cercaria in snails -> which then penetrate crayfish and develop into metarceria we eat the metarceria and they live in our peritoneum and duodenum and then go to our lungs and mature
65
paragonimiasis | path
lung lesions caused by adult flukes or toxic substances -> forming cysts around the parasite if the cysts rupture they can release their contents and calcify
66
paragonimiasis | immunity
none
67
paragonimiasis | ss
pleurisy sob dyspnea fever wheezing hemoptysis
68
paragonimiasis | dx
thick shelled eggs with shoulders* | in rusty sputum or fecal concentrations
69
paragonimiasis | tx
praziquantel

Microbio II Exam 2 (7 decks)

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